THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD

Volume: 5 Number: 1 March 1, 2008
  • Than Copd
TR EN

THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD

Abstract

Aim: Nowadays, there are still some difficulty to distinguish smoker asthmatic patients and COPD. Differentiation of these disorders is very important as their treatment choices are different. The aim of this study is to investigate the presence of auscultation together with pulmonary function test (PFT) findings and the power of these findings in distinguishing asthma and COPD patients. Methods: 585 patients diagnosed of asthma and COPD according to international guidelines in our out-patient clinic were reviewed and their semptoms, risk factors, physical exam findings and PFTs were evaluated. Results: The study consisted of 294 women and 291 men. The mean age of patients was 41.2±14.5 years. 433 patients were asthmatic and 152 had COPD. While there was a significantly concordance between auscultation and PFTs in non-smoker patients with asthma (p=0.00), we didn’t find any accordance in smoker patients with asthma and COPD (p>0.05), If auscultation was normal and only FEF25-75 parameter showing obstruction in PFT was lower this condition was found more specific for asthma (without cigarette influence) than COPD (p=0.000). Conclusion: Our data shows that abnormal findings of auscultation and PFTs were more concordance in non-smoker patients with asthma. This indicates that PFTs may be utilized noninvasively to distinguish asthma and COPD cases in outpatient clinics

Keywords

References

  1. Global strategy for asthma management and prevention: update report 2006. NIH Publication No. 02–3659. Available at: www.ginasthma.com.
  2. NHLBI/WHO global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;163,1256-1276
  3. Bergeron C, Boulet LP. Structural changes in airway diseases: characteristics, mechanisms, consequences, modulation. Chest 2006;129(4):1068-87
  4. Buist AS. Similarities and differences between asthma and chronic obstructive pulmonary disease: treatment and early outcomes. Eur Respir J Suppl 2003;39:30s-35s
  5. Bousquet J, Jeffery PK, Busse WW, Johnson M, Vignola AM. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 2000;161:1720–45
  6. Hamid Q, Song YL, Kotsimbos TC, et al. Inflammation of small airways in asthma. J Allergy Clin Immunol 1997;100:44–51.
  7. Martin RJ. Small airway and alveolar tissue changes in nocturnal asthma. Am J Respir Crit Care Med 1998;157:5188–190
  8. Laitinen LA, Laitinen A, Altraja A, et al. Bronchial biopsy findings in intermittent or “early” asthma. J Allergy Clin Immunol 1996;98:53–6

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Than Copd This is me
Acıbadem Health Group, Departments of Allergy and Chest Diseases, İstanbul, Turkey

Publication Date

March 1, 2008

Submission Date

April 27, 2015

Acceptance Date

-

Published in Issue

Year 2008 Volume: 5 Number: 1

APA
Copd, T. (2008). THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD. European Journal of General Medicine, 5(1), 16-20. https://izlik.org/JA45PJ46WX
AMA
1.Copd T. THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD. European Journal of General Medicine. 2008;5(1):16-20. https://izlik.org/JA45PJ46WX
Chicago
Copd, Than. 2008. “THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD”. European Journal of General Medicine 5 (1): 16-20. https://izlik.org/JA45PJ46WX.
EndNote
Copd T (March 1, 2008) THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD. European Journal of General Medicine 5 1 16–20.
IEEE
[1]T. Copd, “THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD”, European Journal of General Medicine, vol. 5, no. 1, pp. 16–20, Mar. 2008, [Online]. Available: https://izlik.org/JA45PJ46WX
ISNAD
Copd, Than. “THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD”. European Journal of General Medicine 5/1 (March 1, 2008): 16-20. https://izlik.org/JA45PJ46WX.
JAMA
1.Copd T. THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD. European Journal of General Medicine. 2008;5:16–20.
MLA
Copd, Than. “THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD”. European Journal of General Medicine, vol. 5, no. 1, Mar. 2008, pp. 16-20, https://izlik.org/JA45PJ46WX.
Vancouver
1.Than Copd. THE DECREASE OF FEF25-75 IS MORE SPECIFIC FOR ASTHMA THAN COPD. European Journal of General Medicine [Internet]. 2008 Mar. 1;5(1):16-20. Available from: https://izlik.org/JA45PJ46WX