Year 2020, Volume 22 , Issue 1, Pages 67 - 70 2020-04-30

Otoimmun Komplikasyonlarla Seyreden Yaygın Değişken İmmün Yetmezlik Hastasında Renal Amiloidoz
Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications

Gökhan AYTEKİN [1] , Fatih ÇÖLKESEN [2] , Eray YILDIZ [3] , Hacı ESEN [4] , Şevket ARSLAN [5]


Yaygın değişken immün yetmezlik (YDIY), bozulmuş antikor üretimi ve yetersiz B hücresi farklılaşması ile karakterize nadir görülen bir birincil immün yetmezlik tablosudur. Her ne kadar YDIY hastalarında sık tekrarlayan solunum yolu enfeksiyonları en belirgin klinik durum olsa da; YDIY, lenfoid hiperplazi, otoimmün sitopeni, kronik akciğer hastalıkları, granülomatöz hastalıklar ve maligniteye yatkınlık gibi birçok sistem ve organı etkileyen heterojen bir immün sistem bozukluğudur. Bu durum, tanı ve immünoglobulin replasman tedavisinde gecikmeye, uygun dozda ve zamanda antibiyotik alınamamasına, kronik inflamasyona ve dolayısıyla sekonder amiloidoza yol açabilir. Bu vaka sunumunda, otoimmün komplikasyonla seyreden bir YDIY olgusu ve takip sırasında gelişen renal amiloidoz tablosunun sunulması amaçlanmıştır.

Common variable immune deficiency (CVID) is a rare primary immunodeficiency disorder that is characterized by defective antibody production and inadequate B cell differentiation. While frequently recurrent respiratory tract infections are the most prominent clinical feature in CVID patients, CVID is a heterogeneous immune deficiency disorder that involves many systems and organs such as lymphoid hyperplasia, autoimmune cytopenia, chronic lung diseases, granulomatous diseases and susceptibility to malignancy. This may lead to delay in diagnosis and immunoglobulin replacement therapy, not being able to receive antibiotics at the appropriate dose and time, chronic inflammation, and therefore secondary amyloidosis. In this case report it is aimed to present a CVID patient with autoimmune complications and developing renal amyloidosis during follow-up.
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Primary Language en
Subjects Medicine
Journal Section Case Report
Authors

Orcid: 0000-0002-9089-5914
Author: Gökhan AYTEKİN (Primary Author)
Institution: MERAM FACULTY OF MEDICINE
Country: Turkey


Orcid: 0000-0002-9596-1773
Author: Fatih ÇÖLKESEN
Institution: MERAM FACULTY OF MEDICINE
Country: Turkey


Orcid: 0000-0002-9596-1773
Author: Eray YILDIZ
Institution: MERAM FACULTY OF MEDICINE
Country: Turkey


Orcid: 0000-0002-8559-2476
Author: Hacı ESEN
Institution: MERAM FACULTY OF MEDICINE
Country: Turkey


Orcid: 0000-0002-0343-0159
Author: Şevket ARSLAN
Institution: MERAM FACULTY OF MEDICINE
Country: Turkey


Supporting Institution none
Project Number -
Thanks -
Dates

Publication Date : April 30, 2020

Bibtex @case report { dtfd693297, journal = {Duzce Medical Journal}, issn = {}, eissn = {1307-671X}, address = {}, publisher = {Duzce University}, year = {2020}, volume = {22}, pages = {67 - 70}, doi = {10.18678/dtfd.693297}, title = {Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications}, key = {cite}, author = {Aytekin, Gökhan and Çölkesen, Fatih and Yıldız, Eray and Esen, Hacı and Arslan, Şevket} }
APA Aytekin, G , Çölkesen, F , Yıldız, E , Esen, H , Arslan, Ş . (2020). Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications . Duzce Medical Journal , 22 (1) , 67-70 . DOI: 10.18678/dtfd.693297
MLA Aytekin, G , Çölkesen, F , Yıldız, E , Esen, H , Arslan, Ş . "Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications" . Duzce Medical Journal 22 (2020 ): 67-70 <https://dergipark.org.tr/en/pub/dtfd/issue/53917/693297>
Chicago Aytekin, G , Çölkesen, F , Yıldız, E , Esen, H , Arslan, Ş . "Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications". Duzce Medical Journal 22 (2020 ): 67-70
RIS TY - JOUR T1 - Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications AU - Gökhan Aytekin , Fatih Çölkesen , Eray Yıldız , Hacı Esen , Şevket Arslan Y1 - 2020 PY - 2020 N1 - doi: 10.18678/dtfd.693297 DO - 10.18678/dtfd.693297 T2 - Duzce Medical Journal JF - Journal JO - JOR SP - 67 EP - 70 VL - 22 IS - 1 SN - -1307-671X M3 - doi: 10.18678/dtfd.693297 UR - https://doi.org/10.18678/dtfd.693297 Y2 - 2020 ER -
EndNote %0 Düzce Tıp Fakültesi Dergisi Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications %A Gökhan Aytekin , Fatih Çölkesen , Eray Yıldız , Hacı Esen , Şevket Arslan %T Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications %D 2020 %J Duzce Medical Journal %P -1307-671X %V 22 %N 1 %R doi: 10.18678/dtfd.693297 %U 10.18678/dtfd.693297
ISNAD Aytekin, Gökhan , Çölkesen, Fatih , Yıldız, Eray , Esen, Hacı , Arslan, Şevket . "Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications". Duzce Medical Journal 22 / 1 (April 2020): 67-70 . https://doi.org/10.18678/dtfd.693297
AMA Aytekin G , Çölkesen F , Yıldız E , Esen H , Arslan Ş . Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications. Duzce Medical Journal. 2020; 22(1): 67-70.
Vancouver Aytekin G , Çölkesen F , Yıldız E , Esen H , Arslan Ş . Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications. Duzce Medical Journal. 2020; 22(1): 67-70.
IEEE G. Aytekin , F. Çölkesen , E. Yıldız , H. Esen and Ş. Arslan , "Renal Amyloidosis in a Common Variable Immune Deficiency Patient with Autoimmune Complications", Duzce Medical Journal, vol. 22, no. 1, pp. 67-70, Apr. 2020, doi:10.18678/dtfd.693297