Clinical Research

The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm

Volume: 5 Number: 2 September 6, 2023
EN

The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm

Abstract

Objective: In this study, we aimed to investigate the relationship between preoperative inflammatory markers, length of hospital stay, and mortality in patients with abdominal aortic aneurysm (AAA) who underwent surgical repair. Methods: A total of 83 patients diagnosed with AAA were included in the study. A complete blood count (CBC) was performed on the first visit (pre-op 0-1 hour) in all patients. Non-ruptured cases (AAA) and ruptured cases (AAA-R) were compared. Results: 14.5% (n=12) of the patients died. Higher White blood cells and neutrophils were obtained in patients who died than in surviving patients (respectively, p=0.0002, p=0.001). Higher WBC and NALP in AAA-R patients were determined. Conclusion: WBC and Neu's values were higher in AAA patients who died post-operatively and who were detected rupture pre-operatively but PLT and HB values were similar. Normal or near-normal HB and PLT values that will be seen in the first examination of AAA cases in the emergency department may mislead clinicians or cause them to display a more optimistic attitude.

Keywords

References

  1. Michel JB, Martin-Ventura JL, Egido J, et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res. 2011;90(1):18-27.
  2. Kessler V, Klopf J, Eilenberg W, Neumayer C, Brostjan C. AAA Revisited: A Comprehensive Review of Risk Factors, Management, and Hallmarks of Pathogenesis. Biomedicines. 2022;10(1):94.
  3. Wei L, Bu X, Wang X, Liu J, Ma A, Wang T. Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017. Glob Heart. 2021;16(1):35.
  4. Svensjö S, Björck M, Gürtelschmid M, Djavani Gidlund K, Hellberg A, Wanhainen A. Low prevalence of abdominal aortic aneurysm among 65-year-old Swedish men indicates a change in the epidemiology of the disease. Circulation. 2011;124(10):1118-1123.
  5. Macaluso CR, McNamara RM. Evaluation and management of acute abdominal pain in the emergency department. Int J Gen Med. 2012;5:789-797.
  6. Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc Surg. 2018;67(1):2-77.e2
  7. Parkinson F, Ferguson S, Lewis P, Williams IM, Twine CP; South East Wales Vascular Network. Rupture rates of untreated large abdominal aortic aneurysms in patients unfit for elective repair. J Vasc Surg. 2015;61(6):1606-1612.
  8. Patel SR, Ormesher DC, Smith SR, et al. A risk-adjusted and anatomically stratified cohort comparison study of open surgery, endovascular techniques and medical management for juxtarenal aortic aneurysms-the UK COMPlex AneurySm Study (UK-COMPASS): a study protocol. BMJ Open. 2021;11(11):e054493

Details

Primary Language

English

Subjects

Emergency Medicine

Journal Section

Clinical Research

Early Pub Date

September 6, 2023

Publication Date

September 6, 2023

Submission Date

July 5, 2023

Acceptance Date

August 24, 2023

Published in Issue

Year 2023 Volume: 5 Number: 2

APA
Demirel, M. E., Kormaz, U. T. K., Çetin, Ö., Güldal, H., & Boğan, M. (2023). The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm. Eurasian Journal of Critical Care, 5(2), 56-62. https://doi.org/10.55994/ejcc.1323023
AMA
1.Demirel ME, Kormaz UTK, Çetin Ö, Güldal H, Boğan M. The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm. Eurasian j Crit Care. 2023;5(2):56-62. doi:10.55994/ejcc.1323023
Chicago
Demirel, Mustafa Enes, Ufuk Turan Kürşat Kormaz, Ömer Çetin, Hatice Güldal, and Mustafa Boğan. 2023. “The Effect of White Blood Cell and Platelet Values on Mortality in Patients With Abdominal Aortic Aneurysm”. Eurasian Journal of Critical Care 5 (2): 56-62. https://doi.org/10.55994/ejcc.1323023.
EndNote
Demirel ME, Kormaz UTK, Çetin Ö, Güldal H, Boğan M (September 1, 2023) The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm. Eurasian Journal of Critical Care 5 2 56–62.
IEEE
[1]M. E. Demirel, U. T. K. Kormaz, Ö. Çetin, H. Güldal, and M. Boğan, “The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm”, Eurasian j Crit Care, vol. 5, no. 2, pp. 56–62, Sept. 2023, doi: 10.55994/ejcc.1323023.
ISNAD
Demirel, Mustafa Enes - Kormaz, Ufuk Turan Kürşat - Çetin, Ömer - Güldal, Hatice - Boğan, Mustafa. “The Effect of White Blood Cell and Platelet Values on Mortality in Patients With Abdominal Aortic Aneurysm”. Eurasian Journal of Critical Care 5/2 (September 1, 2023): 56-62. https://doi.org/10.55994/ejcc.1323023.
JAMA
1.Demirel ME, Kormaz UTK, Çetin Ö, Güldal H, Boğan M. The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm. Eurasian j Crit Care. 2023;5:56–62.
MLA
Demirel, Mustafa Enes, et al. “The Effect of White Blood Cell and Platelet Values on Mortality in Patients With Abdominal Aortic Aneurysm”. Eurasian Journal of Critical Care, vol. 5, no. 2, Sept. 2023, pp. 56-62, doi:10.55994/ejcc.1323023.
Vancouver
1.Mustafa Enes Demirel, Ufuk Turan Kürşat Kormaz, Ömer Çetin, Hatice Güldal, Mustafa Boğan. The effect of white blood cell and platelet values on mortality in patients with abdominal aortic aneurysm. Eurasian j Crit Care. 2023 Sep. 1;5(2):56-62. doi:10.55994/ejcc.1323023

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