Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma

Abstract

The association between pancreas adenocarcinoma and breast infitrative ductal carcinoma is extremly rare. A 55-year-old woman was diagnosed as having a pancreatic adenocarcinoma. The patient underwent a Whipple operation. At the pathology consultation; result was well- differentiated adenocarcinoma, Six months later, patient came to routine polyclinic control with breast mass. After the true-cut biopsy, invasive ductal breast carcinoma was detected in pathological examination. The prosedure was breast conservation surgery and axillary lymph node dissection. We administered adjuvan chemotherapy and radiotherapy. We think that common genetic mechanism between pancreatic adenocarcinoma and breast infiltrative ductal carcinoma might be present. Clinicians should pay attention to the possibility associated breast cancer in preoperative screeening and follow up of patients with pancreatic adenocarcinoma.

Keywords

• Pancreas, breast, cancer, synchronous

Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma

Öz

Pankreas adenokanseri ile memenin infiltratif duktal karinomu birlikteliği oldukça nadirdir. Ellibeş yaşında bir bayan hastaya pankeras adenokanseri tanısı ile Whipple operasyonu uygulandı. Histopatolojik inceleme sonucu iyi diferansiye adenokanser olarak rapor edildi. Altı ay sonra rutin poliklinik kontrolleri sırasında meme de kitle tespit edildi. Alınan trucut iğne biyopsisinde invaziv duktal meme kanseri saptandı. Hastaya meme koruyucu cerrahi ve aksiler lenf nodu diseksiyonu uygulandı. Operasyon sonrası adjuvan kemoterapi ve radyoterapi uygulandı. Pankreas adenokanseri ile memenin invaziv duktal karsinomu arasında genetik bir benzerlik olabileceğini düşünmekteyiz. Bu nedenle pankeras kanseri olan hastalarda meme kanseri görülebileceği ihtimali ile klinisyenler daha dikkatli olmaları gerekmektedir

Anahtar Kelimeler

• Pankreas, meme, kanser, eş zamanlı

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