Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India

Abstract

Onychomycosis is a major public health problem with high incidence, associated morbidity and long lasting treatment with anti-fungal agents. This study was carried out to know the clinico-mycological pattern of onychomycosis which can help in the control of this infection. The aim of this study was to determine the prevalence of various causative agents of onychomycosis, to identify the clinical pattern and to analyze the risk factors. This was a prospective study carried over a period of one year from Ist February 2010 to 31st january 2011 on samples from 150 patients with clinically suspected nail infections attending the dermatology department of SKIMS Medical college, Kashmir. The nails were evaluated clinically and the nail samples were subjected to direct microscopy and culture. 66.6% samples were positive by direct microscopy and culture. Males were infected more than females. The commonest age group infected was 21-30 years. Finger nails were affected more frequently than toe nails and distolateral subungal onychomycosis was the most common clinical type seen in 66% patients. The etiological agents were dermatophytes (62.68%), NDM (29.85%), yeasts (7.46%). Among dermatophytes T. rubrum was the commonest etiological agent.

Keywords

• Nail, candida, onychomycosis, yeast,dermatophyte, agar

Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India

Abstract

Onikomikozler yüksek insidans ile birlikte morbidite ve anti-fungal ajanlar ile uzun süren tedavi gerektiren önemli bir halk sağlığı problemidir. Bu çalışma enfeksiyon kontrolünde yardımcı olabilecek onikomikoza ait kliniko-mikolojik özellikleri tespit etmek amacıyla planlandı. Bu çalışmanın amacı, risk faktörlerini analiz etmek ve klinik özellikleri tespit edebilmek için, onikomikozun değişik etken ajanlarının prevelansını belirlemekti. Bu çalışma 1 Şubat 2011-31 Ocak 2012 tarihleri arasında 1 yıllık periyotta SKIMS Kaşmir Tıp Fakültesi dermatoloji bölümüne başvuran klinik olarak tırnak enfeksiyonu şüphesi olan 150 hastadan alınan örnekler üzerinde yapılan prospektif bir çalışmadır. Tırnaklar klinik olarak değerlendirildi ve tırnak örnekleri direkt mikroskopi ve kültür yapılarak ile incelendi. Örneklerde %66.6’sı direkt mikroskopi ve kültürde pozitif idi. Erkekler bayanlardan daha fazla enfekte idi. En sık enfekte yaş grubu 21-30 yaş arası idi. El tırnakları ayak tırnaklarından daha fazla enfekte idi ve %66 hastada görülen distolateral subungal onikomikoz en sık klinik tip idi. Etiyolojik ajanlar dermatofit (%52.68), NDM (%29.85) ve yeast (%7.46) idi. Dermatofitler arasında T. Rubrum en sık etiyolojik ajan idi

Keywords

• Tırnak, kandida, onikomikoz, dermatofit, agar

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