Research Article
BibTex RIS Cite
Year 2022, Volume: 49 Issue: 3, 120 - 124, 31.12.2022
https://doi.org/10.52037/eads.2022.0038

Abstract

References

  • 1. Hedin CA, Larsson A. The ultrastructure of the gingival epithelium in smoker’s melanosis. J Periodont Res. 1984; 19: 177–190.
  • 2. Halaban R, Cheng E, Svedine S, Aron R, Hebert DN. Proper folding and endoplasmic reticulum to golgi transport of tyrosinase are induced by its substrates, DOPA and tyrosine. J Biol Chem. 2001; 276: 11933–11938.
  • 3. Gupta G. The labial melanotic macule. A review of 79 cases. Br. Dent. Dermatologyc. 1964; 136: 772-75.
  • 4. Tamizi M, Taheri M. Treatment of severe physiologic gingival pigmentation with free gingival autograft. Quintessence. Int. 1996; 27:555-8.
  • 5. Steigmann S. The relation between physiologic pigmen- tation of the skin and the oral mucosa in Yemenite Jews. Oral Surg. 1965; 19: 32–38.
  • 6. Axell T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. Scand J Dent Res. 1982; 90: 434–442.
  • 7. Araki S, Murata K, Ushio K, Sakai R. Dose response relationship between tobacco consumption and melanin pigmentation in the attached gingiva. Arch Environm Health 1983; 38:6: 375–8.
  • 8. Hedin CA, Axell T. Oral melanin pigmentation in 467 Thai and Malaysian people with special emphasis on smoker’s melanosis. J Oral Pathol Med 1991; 20:8–12.
  • 9. Ünsal E, Paksoy C, Soykan E, Elhan AH, Sahin M: Oral melanin pigmentation related to smoking in a Turkish population. Community Dent Oral Epidemiol 2001; 29: 272–7.
  • 10. Sarswathi TR, Kumar SN, Kavitha KM. Oral melanin pigmentation in smoked and smokeless tobacco users in India. Clinico-pathological study. Indian J Dent Res. 2003; 14: 101–106.
  • 11. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. 2017 WORLD WORKSHOP
  • 12. Hedin CA, Pindborg JJ, Axell T. Disappearance of smoker’s melanosis after reducing smoking. J Oral Pathol Med 1993; 22:228–30.
  • 13. Uysal MA, Kadakal F, Karşidağ C, Bayram NG, Uysal O, Yilmaz V. Fagerström test for nicotine dependence: reliability in a Turkish sample and factor analysis. Tuberk Toraks 2004; 52:115-121.
  • 14. Moolchan ET, Radzius A, Epstein DH, Uhl G, Gorelick DA Cadet JL, Henningfield JE. The Fagerstrom Test for Nicotine Dependence and the Diagnostic Interview Schedule: do they diagnose the same smokers? Addict Behav. 2002; 27:101-13.
  • 15. Bergström J, Persson L, Preber H. Influence of cigarette smoking on vascular reaction during experimental gingivitis. Scand J Dent Res 1988; 21:668–76.
  • 16. Wood NK, Goaz PW. Intraoral brownish, bluish or black conditions. In: Differential diagnosis of oral and maxillofacial Lesions. St. Louis: Mosby; 1997. p. 182–208.
  • 17. Hanioka T, Tanaka K, Ojima M, Yuuki K. Association of melanin pigmentation in the gingiva of children with parents who smoke. Pediatrics. 2005;116(2): e186-90.
  • 18. Moravej-Salehi E, Moravej-Salehi E, Hajifattahi F. Relationship of Gingival Pigmentation with Passive Smoking in Women. Tanaffos. 2015;14(2):107-114.

Evaluation of the Relationship Between Gingival Pigmentation and Smoking

Year 2022, Volume: 49 Issue: 3, 120 - 124, 31.12.2022
https://doi.org/10.52037/eads.2022.0038

Abstract

The abnormal deposition of melanin in the oral mucosa results in melanin pigmentation. The gingiva that has undergone keratinization is most affected. Gingival discoloration may be caused by physiologic or pathological reasons. Melanocytic lesions or melanocytic pigmentations induced by an excessive deposition of melanin in the basal and suprabasal layers of the epithelium are the most common pigmentations of the gingiva. Smoking has been associated to oral melanin pigmentation, particularly in the anterior gingiva. The Fagerstrom Test for Nicotine Dependence is the most used instrument for assessing smoking addiction (FTND). The Fagerstrom Test for Nicotine Dependence (FTND) consists of six questions, with a distinct score assigned to each. Our study comprised 255 individuals over the age of 18 who were smokers, did not use drugs, did not have any systemic illnesses that could contribute to pigmentation, and did not have any active infectious infections. The Hedin scale was used to assess the pigmentation levels of the subjects. The Fagerstrom Test for Nicotine Dependence was used to diagnose the kind of cigarette addiction exhibited by the subjects. Using the Fagerstrom questionnaire, we observed that pigmentation was more common as smoking tendency inreased.

References

  • 1. Hedin CA, Larsson A. The ultrastructure of the gingival epithelium in smoker’s melanosis. J Periodont Res. 1984; 19: 177–190.
  • 2. Halaban R, Cheng E, Svedine S, Aron R, Hebert DN. Proper folding and endoplasmic reticulum to golgi transport of tyrosinase are induced by its substrates, DOPA and tyrosine. J Biol Chem. 2001; 276: 11933–11938.
  • 3. Gupta G. The labial melanotic macule. A review of 79 cases. Br. Dent. Dermatologyc. 1964; 136: 772-75.
  • 4. Tamizi M, Taheri M. Treatment of severe physiologic gingival pigmentation with free gingival autograft. Quintessence. Int. 1996; 27:555-8.
  • 5. Steigmann S. The relation between physiologic pigmen- tation of the skin and the oral mucosa in Yemenite Jews. Oral Surg. 1965; 19: 32–38.
  • 6. Axell T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. Scand J Dent Res. 1982; 90: 434–442.
  • 7. Araki S, Murata K, Ushio K, Sakai R. Dose response relationship between tobacco consumption and melanin pigmentation in the attached gingiva. Arch Environm Health 1983; 38:6: 375–8.
  • 8. Hedin CA, Axell T. Oral melanin pigmentation in 467 Thai and Malaysian people with special emphasis on smoker’s melanosis. J Oral Pathol Med 1991; 20:8–12.
  • 9. Ünsal E, Paksoy C, Soykan E, Elhan AH, Sahin M: Oral melanin pigmentation related to smoking in a Turkish population. Community Dent Oral Epidemiol 2001; 29: 272–7.
  • 10. Sarswathi TR, Kumar SN, Kavitha KM. Oral melanin pigmentation in smoked and smokeless tobacco users in India. Clinico-pathological study. Indian J Dent Res. 2003; 14: 101–106.
  • 11. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. 2017 WORLD WORKSHOP
  • 12. Hedin CA, Pindborg JJ, Axell T. Disappearance of smoker’s melanosis after reducing smoking. J Oral Pathol Med 1993; 22:228–30.
  • 13. Uysal MA, Kadakal F, Karşidağ C, Bayram NG, Uysal O, Yilmaz V. Fagerström test for nicotine dependence: reliability in a Turkish sample and factor analysis. Tuberk Toraks 2004; 52:115-121.
  • 14. Moolchan ET, Radzius A, Epstein DH, Uhl G, Gorelick DA Cadet JL, Henningfield JE. The Fagerstrom Test for Nicotine Dependence and the Diagnostic Interview Schedule: do they diagnose the same smokers? Addict Behav. 2002; 27:101-13.
  • 15. Bergström J, Persson L, Preber H. Influence of cigarette smoking on vascular reaction during experimental gingivitis. Scand J Dent Res 1988; 21:668–76.
  • 16. Wood NK, Goaz PW. Intraoral brownish, bluish or black conditions. In: Differential diagnosis of oral and maxillofacial Lesions. St. Louis: Mosby; 1997. p. 182–208.
  • 17. Hanioka T, Tanaka K, Ojima M, Yuuki K. Association of melanin pigmentation in the gingiva of children with parents who smoke. Pediatrics. 2005;116(2): e186-90.
  • 18. Moravej-Salehi E, Moravej-Salehi E, Hajifattahi F. Relationship of Gingival Pigmentation with Passive Smoking in Women. Tanaffos. 2015;14(2):107-114.
There are 18 citations in total.

Details

Primary Language English
Subjects Dentistry
Journal Section Original Research Articles
Authors

Kardelen Başol 0000-0002-9320-535X

Elif Ünsal 0000-0002-7843-6088

Mehmet Esat Başol This is me 0000-0002-1649-2359

Candan Paksoy 0000-0002-6961-5172

Ali Ursavaş This is me 0000-0002-4544-9739

Sena Karacan Çelebi 0000-0002-9382-2200

Publication Date December 31, 2022
Submission Date October 30, 2022
Published in Issue Year 2022 Volume: 49 Issue: 3

Cite

Vancouver Başol K, Ünsal E, Başol ME, Paksoy C, Ursavaş A, Karacan Çelebi S. Evaluation of the Relationship Between Gingival Pigmentation and Smoking. EADS. 2022;49(3):120-4.