Evaluation of Cognitive Functions in Obstructive Sleep Apnea Syndrome

Year 2020, Volume: 22 Issue: 1, 29 - 35, 30.04.2020

Mehmet Hamamcı Yavuz Selim İntepe Bülent Çiftçi

https://doi.org/10.18678/dtfd.674962

Cited By: 1

Abstract

Aim: The aim of this study is to evaluate patients with Obstructive Sleep Apnea Syndrome (OSAS) in terms of various cognitive functions and determine the relationship between cognitive functions with anxiety and depression levels.
Material and Methods: This cross-sectional study was conducted between June 15, 2019 and December 15, 2019 and included 34 OSAS patients and 28 healthy volunteers between the ages of 18-65 with at least primary education. All participants underwent overnight recording of polysomnography. Patients were evaluated using sociodemographic data form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Montreal Cognitive Assessment (MoCA) and the Stroop Color and Word Test (SCWT).
Results: There was no significant difference between the OSAS and control group in terms of age and gender. OSAS patients had significantly higher depression and anxiety scores compared to the control group. OSAS patients showed poor performance in naming, attention, abstract thinking, and delayed recalling compared to the control group. OSAS patients completed Stroop tests 1, 3, and 5 in a longer amount of time than the control group. Cognitive functions were found to have a significant negative correlation with apnea hypopnea index, BDI, and BAI scores.
Conclusion: OSAS was found to have a different effect on each subcomponents of cognitive function. Furthermore, it was determined that many negative factors caused by OSAS may play a role in cognitive involvement in OSAS. Further studies are warranted to shed light on the ethiopathogenesis of this subject.

Keywords

Stroop, attention, memory, abstract thinking, neurocognitive function

Thanks

We express our sincere appreciation to the patients with obstructive sleep apnea syndrome and the healthy volunteers who participated in this study.

Obstrüktif Uyku Apne Sendromunda Bilişsel Fonksiyonların Değerlendirilmesi

Abstract

Amaç: Bu çalışmanın amacı Obstrüktif Uyku Apne Sendromu (OUAS) hastalarını birçok bilişsel fonksiyon açısından değerlendirmek ve OUAS hastalarının bilişsel fonksiyonları ile anksiyete ve depresyon düzeyleri arasındaki ilişkiyi ortaya koymaktır.
Gereç ve Yöntemler: Bu kesitsel çalışmaya 15 Haziran 2019 ve 15 Aralık 2019 tarihleri arasında yapıldı ve 18-65 yaş arası en az ilkokul mezunu 34 OUAS hastası ve 28 sağlıklı gönüllü dahil edildi. Tüm katılımcıların bir gece boyunca polisomnografi kayıtları alındı. Tüm katılımcılara sosyodemografik veri formu, Beck Depresyon Ölçeği (BDÖ), Beck Anksiyete Ölçeği (BAÖ), Montreal Bilişsel Değerlendirme (MoCA) ve Stroop Renk ve Sözcük Testi (SCWT) uygulandı.
Bulgular: OUAS ile kontrol grubu arasında yaş, cinsiyet açısından anlamlı fark yoktu. OUAS hastalarının depresyon ve anksiyete ölçek puanları kontrol grubuna göre anlamlı şekilde daha yüksekti. OUAS hastalarının adlandırma, dikkat, soyut düşünme ve gecikmeli hatırlama performansları kontrol grubuna göre daha düşük idi. OUAS hastaları Stroop 1, 3 ve 5 testini kontrol grubundan daha uzun bir sürede tamamladı. Bilişsel fonksiyonların apne hipopne indeksi, BDÖ ve BAÖ skorları ile negatif yönde anlamlı bir korelasyonu olduğu bulundu.
Sonuç: OUAS’ın bilişsel fonskiyonların her bir alt birleşeni üzerinde farklı bir etkisinin olduğu saptandı. Ayrıca OUAS’daki bilişsel etkilenmenin altında, OUAS’ın neden olduğu birçok olumsuz faktörün rolü olabileceği tespit edildi. Bu konunun etyopatogenizin daha açık hale gelmesi için ileri çalışmalara ihtiyaç vardır.

Keywords

Stroop, dikkat, hafıza, soyut düşünme, nörokognitif fonksiyon

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