The Assessment as Bone Mineral Density of Bone Damage in Radiology Workers Occupationally Exposed to Ionizing Radiation

Abstract

We examined the effects of occupational ionizing radiation exposure in radiology workers on bone mineral density and serum alkaline phosphates (ALP) levels. 49 subjects, aged between 21-48 years (33.86 years), working in the department of radiology were enrolled to this study. 26 subjects were female and 23 were male. Control group consisted of 40 healthy subjects aged between 22-49 years (mean 33.83) who had never been exposed to radiation; 21 of these were female and 19 male. Venous blood samples were obtained from the radiology workers and control group and serum alkaline phosphatase levels analysis of samples were performed. The bone mineral density (BMD) was assessed in the spine and the hip with a dual-energy x-ray absorptiometry (DEXA) instrument. T-scores of radiology workers was lower than control group significantly (P < 0.01). Serum ALP levels of radiology workers was lower than control group significantly (P < 0.01). T-scores and serum ALP levels of private sector workers were lower than state hospital workers but there was no significantly difference among them (P > 0.05). T-scores of the men at the control group were higher than the women\'s however the case was just the opposite for the work group. In radiology workers exposed to long-term low-dose ionizing radiation has negative effect on bone mineral density and serum ALP levels.

Keywords

• Radiation, bone mineral density, serum ALP

The Assessment as Bone Mineral Density of Bone Damage in Radiology Workers Occupationally Exposed to Ionizing Radiation

Öz

Biz radyoloji çalışanlarında mesleki iyonize radyasyon maruziyetinin kemik mineral yoğunluğu ve serum alkalin fosfotaz (ALP) seviyeleri üzerine etkilerini inceledik. Radyoloji departmanında çalışan, yaşları 21-48 (33.86) arasında değişen 26’sı kadın ve 23’ü erkek toplam 49 radyoloji çalışanı bu çalışma kapsamına alındı. Kontrol grubu, herhangi bir şekilde radyasyona maruz kalmamış sağlıklı, yaşları 22-49 (33.83) arasında değişen 21’i kadın ve 19’u erkek 40 kişiden oluşturuldu. Radyoloji çalışanı ve kontrol grubundaki kişilerin her birinden alınan venöz kan örneklerinden serum alkalin fosfotaz analizleri yapıldı. Omur ve kalça BMD’leri dual enerji x-ray absorptiometry (DEXA) cihazıyla ölçüldü. Radyoloji çalışanlarının T-skorları ve Serum ALP seviyeleri kontrol gruplarından anlamlı olarak düşük bulundu (p<0.01). Özel sektör çalışanlarının T-skorları ve serum ALP seviyeleri devlet hastanesi çalışanlarından düşük bulundu fakat aralarındaki fark anlamlı değildi (P > 0.05). Erkeklerin T-skorları kontrol gruplarında kadınlardan yüksek olmasına rağmen çalışma grubunda bu durumun tam tersi bulundu. Radyoloji çalışanlarında uzun dönem düşük doz iyonize radyasyon maruziyeti kemik mineral yoğunluğu ve serum ALP seviyeleri üzerinde olumsuz etkilidir

Anahtar Kelimeler

• İyonize radyasyon, kemik mineral yoğunluğu, serum ALP

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