Research Article
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Year 2025, Volume: 8 Issue: 2, 57 - 60, 29.12.2025
https://doi.org/10.46239/ejbcs.1772538

Abstract

References

  • Albayrak FÖ, Özdeniz E, Kurt L, Keleş Y. 2021. Variation of phenolic and pigment composition depending on soil type in three serpentinovag plant species. Int J Second Metabol. 8:1–10. doi:10.21448/ijsm.765645
  • Almeida IF, Fernandes E, Lima JLFC, Valentão P, Andrade PB, Seabra RM, Costa PC, Bahia MF. 2009. Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract. J Med Food. 12:175–183.
  • Álvarez X, Cancela Á, Merchán Y, Sánchez Á. 2021. Anthocyanins, phenolic compounds, and antioxidants from extractions of six Eucalyptus species. Appl Sci. 11:9818. doi:10.3390/app11219818
  • Caponio F, Alloggio V, Gomes T. 1999. Phenolic compounds of virgin olive oil: influence of paste preparation techniques. Food Chem. 64:203–209. doi:10.1016/S0308-8146(98)00146-0
  • Chamali S, Bendaoud H, Bouajila J, Camy S, Saadaoui E, Condoret JS, Romdhane M. 2023. Optimization of accelerated solvent extraction of bioactive compounds from Eucalyptus intertexta using response surface methodology and evaluation of its phenolic composition and biological activities. J Appl Res Med Aromat Plants. 35:100464. doi:10.1016/j.jarmap.2023.100464
  • Çekiç FÖ, Özdeniz E, Öktem M, Kurt L, Keleş Y. 2018. The role of biochemical regulation on the adaptation of gypsophile and gypsovag species. Biochem Syst Ecol. 81:12–16. doi:10.1016/j.bse.2018.09.007
  • Cheng LC, Murugaiyah V, Chan KL. 2015. Flavonoids and phenylethanoid glycosides from Lippia nodiflora as promising antihyperuricemic agents and elucidation of their mechanism of action. J Ethnopharmacol. 176:485–493. doi:10.1016/j.jep.2015.11.025
  • Elansary HO, Salem MZM, Ashmawy NA, Yessoufou K, El-Settawy AAA. 2017. In vitro antibacterial, antifungal and antioxidant activities of Eucalyptus spp. leaf extracts related to phenolic composition. Nat Prod Res. 31:2927–2930. doi:10.1080/14786419.2017.1303698
  • Elbouzidi A, Haddou M, Baraich A, Taibi M, El Hachlafi N, Pareek A, Mesnard F, Addi M. 2025. Biochemical insights into specialized plant metabolites: Advancing cosmeceutical applications for skin benefits. J Agric Food Res. 19:101651. doi:10.1016/j.jafr.2025.101651
  • Goldsmith C, Vuong Q, Stathopoulos C, Roach P, Scarlett C. 2014. Optimization of the aqueous extraction of phenolic compounds from olive leaves. Antioxidants. 3:700–712. doi:10.3390/antiox3040700
  • Gullón P, Gullón B, Astray G, Munekata PES, Pateiro M, Lorenzo JM. 2020. Value-added compound recovery from invasive forest for biofunctional applications: Eucalyptus species as a case study. Molecules. 25:4227. doi:10.3390/molecules25184227
  • Lee JE, Jayakody JTM, Kim JI, Jeong JW, Choi KM, Kim TS, Seo C, Azimi I, Hyun JM, Ryu BM. 2024. The influence of solvent choice on the extraction of bioactive compounds from Asteraceae: A comparative review. Foods. 13(19):3151. doi: 10.3390/foods13193151.
  • Limam H, Ezzine Y, Tammar S, Ksibi N, Selmi S, Del Re G, Ksouri R, Msaada K. 2021. Phenolic composition and antioxidant activities of thirteen Eucalyptus species cultivated in North East of Tunisia. Plant Biosyst. 155:587–597. doi:10.1080/11263504.2020.1762791
  • Moges GW, Manahelohe GM, Asegie MA. 2024. Phenolic and flavonoid contents, antioxidant and antibacterial activity of selected Eucalyptus species: review. Biol Med Nat Prod Chem. 13:147–157. doi:10.14421/biomedich.2024.131.147-157
  • Nasr A, Zhou X, Liu T, Yang J, Zhu GP. 2019. Acetone-water mixture is a competent solvent to extract phenolics and antioxidants from four organs of Eucalyptus camaldulensis. Turk J Biochem. 44:231–239. doi:10.1515/tjb-2018-0438
  • Öncel I, Yurdakulol E, Keleş Y, Kurt L, Yıldız A. 2004. Role of antioxidant defense system and biochemical adaptation on stress tolerance of high mountain and steppe plants. Acta Oecol. 26:211–218. doi:10.1016/j.actao.2004.04.004
  • Park JY, Kim JY, Son YG, Kang SD, Lee SW, Kim KD, Kim JY. 2023. Characterization of chemical composition and antioxidant activity of Eucalyptus globulus leaves under different extraction conditions. Appl Sci. 13:9984. doi:10.3390/app13179984
  • Santos SAO, Vilela C, Freire CSR, Neto CP, Silvestre AJD. 2013. Ultra-high performance liquid chromatography coupled to mass spectrometry applied to the identification of valuable phenolic compounds from Eucalyptus wood. J Chromatogr B. 938:65–74. doi:10.1016/j.jchromb.2013.08.034
  • Tyagi AK, Malik A. 2011. Antimicrobial potential and chemical composition of Eucalyptus globulus oil in liquid and vapour phase against food spoilage microorganisms. Food Chem. 126:228–235. doi:10.1016/j.foodchem.2010.11.002
  • Wagay NA, Rafiq S, Khan A, Kaloo ZA, Malik AR, Pulate PV 2023. Impact of phenolics on drought stress and expression of phenylpropanoid pathway genes. In: Lone, R., Khan, S., Mohammed Al-Sadi, A. (eds) Plant Phenolics in Abiotic Stress Management. Springer, Singapore. doi:10.1007/978-981-19-6426-8_13
  • Wingfield MJ, Roux J, Slippers B, Hurley BP, Garnas J, Myburg AA, Wingfield BD. 2013. Established and new technologies reduce increasing pest and pathogen threats to Eucalypt plantations. For Ecol Manag. 301:35–42. doi:10.1016/j.foreco.2012.09.002
  • Zhu H, Song D, Zhao X. 2021. Potential applications and preliminary mechanism of action of dietary polyphenols against hyperuricemia: a review. Food Biosci. 43:101297. doi:10.1016/j.fbio.2021.101297
  • Zhou G, Xu R, Groth T, Wang Y, Yuan X, Ye H, Dou X. 2024. The combination of bioactive herbal compounds with biomaterials for regenerative medicine. Tissue Eng Part B Rev. 30:607–630. doi:10.1089/ten.teb.2024.0002

Phenolic acid and flavonoid diversity in four Eucalyptus species

Year 2025, Volume: 8 Issue: 2, 57 - 60, 29.12.2025
https://doi.org/10.46239/ejbcs.1772538

Abstract

The economic importance of Eucalyptus trees is due to their rapid growth and high biomass productivity, as well as the beneficial chemical compounds found in their various tissues. Eucalyptus cultivation is common in the southern part of Turkey, especially in the coastal areas of the Mediterranean. In this study, phenolic acids and flavonoids were analyzed in methanol extracts leaf tissues of four eucalyptus species by HPLC. Fifteen different phenolic compounds were determined in the leaf tissues of the four Eucalyptus species examined. The highest total phenolic amounts were found in E. botryoides (160.56 mg g-1DW), followed by E. tereticornis (66.47 mg g⁻¹ DW) and E. citriodora (64.02 mg g⁻¹ DW). Twelve different compounds were determined in E. botryoides and E. citriodora species, 10 in the hybrid E. camaldulensis x grandis and 9 in E. tereticornis. E. botryoides was evaluated as a natural source for catechin, E. citriodora for t-ferulic acid and rosmarinic acid, and E. tereticornis for gallic acid were evaluated as rich sources.

References

  • Albayrak FÖ, Özdeniz E, Kurt L, Keleş Y. 2021. Variation of phenolic and pigment composition depending on soil type in three serpentinovag plant species. Int J Second Metabol. 8:1–10. doi:10.21448/ijsm.765645
  • Almeida IF, Fernandes E, Lima JLFC, Valentão P, Andrade PB, Seabra RM, Costa PC, Bahia MF. 2009. Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract. J Med Food. 12:175–183.
  • Álvarez X, Cancela Á, Merchán Y, Sánchez Á. 2021. Anthocyanins, phenolic compounds, and antioxidants from extractions of six Eucalyptus species. Appl Sci. 11:9818. doi:10.3390/app11219818
  • Caponio F, Alloggio V, Gomes T. 1999. Phenolic compounds of virgin olive oil: influence of paste preparation techniques. Food Chem. 64:203–209. doi:10.1016/S0308-8146(98)00146-0
  • Chamali S, Bendaoud H, Bouajila J, Camy S, Saadaoui E, Condoret JS, Romdhane M. 2023. Optimization of accelerated solvent extraction of bioactive compounds from Eucalyptus intertexta using response surface methodology and evaluation of its phenolic composition and biological activities. J Appl Res Med Aromat Plants. 35:100464. doi:10.1016/j.jarmap.2023.100464
  • Çekiç FÖ, Özdeniz E, Öktem M, Kurt L, Keleş Y. 2018. The role of biochemical regulation on the adaptation of gypsophile and gypsovag species. Biochem Syst Ecol. 81:12–16. doi:10.1016/j.bse.2018.09.007
  • Cheng LC, Murugaiyah V, Chan KL. 2015. Flavonoids and phenylethanoid glycosides from Lippia nodiflora as promising antihyperuricemic agents and elucidation of their mechanism of action. J Ethnopharmacol. 176:485–493. doi:10.1016/j.jep.2015.11.025
  • Elansary HO, Salem MZM, Ashmawy NA, Yessoufou K, El-Settawy AAA. 2017. In vitro antibacterial, antifungal and antioxidant activities of Eucalyptus spp. leaf extracts related to phenolic composition. Nat Prod Res. 31:2927–2930. doi:10.1080/14786419.2017.1303698
  • Elbouzidi A, Haddou M, Baraich A, Taibi M, El Hachlafi N, Pareek A, Mesnard F, Addi M. 2025. Biochemical insights into specialized plant metabolites: Advancing cosmeceutical applications for skin benefits. J Agric Food Res. 19:101651. doi:10.1016/j.jafr.2025.101651
  • Goldsmith C, Vuong Q, Stathopoulos C, Roach P, Scarlett C. 2014. Optimization of the aqueous extraction of phenolic compounds from olive leaves. Antioxidants. 3:700–712. doi:10.3390/antiox3040700
  • Gullón P, Gullón B, Astray G, Munekata PES, Pateiro M, Lorenzo JM. 2020. Value-added compound recovery from invasive forest for biofunctional applications: Eucalyptus species as a case study. Molecules. 25:4227. doi:10.3390/molecules25184227
  • Lee JE, Jayakody JTM, Kim JI, Jeong JW, Choi KM, Kim TS, Seo C, Azimi I, Hyun JM, Ryu BM. 2024. The influence of solvent choice on the extraction of bioactive compounds from Asteraceae: A comparative review. Foods. 13(19):3151. doi: 10.3390/foods13193151.
  • Limam H, Ezzine Y, Tammar S, Ksibi N, Selmi S, Del Re G, Ksouri R, Msaada K. 2021. Phenolic composition and antioxidant activities of thirteen Eucalyptus species cultivated in North East of Tunisia. Plant Biosyst. 155:587–597. doi:10.1080/11263504.2020.1762791
  • Moges GW, Manahelohe GM, Asegie MA. 2024. Phenolic and flavonoid contents, antioxidant and antibacterial activity of selected Eucalyptus species: review. Biol Med Nat Prod Chem. 13:147–157. doi:10.14421/biomedich.2024.131.147-157
  • Nasr A, Zhou X, Liu T, Yang J, Zhu GP. 2019. Acetone-water mixture is a competent solvent to extract phenolics and antioxidants from four organs of Eucalyptus camaldulensis. Turk J Biochem. 44:231–239. doi:10.1515/tjb-2018-0438
  • Öncel I, Yurdakulol E, Keleş Y, Kurt L, Yıldız A. 2004. Role of antioxidant defense system and biochemical adaptation on stress tolerance of high mountain and steppe plants. Acta Oecol. 26:211–218. doi:10.1016/j.actao.2004.04.004
  • Park JY, Kim JY, Son YG, Kang SD, Lee SW, Kim KD, Kim JY. 2023. Characterization of chemical composition and antioxidant activity of Eucalyptus globulus leaves under different extraction conditions. Appl Sci. 13:9984. doi:10.3390/app13179984
  • Santos SAO, Vilela C, Freire CSR, Neto CP, Silvestre AJD. 2013. Ultra-high performance liquid chromatography coupled to mass spectrometry applied to the identification of valuable phenolic compounds from Eucalyptus wood. J Chromatogr B. 938:65–74. doi:10.1016/j.jchromb.2013.08.034
  • Tyagi AK, Malik A. 2011. Antimicrobial potential and chemical composition of Eucalyptus globulus oil in liquid and vapour phase against food spoilage microorganisms. Food Chem. 126:228–235. doi:10.1016/j.foodchem.2010.11.002
  • Wagay NA, Rafiq S, Khan A, Kaloo ZA, Malik AR, Pulate PV 2023. Impact of phenolics on drought stress and expression of phenylpropanoid pathway genes. In: Lone, R., Khan, S., Mohammed Al-Sadi, A. (eds) Plant Phenolics in Abiotic Stress Management. Springer, Singapore. doi:10.1007/978-981-19-6426-8_13
  • Wingfield MJ, Roux J, Slippers B, Hurley BP, Garnas J, Myburg AA, Wingfield BD. 2013. Established and new technologies reduce increasing pest and pathogen threats to Eucalypt plantations. For Ecol Manag. 301:35–42. doi:10.1016/j.foreco.2012.09.002
  • Zhu H, Song D, Zhao X. 2021. Potential applications and preliminary mechanism of action of dietary polyphenols against hyperuricemia: a review. Food Biosci. 43:101297. doi:10.1016/j.fbio.2021.101297
  • Zhou G, Xu R, Groth T, Wang Y, Yuan X, Ye H, Dou X. 2024. The combination of bioactive herbal compounds with biomaterials for regenerative medicine. Tissue Eng Part B Rev. 30:607–630. doi:10.1089/ten.teb.2024.0002
There are 23 citations in total.

Details

Primary Language English
Subjects Ecological Physiology
Journal Section Research Article
Authors

Fazilet Ozlem Albayrak

Fatih Aytar 0000-0002-9899-2217

Yüksel Keleş 0000-0001-8651-8385

Submission Date August 28, 2025
Acceptance Date November 8, 2025
Publication Date December 29, 2025
Published in Issue Year 2025 Volume: 8 Issue: 2

Cite

APA Albayrak, F. O., Aytar, F., & Keleş, Y. (2025). Phenolic acid and flavonoid diversity in four Eucalyptus species. Eurasian Journal of Biological and Chemical Sciences, 8(2), 57-60. https://doi.org/10.46239/ejbcs.1772538
AMA Albayrak FO, Aytar F, Keleş Y. Phenolic acid and flavonoid diversity in four Eucalyptus species. Eurasian J. Bio. Chem. Sci. December 2025;8(2):57-60. doi:10.46239/ejbcs.1772538
Chicago Albayrak, Fazilet Ozlem, Fatih Aytar, and Yüksel Keleş. “Phenolic Acid and Flavonoid Diversity in Four Eucalyptus Species”. Eurasian Journal of Biological and Chemical Sciences 8, no. 2 (December 2025): 57-60. https://doi.org/10.46239/ejbcs.1772538.
EndNote Albayrak FO, Aytar F, Keleş Y (December 1, 2025) Phenolic acid and flavonoid diversity in four Eucalyptus species. Eurasian Journal of Biological and Chemical Sciences 8 2 57–60.
IEEE F. O. Albayrak, F. Aytar, and Y. Keleş, “Phenolic acid and flavonoid diversity in four Eucalyptus species”, Eurasian J. Bio. Chem. Sci., vol. 8, no. 2, pp. 57–60, 2025, doi: 10.46239/ejbcs.1772538.
ISNAD Albayrak, Fazilet Ozlem et al. “Phenolic Acid and Flavonoid Diversity in Four Eucalyptus Species”. Eurasian Journal of Biological and Chemical Sciences 8/2 (December2025), 57-60. https://doi.org/10.46239/ejbcs.1772538.
JAMA Albayrak FO, Aytar F, Keleş Y. Phenolic acid and flavonoid diversity in four Eucalyptus species. Eurasian J. Bio. Chem. Sci. 2025;8:57–60.
MLA Albayrak, Fazilet Ozlem et al. “Phenolic Acid and Flavonoid Diversity in Four Eucalyptus Species”. Eurasian Journal of Biological and Chemical Sciences, vol. 8, no. 2, 2025, pp. 57-60, doi:10.46239/ejbcs.1772538.
Vancouver Albayrak FO, Aytar F, Keleş Y. Phenolic acid and flavonoid diversity in four Eucalyptus species. Eurasian J. Bio. Chem. Sci. 2025;8(2):57-60.