Smoking and Lipid Profile in Pilonidal Sinus Patients

Abstract

The purpose of our study was to determine the risk factors such as lipid profile and smoking on the pathogenesis of sacrococcygeal pilonidal sinus disease (SPD). A total of 26 with SPD and 42 control patients were enrolled for this study. We retrieved data of patients comprising patient age, gender, body mass index (BMI), smoking and lipid profile. Total cholesterol (TC), triglycerides (TG), low density lipoprotein- cholesterol (LDL-C) and high density lipoprotein- cholesterol (HDL-C) were evaluated for lipid profile. Mean age and BMI of SPD and control group were 21.7±1.3 and 34.5±5.7 years (p

Keywords

• Smoking, lipid profile, sinus pilonidalis

Smoking and Lipid Profile in Pilonidal Sinus Patients

Öz

Çalışmamızda pilonidal sinus hastalığında (PSH) risk faktörü olarak sigara kullanımı ve lipid profilinin patogenezdeki rolünü araştırmayı amaçladık. Çalışmamıza PSH olan 26 ve 42 kontrol olmak üzere toplam 68 olgu alınmıştır. Tüm olguların vücut kitle indeksleri (VKİ), kan lipit seviyeleri ve sigara kullanımları araştırıldı. PSH grubu ve kontrol grubunun sırasıyla yaş ortalaması 21,7±1,3 yıl, 34,5±5,7 yıl (p<0.001), VKİ ortalaması 25,7±1,5 kg/m2, 26,0±2,5 kg/m2 (p=0,6) idi. PSH ve kontrol gruplarında sırasıyla Total-kolesterol (TK) 163,8±29,0 mg/dl, 193,6±31,0 mg/dl (p<0.001), Düşük dansiteli lipoprotein-Kolesterol (DDL-K) 103,6±28,7 mg/dl, 128,5±27,5 mg/dl (p<0.001) ve Yüksek dansiteli lipoprotein-Kolesterol (YDL-K) 41,0±9,0 mg/dl, 48,0±10,5 mg/dl p=0.006) olup, değerler arasında anlamlı fark vardı, fakat ve Trigliserid (TG) 94,3±47,9 mg/dl, 83,9±46,3 mg/dl olup, değerler arasında fark saptamadık (p=0.3). Sigara kullanımı PSH olan grupta 22/26 (%84,6), kontrol grubunda 16/42 (%38,1) olguda saptandı (p<0.001). PSH olan olgularda TK, DDL-K ve YDL-K değerlerini daha düşük, fakat sigara kullanımının daha fazla olduğunu saptadık. Pilonidal sinüs grubunda sigara kullanımının artmış olması YDL-K değerinin düşüklüğü için bir etkendir, fakat PSH olan olgularda total kolesterol değerini düşüren bir etken olup olmadığını belirlemek için daha fazla olgunun katıldığı çalışmalara ihtiyaç vardır

Anahtar Kelimeler

• Sigara, lipid profili, pilonidal sinüs

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