Central Giant Cell Granuloma Masquerading a Radicular Cyst: Case Report

Abstract

Central giant cell granuloma is a benign and reactive intraosseous lesion. It is generally localized in the anterior mandibular region. However, it may be localized in the periradicular region of a vital or non-vital tooth. Periradicular central giant cell granulomas may be misdiagnosed as periapical inflammatory dental lesions such as radicular cysts or cronic apical paradontitis on radiographic or clinical examination. In this case report, a periradicular central giant cell granuloma which is localized in the right maxillary premolar region is presented and the importance of differential diagnosis is discussed

Keywords

• central giant cell granuloma, giant cell granuloma, radicular cyst, radicular patology

RADİKÜLER KİST GÖRÜNÜMLÜ SANTRAL DEV HÜCRELİ GRANÜLOMA: VAKA RAPORU

Abstract

Santral dev hücreli granüloma reaktif ve benign potansiyele sahip kemik içi bir lezyondur. Genellikle alt çene anterior bölgede ortaya çıkan lezyon nadir olarak dişlerin periapikal alanında ortaya çıkabilmektedir. Periradiküler santral dev hücreli granülomalar semptomsuz olarak kendilerini gösterebilmekte ve periradiküler inflamatuar durumlarla radiküler kist, kronik apikal paradontitis klinik ve radyografik olarak karışabilmektedir. Bu vaka raporunda sağ üst premolar bölgede periapikal bölgede ortaya çıkan bir santral dev hücreli granüloma vakası sunulmuş ve klinik ayırıcı tanıdaki önemi tartışılmıştır.

Keywords

• santral dev hücreli granüloma, dev hücreli granüloma, radiküler kist, radiküler patoloji

References

1. 1- Neville BW, Dam DD, Allen CM, Bouquot JE: Oral and Maxillofacial Pathology. 3rd Edition. Philadelphia: WB Saunders co., 2009: pp 626.,
2. 2- Jaffe HL. Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibrooseous) dysplasia of the jawbones. Oral Surg Oral Med Oral Pathol. 1953;6:159-75.
3. 3- Chuong R, Kaban LB, Kozakewich H, Perez-Atayde A. Central giant cell lesions of the jaws: a clinicopathologic study. J Oral Maxillofac Surg. 1986;44:708-13.
4. 4- Lombardi T, Bischof M, Nedir R, Vergain D, Galgano C, Samson J, Küffer R. Periapical central giant cell granuloma misdiagnosed as odontogenic cyst. Int Endod J. 2006 Jun;39(6):510-5.
5. 5- Kumar B, Khambete N. Endodontic misdiagnosis of periapical central giant cell granuloma: Report of case with 2 years followup. Saudi Endod J. 2012;2:95-9
6. 6- Seifi S., Fouroghi R. Central giant cell granuloma: a potential endodontic misdiagnosis. Iranian Endodontic Journal. 2009;4:158-60
7. 7- Unal M, Karabacak T, Vayisoğlu Y, Bağiş HE, Pata YS, Akbaş Y. Central giant cell reparative granuloma of the mandible caused by a molar tooth extraction: special reference to the maneuver of drilling the surgical field. Int J Pediatr Otorhinolaryngol. 2006;70:745-8.
8. 8- De Lange J, Van den Akker HP. Clinical and radiological features of central giantcell lesions of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:464- 70.

9. 9- Dahlkemper P, Wolcott JF, Pringle GA, Hicks ML. Periapical central giant cell granuloma: a potential endodontic misdiagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:739-45.
10. 10- Nary Filho H, Matsumoto MA, Fraga SC, Gonçales ES, Sérvulo F. Periapical radiolucency mimicking an odontogenic cyst. Int Endod J. 2004;37:337-44.
11. 11- Martin LR. Systemic approach to endodontic diagnosis- a must! A case report. Clinical Preventive Dentistry 1982;4:25-7
12. 12- Sykaras SN. Central giant cell granuloma: report of a case. Int Endod J. 1981;14:185-7.
13. 13- Glickman GN. Central giant cell granuloma associated with a non-vital tooth: a case report. Int Endod J. 1988;21:224-30
14. 14- Waldron CA, Shafer WG. The central giant cell reparative granuloma of the jaws. An analysis of 38 cases. Am J Clin Pathol. 1966;45:437-47.
15. 15- Andersen L, Fejerskov O, Philipsen HP. Oral giant cell granulomas. A clinical and histological study of 129 new cases. Acta Pathol Microbiol Scand A. 1973;81:606-16.
16. 16- Eisenbud L, Stern M, Rothberg M, Sachs SA. Central giant cell granuloma of the jaws: experiences in the management of thirtyseven cases. J Oral Maxillofac Surg. 1988;46:376-84.