Hereditary Angioedema and Allergic Reaction Due to Fresh Frozen Plasma

Year 2019, Volume: 1 Issue: 1, 39 - 40, 23.04.2019

Şükrü Gürbüz , Muhammed Ekmekyapar

Abstract

Hereditary angioedema (HA) is a rare disorder
characterized by recurrent angioedema attacks and autosomal dominant
transmission. Plasma C1 occurs due to esterase inhibitor deficiency. Angioedema
is most commonly seen in the extremities, oropharynx, and visceral organs.
Intestinal mucosal edema can cause temporary obstruction and severe abdominal
pain that can interfere with acute abdomen. It should be kept in mind that
antihistamines, stereoids, androgens, FFP (Fresh frozen plasma) and C1 esterase
inhibitors used in the treatment of these patients may also develop allergies
and these drugs should be used with caution. 
We aimed to present a 51 years old female patient (Figure-1) with a
diagnosis of hereditary angioedema in our case which developed FFP (Fresh
frozen plasma) allergy.

Keywords

Hereditary angioedema, FFP (Fresh frozen plasma), allergy

References

• 1-Huang YT, Lin YZ, Wu HL et al: Hereditary angioedema: a family study. Asian Pac J Allergy Immunol 2005;23:227-33.
• 2-Isselbacher KJ. Harrison’s principles of internal medicine, 15th ed. McGraw-Hill, 2001
• 3- Osler W. Hereditary angio-neurotic oedema. Am J Med Sci 1888;95:362-7.
• 4- Frank MM. Hereditary angioedema: a half century of prog¬ress. J Allergy Clin Immunol 2004;114:626-8.
• 5-Witschi A, Krahenbühl L, Frei E, Saltzman J, Spath PJ, Müller UR. Colorectal intussusception: An unusual gastroin¬testinal complication of hereditary angioedema. Int Arch Allergy Immunol 1996;111:96-8.
• 6- Frank MM. Herditary angioedema: a half century of progress. J Allergy Clin Immunol 2004;114:626-8.