Peripheral Ossifyineg Fibroma: Clinical and Histopathological evaluation of 50 Cases

Abstract

The peripheral ossifying fibroma is a reactivefocal overgrowth occuring on the gingiva. Theetiology of this gingival overgrowth is uncertain,but periodontal ligament origin has been suggested.The peripheral ossifying fibroma exhibits a peakincidence between the second and third decade.Females are affected more frequently. The anteriormaxillary region is the most common localizationfor the peripheral ossifying fibroma. Well-defined,solitary mass may be ulcerated. The histologicalappearance of peripheral ossifying fibroma ischaracterized by highly cellular connective tissueand randomly dispersed foci of calcifications. Aseries of 50 cases of peripheral ossifying fibromawas analyzed both clinically and histologically. As aconclusion, the lesions that have different clinicalfeatures also show different histomorphologicalfeatures

Keywords

• peripheral ossifying fibroma, calcifying fibrous epulis

PERİFERAL OSSİFİYE FİBROM: 50 VAKALIK SERİDE KLİNİK VE HİSTOPATOLOJİK DEĞERLENDİRME

Abstract

Periferal ossifiye fibrom, dişetinde gelişen,reaktif, lokalize bir doku büyümesidir. Periodontalligamentten geliştiği düşünülen bu reaktif dokubüyümesine neden olan etyolojik faktör kesinolarak tanımlanamamıştır. Sıklıkla genç erişkinlerde, 2. ve 3. dekatlarda ve daha çok kadınlardaortaya çıkar. Maksiller anterior bölge en sıkgörüldüğü lokalizasyondur. Klinik olarak genelde küçük, iyi s›n›rl›, mukozadan kabar›k. Lezyonun histolojisinde, çok katl› yass› epitel ile örtülü, fibroblastik bağ doku zemininde mineralize yap›lar yer almaktad›r. Periferal ossifiye fibrom tan›s› alm›ş toplam 50 lezyon, klinik ve histomorfolojik özellikleri aç›s›ndan yeniden gözden geçirilmiş ve farkl› klinik özelliklere sahip lezyonlar›n birbirlerinden farkl› histolojik özellikler sergiledikleri saptanm›şt›r. Lezyonlar›n bulunduğu farkl› gelişim evrelerine göre farkl› histomorfolojik özellikler gösterdiği ve zaman içinde olgunlaşt›kça lezyonlar›n hücreden fakir, kollajen liflerden ve geniş trabeküler osteid yap›lardan zengin hale geldiği saptanm›şt›r.

Keywords

• Periferal ossifiye fibrom,kalsifiye fibröz epulis

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