From Rickets Prevention to Vitamin D Intoxication

Year 2014, , - , 01.09.2014

Momcilo Pavlovic Karolina Berenji

https://doi.org/10.15197/sabad.1.11.71

Abstract

Hypervitaminosis D occurs in infants due to increased intake of vitamin D and results in hypercalcemia and hypercalciuria. We present the case of a 4.5-month old infant with signs of vitamin D intoxication, which occurred due to supplementation for the purpose of rickets prevention and diet with vitamin D-fortified milk. The clinical manifestations were constipation, vomiting and failure to thrive. After excluding hormonal, tumoral and malformative (Williams syndrome) causes, treatment included hyperhydration, loop diuretics and prednisone. This case highlights the need for proper informing of parents on the manners of vitamin D supplementation during the first year of life in order to avoid dangers of parental dosing errors.

Keywords

Vitamin D intoxication, hypercalcemia, Williams syndrome, prednisone

From Rickets Prevention to Vitamin D Intoxication

Abstract

İnfantlarda D vitamin fazlalığı artmış vitamin D alımı neticesinde olur ve hiperkalsemi ve hiperkalsiüri ile sonuçlanır. Biz, vitamin D intoksikasyonu bulguları olan 4.5 aylık bir infant vakası sunuyoruz. Bu vakada vitamin D fazlalığı, riketsden korumak amacıyla diyette vitamin D ile takviye edilmiş süt kullanılması ile oluşmuştu. Klinik belirtiler kabızlık, kusma ve gelişme geriliğiydi. Hormonal, tümöral ve malformatif (Williams syndrome) sebepler dışlandıktan sonra,hiperhidrasyon, loop diüretikleri ve prednison ile tedavi edildi. Sunulan vaka, parenteral doz hatalarının tehlikelerini önlemek için yaşamın ilk yılında vitamin D suplementasyon metodları hakkında ebeveynlerin bilgilendirilmesinin ne kadar önemli olduğunu göstermektedir

Keywords

Vitamin D zehirlenmesi, hiperkalsemi, Williams sendromu, prednizon

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