Research Article
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Year 2021, Volume: 2 Issue: 4, 231 - 241, 03.01.2022

Abstract

Kardiyovasküler kalp hastalıkları gelişmiş ülkelerde en sık görülen mortalite ve morbidite nedenidir. Retrospektif çalışmamızda akut anterior miyokard enfarktüsü ile hastaneye başvuran ve primer perkütan koroner girişim ile reperfüzyon tedavisi uygulanan hastaları derledik. Bu hastaları SYNTAX, klinik SYNTAX ve rezidüel SYNTAX skoru ile değerlendirdik ve bunların intrakardiyak defibrilatör cihazı (ICD) implantasyonunu öngörmedeki rolünü araştırdık. Çalışmaya, 2011-2013 yılları arasında primer perkütan koroner girişimi olan akut miyokard enfarktüslü 345 hasta dahil edildi. Anjiyografik görüntüler incelendi ve SYNTAX, klinik SYNTAX ve rezidüel SYNTAX skorları hesaplandı. Hastaların 52'sine ICD implantasyonu uygulandı. Bu hastalarda tek değişkenli analiz ile ortalama yaş, diabetes mellitus, hipertansiyon, hiperlipidemi prevalansı, sigara içme oranı, glomerüler filtrasyon hızı, miyokard enfarktüsünde tromboliz akış skoru, SYNTAX skoru, klinik SYNTAX skoru ve rezidüel SYNTAX skoru anlamlı olarak daha yüksekti. Çok değişkenli lojistik regresyon analizi ile ejeksiyon fraksiyonu (EF) ve üç SYNTAX puanı anlamlı kabul edildi. 3 aylık takipten sonra, ICD uygulamasının tahmininin, akut anterior MI hastaları ile ilk başvuruda hesaplanan EF, SYNTAX, klinik SYNTAX ve rezidüel SYNTAX skorları ile hesaplanabileceğini gördük. Düşük EF ve yüksek SYNTAX skoru olan hastalarda yakın takip gerektiğini düşünüyoruz.
Anahtar Kelimeler: Akut anterior miyokard enfarktüsü, SYNTAX, Clinical SYNTAX, Rezidüel SYNTAX skorları, ICD.

References

  • 1. Petrovic L, Chhabra L. Selecting A Treatment Modality In Acute Coronary Syndrome. StatPearls. Treasure Island (FL)2021.
  • 2. Serkan Karahan, Fahrettin Katkat, Okuyan E. Markers for creatinine height after percutaneous coronary intervention in patients with normal renal function. Ann Clin Anal Med. 2020. DOI 10.4328/ACAM.20289.
  • 3. Melillo E, Carbone A, Rago A, Papa AA, A DO, Nigro G, et al. Update on Direct Oral Anticoagulants in Atrial Fibrillation Patients Undergoing Cardiac Interventional Procedures: From Clinical Trials to Real-World Evidence. J Cardiovasc Pharmacol. 2020;75(3):185-99.
  • 4. Karahan S, Okuyan E. Systemic Inflammatory Index and Platelet-to-Lymphocyte Ratio Predicted Mortality in patients with Acute Myocardial Infarction. Experimental Applied Medical Science. 2021;2(2):146-53.
  • 5. Dokuyucu R, Gogebakan B, Yumrutas O, Bozgeyik I, Gokce H, Demir T. Expressions of TRPM6 and TRPM7 and histopathological evaluation of tissues in ischemia reperfusion performed rats. Ren Fail. 2014;36(6):932-6.
  • 6. Hamm CW. Risk stratifying acute coronary syndromes: gradient of risk and benefit. Am Heart J. 1999;138(1 Pt 2):S6-11.
  • 7. Gold MR, Linde C, Abraham WT, Gardiwal A, Daubert JC. The impact of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in mild heart failure. Heart Rhythm. 2011;8(5):679-84.
  • 8. Lee J, Ahn JM, Kim JH, Jeong YJ, Hyun J, Yang Y, et al. Prognostic Effect of the SYNTAX Score on 10-Year Outcomes After Left Main Coronary Artery Revascularization in a Randomized Population: Insights From the Extended PRECOMBAT Trial. J Am Heart Assoc. 2021;10(14):e020359.
  • 9. Grubb A, Bjork J, Lindstrom V, Sterner G, Bondesson P, Nyman U. A cystatin C-based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft-Gault formula. Scand J Clin Lab Invest. 2005;65(2):153-62.
  • 10. Foo CY, Reidpath DD, Chaiyakunapruk N. The effect of door-to-balloon delay in primary percutaneous coronary intervention on clinical outcomes of STEMI: a systematic review and meta-analysis protocol. Syst Rev. 2016;5(1):130.
  • 11. Otaki Y, Watanabe T, Goto J, Wanezaki M, Kato S, Tamura H, et al. Association between thrombolysis in myocardial infarction grade and clinical outcome after emergent percutaneous coronary intervention in patients with acute myocardial infarction who have suffered out-of-hospital cardiac arrest: the Yamagata AMI registry. Heart Vessels. 2021.
  • 12. Dauw J, Martens P, Deferm S, Bertrand P, Nijst P, Hermans L, et al. Left ventricular function recovery after ST-elevation myocardial infarction: correlates and outcomes. Clin Res Cardiol. 2021.
  • 13. Hasin T, Davarashvili I, Michowitz Y, Farkash R, Presman H, Glikson M, et al. Association of Guideline-Based Medical Therapy with Malignant Arrhythmias and Mortality among Heart Failure Patients Implanted with Cardioverter Defibrillator (ICD) or Cardiac Resynchronization-Defibrillator Device (CRTD). J Clin Med. 2021;10(8).
  • 14. Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA, 3rd, Freedman RA, Gettes LS, et al. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2013;61(3):e6-75.
  • 15. Dunn AN, Huded C, Raymond R, Lincoff AM, Bajzer C, Kapadia S, et al. Successful modeling of long term outcomes in end-stage renal disease patients undergoing percutaneous coronary intervention with drug-eluting stents. Catheter Cardiovasc Interv. 2021.
  • 16. Kristic I, Crncevic N, Runjic F, Capkun V, Polasek O, Matetic A, et al. ACEF performed better than other risk scores in non-ST-elevation acute coronary syndrome during long term follow-up. BMC Cardiovasc Disord. 2021;21(1):70.
  • 17. Costa F, Ariotti S, Valgimigli M, Kolh P, Windecker S, Task Force on Myocardial Revascularization of the European Society of C, et al. Perspectives on the 2014 ESC/EACTS Guidelines on Myocardial Revascularization : Fifty Years of Revascularization: Where Are We and Where Are We Heading? J Cardiovasc Transl Res. 2015;8(4):211-20.

The Role of Syntax Scores in Predicting Intracardiac Defibrillator Implantation in Acute Anterior Myocardial Infarction

Year 2021, Volume: 2 Issue: 4, 231 - 241, 03.01.2022

Abstract

Cardiovascular heart diseases are the most common mortality and morbidity cause in developed countries. In our retrospective study we searched for patients who admitted to hospital with acute anterior myocardial infarction that underwent reperfusion therapy with primary percutan coronary intervention. We assessed these patients with SYNTAX, clinical SYNTAX and residual SYNTAX score and investigate of those to predict intracardiac defibrillator device (ICD) implantation. 345 patients with acute myocardial infarction who received primary percutan coronary invention, through 2011-2013 years, were included. Angiographic pictures are investigated and SYNTAX, clinical SYNTAX ve residual SYNTAX scores were calculated. 52 of the patients had ICD implantation. In these patients, with one variable analysis, mean age, diabetes mellitus, hypertension, hyperlipidemia prevalence, smoking rate, glomerular filtration rate, thrombolysis in myocardial infarction flow score, SYNTAX score, clinical SYNTAX score and residual SYNTAX score were significantly higher. With the multiple variable logistic regression analysis ejection fraction (EF) and three SYNTAX score was considered significant. We found that after 3-month follow up, prediction of ICD implementation could be reckoned with EF, SYNTAX, clinical SYNTAX and residual SYNTAX scores calculated at first admission with acute anterior MI patients. We recommend that close follow is needed for patients with low EF and high SYNTAX score.
Key Words: Acute anterior myocardial infarction, SYNTAX, Clinical SYNTAX, Residual SYNTAX scores, ICD.

References

  • 1. Petrovic L, Chhabra L. Selecting A Treatment Modality In Acute Coronary Syndrome. StatPearls. Treasure Island (FL)2021.
  • 2. Serkan Karahan, Fahrettin Katkat, Okuyan E. Markers for creatinine height after percutaneous coronary intervention in patients with normal renal function. Ann Clin Anal Med. 2020. DOI 10.4328/ACAM.20289.
  • 3. Melillo E, Carbone A, Rago A, Papa AA, A DO, Nigro G, et al. Update on Direct Oral Anticoagulants in Atrial Fibrillation Patients Undergoing Cardiac Interventional Procedures: From Clinical Trials to Real-World Evidence. J Cardiovasc Pharmacol. 2020;75(3):185-99.
  • 4. Karahan S, Okuyan E. Systemic Inflammatory Index and Platelet-to-Lymphocyte Ratio Predicted Mortality in patients with Acute Myocardial Infarction. Experimental Applied Medical Science. 2021;2(2):146-53.
  • 5. Dokuyucu R, Gogebakan B, Yumrutas O, Bozgeyik I, Gokce H, Demir T. Expressions of TRPM6 and TRPM7 and histopathological evaluation of tissues in ischemia reperfusion performed rats. Ren Fail. 2014;36(6):932-6.
  • 6. Hamm CW. Risk stratifying acute coronary syndromes: gradient of risk and benefit. Am Heart J. 1999;138(1 Pt 2):S6-11.
  • 7. Gold MR, Linde C, Abraham WT, Gardiwal A, Daubert JC. The impact of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in mild heart failure. Heart Rhythm. 2011;8(5):679-84.
  • 8. Lee J, Ahn JM, Kim JH, Jeong YJ, Hyun J, Yang Y, et al. Prognostic Effect of the SYNTAX Score on 10-Year Outcomes After Left Main Coronary Artery Revascularization in a Randomized Population: Insights From the Extended PRECOMBAT Trial. J Am Heart Assoc. 2021;10(14):e020359.
  • 9. Grubb A, Bjork J, Lindstrom V, Sterner G, Bondesson P, Nyman U. A cystatin C-based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft-Gault formula. Scand J Clin Lab Invest. 2005;65(2):153-62.
  • 10. Foo CY, Reidpath DD, Chaiyakunapruk N. The effect of door-to-balloon delay in primary percutaneous coronary intervention on clinical outcomes of STEMI: a systematic review and meta-analysis protocol. Syst Rev. 2016;5(1):130.
  • 11. Otaki Y, Watanabe T, Goto J, Wanezaki M, Kato S, Tamura H, et al. Association between thrombolysis in myocardial infarction grade and clinical outcome after emergent percutaneous coronary intervention in patients with acute myocardial infarction who have suffered out-of-hospital cardiac arrest: the Yamagata AMI registry. Heart Vessels. 2021.
  • 12. Dauw J, Martens P, Deferm S, Bertrand P, Nijst P, Hermans L, et al. Left ventricular function recovery after ST-elevation myocardial infarction: correlates and outcomes. Clin Res Cardiol. 2021.
  • 13. Hasin T, Davarashvili I, Michowitz Y, Farkash R, Presman H, Glikson M, et al. Association of Guideline-Based Medical Therapy with Malignant Arrhythmias and Mortality among Heart Failure Patients Implanted with Cardioverter Defibrillator (ICD) or Cardiac Resynchronization-Defibrillator Device (CRTD). J Clin Med. 2021;10(8).
  • 14. Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA, 3rd, Freedman RA, Gettes LS, et al. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2013;61(3):e6-75.
  • 15. Dunn AN, Huded C, Raymond R, Lincoff AM, Bajzer C, Kapadia S, et al. Successful modeling of long term outcomes in end-stage renal disease patients undergoing percutaneous coronary intervention with drug-eluting stents. Catheter Cardiovasc Interv. 2021.
  • 16. Kristic I, Crncevic N, Runjic F, Capkun V, Polasek O, Matetic A, et al. ACEF performed better than other risk scores in non-ST-elevation acute coronary syndrome during long term follow-up. BMC Cardiovasc Disord. 2021;21(1):70.
  • 17. Costa F, Ariotti S, Valgimigli M, Kolh P, Windecker S, Task Force on Myocardial Revascularization of the European Society of C, et al. Perspectives on the 2014 ESC/EACTS Guidelines on Myocardial Revascularization : Fifty Years of Revascularization: Where Are We and Where Are We Heading? J Cardiovasc Transl Res. 2015;8(4):211-20.
There are 17 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Barış Kavvasoğlu

Mustafa Kurt

Sefa Akdemir This is me

Gamze Kavvasoglu This is me

Early Pub Date December 29, 2021
Publication Date January 3, 2022
Published in Issue Year 2021 Volume: 2 Issue: 4

Cite

Vancouver Kavvasoğlu B, Kurt M, Akdemir S, Kavvasoglu G. The Role of Syntax Scores in Predicting Intracardiac Defibrillator Implantation in Acute Anterior Myocardial Infarction. Exp Appl Med Sci. 2022;2(4):231-4.

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