Vasculitic Neuropathy in a Thırd Trimester Pregnant Patient with Systemic Lupus Erythematosus

Abstract

Sistemik lupus eritematosus (SLE) daha çok doğurganlık çağındaki kadınlarda görülen inflamatuar otoimmun bir hastalıktır. 20 yaşındaki 35 haftalık gebe olan bayan hasta kliniğimize 20 gündür olan bacak ağrısı, bacaklarda kuvvetsizlik ve sol düşük ayak şikayetleri ile başvurdu. Özgeçmişinde ayda bir defa olan oral ülserler, zaman zaman eklem ağrıları ve gün ışığında belirginleşen malar rash vardı. yapılan EMG de duyusal ağırlıklı sensorimotor polinöropati tespit edildi ve hastaya SLE' ye bağlı vaskülitik nöropati tanısı konuldu. silik semptom ve bulguları olan SLE hastaları gebelik dönemindeki hastalığın sistemik alevlenmeleri neticisinde kötüleşebilir, dahası bu durum fetal ve maternal mortalitenin artmasına da neden olabilir. Dolayısıyla klinisyenler SLE li hastalarının gebelik dönemindeki alevlenmelere bağlı gelişebiliecek muhtemel komplikasyonlara karşı uyanık olmalılardır

Keywords

• Sistemik lupus eritematosus, gebelik, periferal nöropati

Vasculitic Neuropathy in a Thırd Trimester Pregnant Patient with Systemic Lupus Erythematosus

Abstract

Systemic lupus erythematosus (SLE) is an inflammatory, autoimmune disease that predominantly occurs in women of childbearing age. A 20-year-old, 35 week pregnant patient was admitted to our clinic with a 20 day history of leg pain, numbness in the feet, and left foot drop. On further examination, the patient reported oral ulcers once a month, occasional joint swelling, increasing malar rash under sunlight. Sensory-predominant sensorimotor polyneuropathy was detected on EMG, and a diagnosis of vasculitic neuropathy-related SLE was made. SLE patients with vague signs and symptoms may have new neurologic signs during pregnancy due to relapse of systemic disease. Moreover, there can be an increase in both fetal and maternal mortality. Therefore, clinicians should be wary of possible aforementioned complications during prenatal examinations of their pregnant patients with SLE.

Keywords

• Systemic lupus erythematosus, pregnancy, peripheral neuropathy

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