THE EFFECT OF BLOOD PARAMETERS ON EMERGENCY DEPARTMENT FOLLOW-UP TIME AND HOSPITALIZATION STATUS IN COPD

Abstract

BACKGROUND AND AIM Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs. Neutrophils are the blood cells that respond most early to inflammation. In many studies, the Neutrophil/Lymphocyte ratio has been shown to be an important component of the inflammatory response. RDW is a routine component of the hemogram, which shows heterogeneity in erythrocyte size and is used as a laboratory value for anemia. Research has shown that high RDW can be used as an indicator of poor prognosis in COPD. We aimed to show the effect of NLR and RDW values on morbidity by examining the correlation with length of hospital stay in COPD patients. MATERIALS AND METHODS Complete blood count data and length of hospital stay of COPD patients who were admitted to the emergency department of our hospital with symptoms of COPD exacerbation in the last six months were investigated retrospectively. The relationship between RDW values in complete blood count and neutrophil/lymphocyte ratios (NLR) in the emergency department and inpatient admission rates was examined. RESULTS A total of 101 patients, 69.3% of whom were male, were diagnosed with COPD and admitted to the emergency department with acute respiratory failure were included in the study. As a result of the statistical study, there is a significant difference in RDW-SW and NLR values according to the length of stay in the emergency department. CONCLUSION In our study, we observed that patients with higher RDW and NLR values had longer hospital stays. This has shown that RDW and NLR measurements may be important in determining the morbidity of the disease.

Keywords

• COPD
• COPD exacerbation (AECOPD)
• NLR
• RDW
• Length of hospital stay (LOS).

KOAH’TA KAN PARAMETRELERİNİN ACİL SERVİS TAKİP SÜRESİ VE YATIŞ DURUMUNA ETKİSİ

Abstract

GİRİŞ ve AMAÇ Kronik obstrüktif akciğer hastalığı (KOAH), hava akışını azalması ile karakterize, akciğer dokusunda hasara neden olan solunum yollarının ve akciğerlerin kronik enflamatuar bir hastalığıdır. Nötrofiller, inflamasyona en erken yanıt veren kan hücreleridir. Birçok çalışmada Nötrofil/Lenfosit oranının inflamatuar yanıtın önemli bir bileşeni olduğu gösterilmiştir. RDW, eritrosit boyutunda heterojenlik gösteren ve anemi için bir laboratuvar değeri olarak kullanılan hemogramın rutin bir bileşenidir. Araştırmalar, yüksek RDW'nin KOAH'da kötü prognozun bir göstergesi olarak kullanılabileceğini göstermiştir. Biz de NLR ve RDW değerlerinin KOAH hastalarında hastanede kalış süresiyle korellasyonunu inceleyerek morbidite üzerindeki etkisini göstermeyi amaçladık. MATERYAL VE METOD Son altı ayda hastanemiz acil servisine KOAH alevlenme semptomlarıyla başvuran KOAH hastalarının tam kan sayımı verileri ve hastanede kalış süreleri retrospektif olarak araştırılmıştır. Tam kan sayımında yer alan RDW değerleri ile Nötrofil/Lenfosit oranlarının (NLR) acil serviste kalış süreleri ve yataklı servislere yatırılma oranları arasındaki ilişki incelenmiştir. BULGULAR Çalışmaya toplamda KOAH tanısı olan ve acil servise akut solunum yetmezliği ile başvuran, %69,3’ü erkeklerden oluşan 101 hasta dahil edilmiştir. Yapılan istatistiksel çalışma sonucunda RDW-SW ve NLR değerleri acil serviste kalış süresine göre anlamlı farklılık görülmektedir. Ayrıca RDW ve NLR değerlerinin birbiriyle korelasyonu hesaplandığında da sonuçlar istatistiksel olarak anlamlı bulunmuştur. SONUÇ Çalışmamızda RDW ve NLR değeri daha yüksek olan hastaların hastanede kalış sürelerinin daha uzun olduğunu gözlemledik. Bu durum hastalığın morbiditesini belirlemede RDW ve NLR ölçümlerinin önemli olabileceğini göstermiştir.

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