ROLE OF FETAL UMBILICAL AND MIDDLE CEREBRAL ARTERY DOPPLER INDICES IN DETERMINING INTRAUTERINE GROWTH RESTRICTION IN PREECLAMPTIC PREGNANCIES

Abstract

Objective:To investigatetheutility of theumbilicalartery (UA) andmiddlecerebralartery (MCA) Doppler indicesandtheirratios in determiningintrauterinegrowthrestriction (IUGR) andunfavorablebirthoutcomes in preeclampticpregnancies. MaterialandMethod:Thisprospectivestudyincluded 59 preeclampticpregnantwomenand 63 healthypregnantwomen (controls) at a gestationalweek of 31-40 whowerefollowedup at thegynecologyandobstetricsclinic of a tertiaryhospitalover a 16-month period.Aftertheevaluation of normal andpreeclampticpregnanciesusing B-Modeultrasonography, the Doppler indexvalues of the UA and MCA weredeterminedusing Doppler ultrasonography. Bydeterminingthevelocity-time wavespectraforthe UA and MCA, thesystole/diastoleratio (S/D), resistiveindex (RI), andpulsatilityindex (PI) valueswerecalculatedfollowingtheautomaticalgorithm of thedevice. Results:The UAS/D (3.47±1.29) and UA RI (0.69±0.13) values of thepreeclampticgroupstatisticallysignificantlydifferedfromthose of thecontrols (2.50 ± 0.30 and 0.59 ± 0.06, respectively) (p<0.001). The Doppler indices of theMCAwerelower in preeclampticpregnancies (PI: 1.28±0.34, RI: 0.73±0.09), andthiswasmoreprominent in fetuseswith IUGR (p<0.001). Therewerealsosignificantdifferencesbetweenthepreeclampticandhealthycontrolgroups in terms of the UA/MCA and MCA/UA Doppler indexratios (p<0.001). Conclusion:Non-invasive Doppler indicescan be used in combinationtoincreasediagnosticaccuracyandprevent fetal mortalityandmorbidity .

Keywords

• Preeclampsia
• intrauterine growth restriction
• doppler

References

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