HISTOLOGICAL INVESTIGATION OF TESTICULAR AND ACCESSORY SEX GLANDS IN RAM LAMBS IMMUNIZED AGAINST RECOMBINANT GNRH FUSION PROTEINS

Abstract

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HISTOLOGICAL INVESTIGATION OF TESTICULAR AND ACCESSORY SEX GLANDS IN RAM LAMBS IMMUNIZED AGAINST RECOMBINANT GNRH FUSION PROTEINS

Abstract

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Keywords

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References

1. D’occhio MJ, Fordyce G, Whyte TR, Aspden WJ, Trigg RE. Reproductive responses of cattle to GnRH agonists. Anim reprod Sci 2000; 60-61:433-42
2. Reeves JJ, Chang CF, De Avila DM, Grieger HE, Johnson HE, Roberts AJ. Vaccine against endogenous hormones: A possible future tool in animal production. J Dairy Sci 1989;72: 3363-71
3. Bonneau M, Enright WJ. Immunocastration in cattle and pig. Livestock Prod Sci 1995;42: 193-200
4. Talwar GP, Singh OM, Pal Rahul, Chatterjee N. Vaccines for control of fertility and hormone dependent cancers. Int J Immunopharmac 1992;14:511-4
5. Zhang Y, Rozell TG, De Avila DM, Bertrand KP, Reeves JJ. Development of recombinant ovalbumin-luteinizing hormone releasing hormone as a potential sterilization vaccine. Vaccine 1999;17:2185-91
6. Quesnell MM, Zhang Y, De Avila DM, Bertrand KP, Reeves JJ. Immunization of male mice with Luteinizing Hormone-Releasing Hormone fusion protein reduces testicular and accesory sex gland function. Biol Reprod 2000;63:347-53
7. Sosa JM, Zhang Y, DeAvila, DM, Bertrand KP, Reeves JJ. Technical note: Recombinant LHRH fusion protein suppresses estrus in heifers. J Anim Sci 2000;78:1310-2
8. Stevensen V. Vaccine delivery systems: Potential methods for use in antifertility vaccines. Am J Reprod Immunol 1993; 29: 176-88

9. Ulker H, Kanter M, Gokdal O, De Avila DM, Reeves JJ. The effects of recombinant LHRH fusion proteins on testicular development and histology in ram lambs. Dtsch Tierärztl Wschr 2001;108:459-64
10. Ulker H, Kanter M, Gokdal O, et al. Testicular development, histological appearance of the testis in ram lambs immunized against recombinant LHRH fusion proteins. Anim Reprod Sci 2005;86: 205-19 and
11. Ferro VA, O’Grady JE, Notman J, Stimson WH. Immunological castration using a gonadotrphin-releasing hormone analogue conjugated to PPD. Food Agric Immunol 1995;7:259-72
12. Ferro VA, Stimson WH. Effects of adjuvant, dose and carrier pre-sensitisation on the immunisation efficacy of a GnRH analogue. Drug Des Discovery 1996;14:501-8
13. Dowsett KF, Tshewang U, Knott LM, Jackson AE, Trigg TE. Immunocastration of colts and immunospeying of fillies. Immunol Cell Biol 1993;5:501-8
14. Brown BW. Division of animal production. Csiro, Blactown, NSW, Australia, 1994;15-21
15. Zeng XY, Turkstra JA, Wiel van de DFM. Active Immunization against Gonadotrophin- releasing Hormone in Chinese Male Pigs. Reprod Dom Anim 2001;36:101-5
16. Ferro VA, Khan MAH, Latimer VS, Brown D, Urbanski HF, Stimson WH. Immunoneutralisation of GnRH-I, without cross-reactivity to GnRH-II, in the development of a highly specific anti-fertility vaccine for clinical and veterinary use. J Reprod Immunol 2001;51:109-29
17. Awoniyi CA, Chandrashekar V, Arthur RD, Schanbacher BD, Falvo RE. Changes in testicular morphology in boars actively immunized against gonadotropin hormone- releasing hormone. J Androl 1988;9:160–71
18. Awoniyi CA, Reece MS, Hurst BS, Faber KA, Chandrashekar V, Schlaff WD. Maintenance of sexual function with testosterone in the gonadotropin-releasing hormone-immunized hypogonadotropic infertile male rat. Biol Reprod 1993;49:1170–7
19. Kiyma Z, Adams TE, Hess BW, Riley ML, Murdoch WJ, Moss GE. Gonadal function, sexual behavior, feedlot performance, and carcass traits of ram lambs actively immunized against GnRH. J Anim Sci 2000;78(9):2237-43
20. Giri DK, Jayaraman S, Neelaram GS, Jayashankar R, Talwar GP. Prostatic hypoplasia in bonnet monkeys following active immunization with semisynthetic anti- LHRH Vaccine. Exp Mol Pathol 1991;54:255-64