A Rare Heart Valve Involvement in Adult Polycystic Kidney Disease: A Case Report

Abstract

A Rare Heart Valve Involvement in Adult Polycystic Kidney Disease: A Case Report

Abstract

In adult polycystic kidney patients, heart involvement is frequently observed in the progressing process of the disease, as well as the pathologies created in various other organs. Among others, left ventricular hypertrophy and mitral valve prolapse are generally observed. A 42-year-old female patient, receiving dialysis due to chronic renal failure resulting from autosomal dominant polycystic kidney disease, was admitted to the cardiology outpatient clinic with complaints of high blood pressure, dyspnea and abdominal pain. During clinical examinations, a cyst was detected in the tricuspid valve on echocardiography. In this case study, we aimed to present a patient with a cyst on the tricuspid valve, which has not been previously encountered in adult polycystic kidney patients.

Keywords

• adult polycystic kidney disease
• tricuspid valve
• giant hepatic cyst
• heart failure
• dyspnea
• left ventricular hypertrophy

References

1. 1. Bergmann C, Guay-Woodford LM, Harris PC, Horie S, Peters DJM, Torres VE. Polycystic kidney disease. Nat Rev Dis Primers. 2018;4(1):50. Published 2018 Dec 6. doi:10.1038/s41572-018-0047-y
2. 2. Torres VE, Harris PC, Pirson Y. Autosomal dominant polycystic kidney disease. Lancet. 2007;369(9569):1287-1301. doi:10.1016/S0140-6736(07)60601-1
3. 3. Granot Y, Van Putten V, Przekwas J, Gabow PA, Schrier RW. Intra- and extracellular proteins in human normal and polycystic kidney epithelial cells. Kidney Int. 1990;37(5):1301-1309. doi:10.1038/ki.1990.115
4. 4. Helal I, Reed B, Mettler P, et al. Prevalence of cardiovascular events in patients with autosomal dominant polycystic kidney disease. Am J Nephrol. 2012;36(4):362-370. doi:10.1159/000343281
5. 5. Ecder T, Schrier RW. Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease. Nat Rev Nephrol. 2009;5(4):221-228. doi:10.1038/nrneph.2009.13
6. 6. Belz MM, Fick-Brosnahan GM, Hughes RL, et al. Recurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease. Kidney Int. 2003;63(5):1824-1830. doi:10.1046/j.1523-1755.2003.00918.x
7. 7. Lumiaho A, Ikäheimo R, Miettinen R, et al. Mitral valve prolapse and mitral regurgitation are common in patients with polycystic kidney disease type 1. Am J Kidney Dis. 2001;38(6):1208-1216. doi:10.1053/ajkd.2001.29216
8. 8. Chebib FT, Hogan MC, El-Zoghby ZM, et al. Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies. Kidney Int Rep. 2017;2(5):913-923. Published 2017 Jun 6. doi:10.1016/j.ekir.2017.05.014

9. 9. Leier CV, Baker PB, Kilman JW, Wooley CF. Cardiovascular abnormalities associated with adult polycystic kidney disease. Ann Intern Med. 1984;100(5):683-688. doi:10.7326/0003-4819-100-5-683