Leptin and Metabolic Effects

Abstract

Leptin is a metabolic hormone secreted from adipose tissue, also called satiety hormone. This hormone plays an important role in the regulation of body weight and energy homeostasis. Studies have shown that deficiency or excess of this hormone causes many metabolic changes in our body (such as obesity, type 2 diabetes, cardiovascular diseases, cancer). In this review, the general properties of leptin and its effect on these metabolic diseases were examined.

Keywords

• leptin
• metabolic diseases
• obesity
• diabetes mellitus
• cardiovascular diseases

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