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Leptin and Metabolic Effects

Year 2022, Volume: 3 Issue: 3 - Experimental and Applied Medical Science Vol:3, Issue:3 [en], 403 - 409, 31.12.2022

Abstract

Leptin is a metabolic hormone secreted from adipose tissue, also called satiety hormone. This hormone plays an important role in the regulation of body weight and energy homeostasis. Studies have shown that deficiency or excess of this hormone causes many metabolic changes in our body (such as obesity, type 2 diabetes, cardiovascular diseases, cancer). In this review, the general properties of leptin and its effect on these metabolic diseases were examined.

References

  • 1. Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994; 372:425-32.
  • 2. Pico C, Palou M. Leptin and metabolic programming. Nutrients. 2022; 14 ; 114
  • 3. Aslan K, Serdar Z, Tokullugil A. Multifonksiyonel hormon: Leptin. Uludağ Üniversitesi Tıp Fakültesi Dergisi. 2004; 30 (2); 113-11.
  • 4. Ghadge AA, Khaire AA. Leptin as a predictive marker for metabolic syndrome. Cytokine. 2019;121:154735. Koca et al.
  • 5. Keleş V, Büyükgüzel K, Büyükgüzel E. Leptin ve metabolik düzenlemedeki rolü. Türkiye Diyabet ve Obezite Dergisi. 2018; 1 : 17-22.
  • 6. Uzun T, Bayraktar B. Leptin hormonunun bazı fizyolojik sistemler üzerindeki etkisinin incelenmesi. Bayburt Üniversitesi Fen Bilimleri Dergisi. 2019; 2(1) ; 104-109.
  • 7. Zhou Y, Liangyou R. Leptin signaling and leptin resistance. Front Med. 2013 ; 7(2) : 207-222.
  • 8. Mantzoros CS, Magkos F, Brinkoetter M, et al. Leptin in human physiology and pathophysiology. Am J Physiol Endocrinol Metab. 2011; 301(4):E567–E584.
  • 9. Gültürk S, Demirkaşık A. Leptin ve diyabet. Cumhuriyet Üniversitesi Tıp Fakültesi Dergisi. 2007; 29: 35-40.
  • 10. Comba A, Mert H, Comba B. Leptin ve metabolik etkileri. Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Dergisi. 2014;25(3) : 87-91.
Year 2022, Volume: 3 Issue: 3 - Experimental and Applied Medical Science Vol:3, Issue:3 [en], 403 - 409, 31.12.2022

Abstract

References

  • 1. Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994; 372:425-32.
  • 2. Pico C, Palou M. Leptin and metabolic programming. Nutrients. 2022; 14 ; 114
  • 3. Aslan K, Serdar Z, Tokullugil A. Multifonksiyonel hormon: Leptin. Uludağ Üniversitesi Tıp Fakültesi Dergisi. 2004; 30 (2); 113-11.
  • 4. Ghadge AA, Khaire AA. Leptin as a predictive marker for metabolic syndrome. Cytokine. 2019;121:154735. Koca et al.
  • 5. Keleş V, Büyükgüzel K, Büyükgüzel E. Leptin ve metabolik düzenlemedeki rolü. Türkiye Diyabet ve Obezite Dergisi. 2018; 1 : 17-22.
  • 6. Uzun T, Bayraktar B. Leptin hormonunun bazı fizyolojik sistemler üzerindeki etkisinin incelenmesi. Bayburt Üniversitesi Fen Bilimleri Dergisi. 2019; 2(1) ; 104-109.
  • 7. Zhou Y, Liangyou R. Leptin signaling and leptin resistance. Front Med. 2013 ; 7(2) : 207-222.
  • 8. Mantzoros CS, Magkos F, Brinkoetter M, et al. Leptin in human physiology and pathophysiology. Am J Physiol Endocrinol Metab. 2011; 301(4):E567–E584.
  • 9. Gültürk S, Demirkaşık A. Leptin ve diyabet. Cumhuriyet Üniversitesi Tıp Fakültesi Dergisi. 2007; 29: 35-40.
  • 10. Comba A, Mert H, Comba B. Leptin ve metabolik etkileri. Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Dergisi. 2014;25(3) : 87-91.
There are 10 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Review
Authors

Feride Koca

Leyla Çimen

Early Pub Date December 31, 2022
Publication Date December 31, 2022
Published in Issue Year 2022 Volume: 3 Issue: 3 - Experimental and Applied Medical Science Vol:3, Issue:3 [en]

Cite

Vancouver Koca F, Çimen L. Leptin and Metabolic Effects. Exp Appl Med Sci. 2022;3(3):403-9.

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