A Rare Maxillary Case of Calcified Epithelial Odontogenic (Pindborg) Tumor in a Young Patient

Year 2024, Volume: 2 Issue: 3, 73 - 75, 30.12.2024

Mahide Büşra Başkan , Merva Soluk Tekkeşin , Meltem Koray

https://doi.org/10.62243/edr.1585589

Abstract

Aim The calcified epithelial odontogenic tumor (CEOT) is a rare, benign lesion, accounting for approximately 1% of odontogenic tumors. The primary treatment involves surgical excision, with a documented recurrence rate of 14%. This case report aims to contribute to the literature by presenting the radiological and histopathological findings, along with the surgical management, of a CEOT located in an unusual area in a female patient under 20 years old.
Case Report An 18-year-old female patient was referred to our clinic due to an incidental lesion located between the left maxillary premolar teeth. A delayed positive response was noted in the cold vitality test performed on asymptomatic, caries-free premolars. Cone beam computed tomography (CBCT) revealed a radiolucent lesion between the premolars, displacing the root of tooth 24 buccally and expanding the palatal cortex, with central radiopacity. Under local anesthesia, a palatal mucoperiosteal flap was raised, and a window was created in the palatal cortex using a surgical bur. The lesion was then enucleated with a curette, and the flap was sutured. Histopathological analysis showed polyhedral tumor cells among large and small calcification islands, confirming a diagnosis of CEOT.
Discussion Although treatment options may vary based on CEOT location and size, enucleation remains the most common approach.
Conclusion Given the high recurrence rate, long-term follow-up is essential. The patient has been followed up every six months, with no recurrence observed over a two-year period.

Keywords

Calcified epithelial odontogenic tumor, Enucleation, Liesegang rings, Maxilla, Pindborg tumor

References

• Wright, J. M., & Soluk Tekkesin, M. (2017). Odontogenic tumors: where are we in 2017 ?. Journal of Istanbul University Faculty of Dentistry, 51(3 Suppl 1), S10–S30.
• Morais, H. G. F., da Silva, W. R., Andrade, A. C. M., Silva, N. S. E., Xerez, M. C., Santos, J. W. M., Germano, A. R., & Costa, A. L. L. (2022). Pindborg tumor associated with a supernumerary tooth: a case report. Autopsy & case reports, 12, e2021358.
• Müller, D., Manojlović, S., Luksić, I., & Grgurević, J. (2012). Calcifying epithelial odontogenic tumor of the maxilla (Pindborg tumor). Collegium antropologicum, 36 Suppl 2, 205–208.
• Misra, S. R., Lenka, S., Sahoo, S. R., & Mishra, S. (2013). Giant pindborg tumor (calcifying epithelial odontogenic tumor): an unusual case report with radiologic-pathologic correlation. Journal of clinical imaging science, 3(Suppl 1), 11.
• Mujib, B. R., Kulkarni, P. G., Lingappa, A., Jahagirdar, A., & Soman, C. (2012). An atypical presentation of Pindborg tumor in anterior maxilla. Dental research journal, 9(4), 495–498.
• Priya, S., Madanagopaal, L. R., & Sarada, V. (2016). Pigmented Pindborg tumor of the maxilla: A case report. Journal of oral and maxillofacial pathology : JOMFP, 20(3), 548.
• Franklin CD, Pindborg JJ. The calcifying epithelial odontogenic tumor: a review and analysis of 113 cases. Oral Surg Oral Med Oral Pathol. 1976; 42(6):753-765.
• Chrcanovic, B. R., & Gomez, R. S. (2017). Calcifying epithelial odontogenic tumor: An updated analysis of 339 cases reported in the literature. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 45(8), 1117–1123.
• Regezi JA, Sciubba JJ, Jordan RC. Oral pathology: clinical pathologic correlations. Elsevier Health Sciences, 2016.
• Kaplan, V., Ciğerim, L., Güzel, M., Bayzed, J., Baş, H. & Böyük, H. M. (2022). Kalsifiye Epitelyal Odontojenik Tümör Oluşumuna Bağlı Olarak Gömülü Kalmış Dişin Cerrahi Tedavi Sonrası Ortodontik Sürdürülmesi. Van Diş Hekimliği Dergisi, 3(2), 31-36.
• Piskadło, T., Brodowski, R., Książek, M., Pakla, P., Dymek, M., Haberko, P., Franczak, J., Stopyra, W., & Lewandowski, B. (2019). Calcifying Epithelial Odontogenic Tumour. Review of the literature and own experience. Developmental period medicine, 23(1), 34–38.