Botulinum Toxin Treatment for Refractory Sialorrhea in a Geriatric Patient with Parkinson’s and Alzheimer’s Disease: A Case Report

Abstract

Sialorrhea, otherwise known as hypersalivation, is a symptom frequently observed in neurodegenerative diseases such as Parkinson's disease and dementia. This condition can have a significant impact on the patient's social life and quality of life. Pharmacological treatments frequently prove to be either ineffective or intolerable for elderly patients. In this case report, the efficacy and safety of botulinum toxin administration are presented in a 78-year-old male patient with diagnoses of Parkinson's and Alzheimer's disease who presented with complaints of profuse salivation from the mouth and nose.

Keywords

• Sialore
• Parkinson's disease
• Alzheimer's disease
• botulinum toxin
• geriatrics

Supporting Institution

No financial support was received from any institution for this study.

Ethical Statement

All personal data were kept confidential and used only for scientific purposes.

Thanks

There are no individuals or institutions to acknowledge for this study.

Parkinson ve Alzheimer Hastalığı Olan Geriatrik Bir Hastada Refrakter Sialore Tedavisinde Botulinum Toksin Uygulaması: Olgu Sunumu

Abstract

Sialore (hipersalivasyon), özellikle Parkinson hastalığı ve demans gibi nörodejeneratif hastalıklarda sık görülen, hastanın sosyal yaşamını ve yaşam kalitesini ciddi biçimde bozan bir semptomdur. Farmakolojik tedaviler çoğu zaman yetersiz kalmakta veya yaşlı hastalarda tolere edilememektedir. Bu olgu sunumunda, Parkinson ve Alzheimer tanıları bulunan, ağız ve burundan yoğun tükürük akması şikâyeti ile başvuran 78 yaşındaki erkek hastada botulinum toksin uygulamasının etkinliği ve güvenilirliği sunulmuştur.

Keywords

• Sialore
• Parkinson hastalığı
• Alzheimer hastalığı
• Botulinum toksin
• Geriatri

Supporting Institution

Bu çalışma için herhangi bir kurumdan finansal destek alınmamıştır.

Ethical Statement

Katılımcıların kimlik bilgileri gizli tutulmuş ve yalnızca bilimsel amaçlarla kullanılmıştır.

Thanks

Bu çalışmaya katkı sağlayan kişi veya kurum bulunmamaktadır.

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