Aujeszky Hastalığı Üzerine Bir Derleme

Year 2025, Volume: 4 Issue: 1, 63 - 72, 28.03.2025

Ali Güngör

https://doi.org/10.59312/ebshealth.1606725

Abstract

Aujeszky hastalığı, ya da diğer adıyla Pseudorabies, Suid Alphaherpesvirus 1 tarafından oluşturulan ve domuzlar başta olmak üzere birçok memeli hayvanda enfeksiyonlara yol açan viral bir hastalıktır. Pseudorabies virüsü, Herpesviridae ailesinin Alphaherpesvirinae alt ailesine ait olup, domuzlar bu virüsün doğal konakçısıdır. Enfeksiyon, özellikle domuz yavrularında nörolojik bozukluklara, erişkin dişi domuzlarda ise infertiliteye neden olmaktadır. Virüs, sinir sistemi aracılığıyla yayılarak, enfekte hayvanlar arasında ağız ve burun salgıları yoluyla doğrudan temasla bulaşmaktadır. Aujeszky hastalığı, dünya genelinde büyük ekonomik kayıplara yol açmakta ve özellikle Latin Amerika, Afrika, Asya ve Doğu Avrupa gibi bölgelerde yaygın olarak görülmektedir. Bu derleme makale, Pseudorabies virüsünün etiyolojik özelliklerini, patogenezini, klinik bulgularını, epidemiyolojik yayılımını ve kontrol yöntemlerini incelemektedir.

Keywords

Aujeszky Hastalığı, Pseudorabies Virüsü (PRV), Nöroinvazyon, Etiyoloji, Histopatoloji

A REVİEW ON AUJESZKY'S DİSEASE

Abstract

Aujeszky's disease, also known as Pseudorabies, is a viral infection caused by Suid Alphaherpesvirus 1, which affects many mammalian species, with pigs being the primary host. The Pseudorabies virus belongs to the Alphaherpesvirinae subfamily of the Herpesviridae family, with pigs serving as its natural host. The infection leads to neurological disorders, particularly in piglets, and infertility in adult sows. The virus spreads through the nervous system and is transmitted by direct contact with oral and nasal secretions between infected animals. Aujeszky's disease causes significant economic losses worldwide and remains prevalent, especially in regions such as Latin America, Africa, Asia, and Eastern Europe. This review article examines the etiological characteristics, pathogenesis, clinical manifestations, epidemiological spread, and control methods of the Pseudorabies virus.

Keywords

Aujeszky, Pseudorabies Virus (PRV), Neuroinvasion, Etiology, Histopathology

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