Angiomyofibroblastoma of The Vulva

Öz

Anjiyomiyofibroblastom, genellikle orta yaş kadınlarda,pelviperianal bölgede ender olarak görülen,çok iyi sınırlı selim bir tümördür.Tümör hücreleri damarlar etrafında iğsi daireler şeklinde yerleşmişlerdir.Hemen her zaman desmin ve vimentin,sürekli olarak östrojen ve progesteron reseptörleri için olmakla birlikte bazen de CD 34 için immünreaktiftirler.Cerrahi tedavide tam ekzisyon gereklidir.Yetersiz tedaviden kaçınmak için,tümörü agresif anjiyomiksomdan ayırt etmek oldukça önemlidir.Burada,46 yaşında postmenopozal dönemdeki bir kadın hastada,farklı histopatolojik bulguları olan bir vulvar anjiyomiyofibroblastom olgusu sunulmaktadır.Tümör hücreleri fibrodipoz doku içermekte ve desmin ve aktin için negatif immünreaktivite göstermektedir

Anahtar Kelimeler

• Anjiyomiyofibroblastom, vulva, postmenopoz

Angiomyofibroblastoma of The Vulva

Abstract

Angiomyofibroblastoma is a rare,benign,well-circumscribed neoplasm predominantly occurring in the pelviperineal region of middle-aged women. The tumour cells are round-to-spindle shaped concentrated around vessels. They almost have immunoreactivity for desmin and vimentin,consistently positive for estrogen and progesteron receptors,occasionally positive for CD 34. The complete surgical excision of the tumour is necessary. It is important to distinguish this tumour from especially aggressive angiomyxoma to avoid inadequate treatment. Here,we report a case of vulvar angiomyofibroblastoma in a 46-year old postmenopausal woman whose findings were differentiating from others. Histologically,the tumour involved fibroadipose tissue and immunoreactivity for desmin and actin was negative.

Keywords

• Angiomyofibroblastoma, vulva, postmenopause

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