Antimicrobial and Antimutagenic Properties of Physalis alkekengi L.

Abstract

The application of herbal medicines is increasing day by day. Some bioactive compounds of medicinal plant have various therapeutic effects. In this study, the antimicrobial and antimutagenic of the Physalis alkekengi, used for various therapeutic effects were investigated. The methanol and water extracts of Physalis alkekengi L. were analyzed antimutagenic and antimicrobial activity. In the findings obtained, we determined that Physalis alkekengi L. has antimutagenic activity, especially at a concentration of 75 µL. In additional, antimicrobial activity of methanol and water extracts from of P. alkekengi fruits was examined against human pathogenic Gram positive and Gram-negative bacteria and yeasts. Methanol and water extracts of Physalis alkekengi L. showed varying degrees of inhibitor effects (15 mm-40 mm, 20mm-30 mm respectively) on the growth of the diverse pathogenic strains tested. Methanol extract of Physalis alkekengi L. showed higher activity than commercial antibiotics in S. epidermis, B. cereus, P. vulgaris and P. aeruginosa (30 mm, 40 mm, 25 mm, 30 mm, respectively). These findings indicated that the fruit extract of P. alkekengi L. has potential application as an ingredient in pharmaceuticals.

Keywords

• P. alkekengi L.
• Antimutagenic
• SCE
• Antimicrobial.

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