Symmetrical peripheral polyneuropathy in a severe acute respiratory syndrome coronavirus 2 infection

Abstract

The coronavirus outbreak, which started in December 2019, was announced as a pandemic. We presented a patient with confirmed SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pneumonia developing symmetric polyneuropathy. Some extrapulmonary, primarily neurological clinical presentations of 2019 coronavirus disease (COVID-19) have been reported. A peripheral neuropathy case occurring in a 62-year-old Caucasian male after the SARS-CoV-2 infection is represented by discussing etiopathogenesis. This case might highlight the possible association between the SARS-CoV-2 disease and the nervous system involvement. SARS-CoV-2 infection must be remembered in the differential diagnosis of peripheral neuropathy cases.

Keywords

• Sensory loss
• neuropathic pain
• nervous system
• pandemic
• coronavirus

Project Number

yoktur

Ciddi akut solunum sendromu koronavirüs 2 enfeksiyonunda simetrik periferik polinöropati

Abstract

Aralık 2019'da başlayan koronavirüs salgını pandemi olarak ilan edilmiş olup 2019 koronavirüs hastalığının (COVID-19) ekstrapulmoner, öncelikle nörolojik klinik prezentasyonları bildirilmiştir. Bu olgu sunumunda, simetrik polinöropati gelişen, doğrulanmış SARS-CoV-2 (şiddetli akut solunum sendromu koronavirüs 2) pnömonisi olan bir hastayı sunduk. Bu olgu sunumunda 62 yaşında beyaz bir erkekte SARS-CoV-2 enfeksiyonu sonrası ortaya çıkan bir periferik nöropati olgusu tartışılarak sunulmuştur. Bu vaka, SARS-CoV-2 hastalığı ile sinir sistemi tutulumu arasındaki olası ilişkiyi vurgulayabilir. Periferik nöropati olgularının ayırıcı tanısında SARS-CoV-2 enfeksiyonu mutlaka akılda tutulmalıdır.

Keywords

• Duyu kaybı
• nöropatik ağrı
• sinir sistemi
• pandemi
• koronavirüs

Supporting Institution

yoktur

Project Number

yoktur

References

1. [1] McIntosh K. Coronavirus disease 2019 (COVID-19). UptoDate; 2020 (Available from: https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19#H1354847215)
2. [2] World Health Organization. “WHO director-general's remarks at the media briefing on 2019-nCoV on 11 February 2020”. https://www.who.int/director-general/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020 (01.01.2022).
3. [3] Desforges M, Le Coupanec A, Dubeau P, Bourgouin A, Lajoie L, Dubé M, Talbot PJ. “Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?”. Viruses, 12(1), 14, 2019
4. [4] Tsai LK, Hsieh ST, Chao CC, Chen YC, Lin YH, Chang SC, Chang YC. “Neuromuscular disorders in severe acute respiratory syndrome”. Archives of neurology, 61(11), 1669-1673, 2004.
5. [5] Algahtani H, Subahi A, Shirah B. “Neurological complications of middle east respiratory syndrome coronavirus: a report of two cases and review of the literatüre”. Case reports in neurological medicine, 3502683, 2016.
6. [6] Kim JE, Heo JH, Kim HO, Song SH, Park SS, Park TH, Choi JP. “Neurological complications during treatment of middle east respiratory syndrome”. Journal of Clinical Neurology, 13(3), 227-233, 2017.
7. [7] Zhou C, Wu L, Ni F, Ji W, Wu J, Zhang H. “Critical illness polyneuropathy and myopathy: a systematic review”. Neural regeneration research, 9(1), 101, 2014.
8. [8] Vriesendorp FJ. Guillain-Barré syndrome in adults: clinical features and diagnosis. UpToDate. Waltham, MA: UpToDate, 2017. (Available from: https://www.uptodate.com/contents/guillain-barre-syndrome-in-adults-clinical-features-and-diagnosis