Adverse Cardiac Effects Of Decongestants Agents

Abstract

Especially in spring and winter months many people use excessive dose topical or systemic decongestant agents to relief the allergic or infectious nasal congestive symptoms without physicians\' prescription. Although these agents bring some symptomatic benefits, sometimes serious adverse cardiac events reported at all drug users, especially who had known cardiac disease. These agents may cause slightly elevation of blood pressure in hypertensive patients, can trigger mortal arrhythmias like ventricular tachycardia, can also trigger myocardial infarction patients with known coronary artery disease or normal coronary artery and may cause decompensation of heart failure. In conclusion all these decongestant agents give only symptomatic relief and they don\'t treat flu and allergic disease. For this reason if the symptoms are mild or moderate not using these agents will be more wisely.

Keywords

• Decongestants, pseudoephedrine, phenylephrine, cardiac, arrhythmias

Adverse Cardiac Effects Of Decongestants Agents

Abstract

ellikle bahar ve kış aylarında insanların birçoğu allerjik ya da enfeksiyona bağlı nasal konjesyonu gidermek için gereğinden fazla ve sıklıkla reçetesiz topikal veya sistemik dekonjestanları kullanmaktadırlar. Bu ilaçların semptomatik faydalarına karşın özellikle bilinen kardiyak hastalığı olanlar başta olmak üzere tüm kullanan kişilerde ciddi istenmeyen kardiyak olaylara neden olabildiği bildirilmiştir. Hipertansif hastalarda az da olsa kan basıncını yükselttiği, bazıları ventriküler taşikardi gibi ölümcül olabilen pek çok aritmiyi tetiklediği, bilinen koroner arter hastalığı olan ya da normal koroner anatomiye sahip kişilerde miyokard enfarktüsünü tetikleyebildiği, kalp yetmezliği olan hastalarda dekompansasyona neden olabildiği rapor edilmiştir. Sonuç olarak tüm dekonjestan ajanların allerjiyi, soğuk algınlığını tedavi etmediği sadece semptomatik rahatlama sağladığı unutulmamalıdır. Bu nedenle semptomlar hafif veya orta derecede ise öncelikle ilaç dışı yöntemlerin denenmesi mevcut yan etkiler düşünüldüğünde daha akıllıcadır

Keywords

• Dekonjestanlar, psödoefedrin, fenilefrin, kardiyak, aritmi

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