THE OXIDANT EFFECTS OF HYPERBARIC OXYGENATION AND AIR POLLUTION IN ERYTHROCYTE MEMBRANES (HYPERBARIC OXYGENATION IN AIR POLLUTION)

Abstract

-

Keywords

• -

THE OXIDANT EFFECTS OF HYPERBARIC OXYGENATION AND AIR POLLUTION IN ERYTHROCYTE MEMBRANES (HYPERBARIC OXYGENATION IN AIR POLLUTION)

Abstract

Aim: The aim was to investigate the interactions of hyperbaric oxygenation (HBO) and sulphur dioxide (SO2) inhalation (at 10 ppm, one hour daily for 45 days) on lipoperoxidation and fragility of RBC membranes. Methods: Malonyldialdehyde (MDA) levels, osmotic fragility ratios and hematologic parameters of a total of 24 rats were compared in four different groups controls, HBO, SO2 and (HBO+SO2). HBO was applied at 3 Atm abs (303.9 kPa), 1 hour daily, for 45 days in a specifically designed exposure chamber. Results: MDA levels and osmotic fragility ratios were significantly higher in groups-B, C and D than in control group (p

Keywords

• HBO, SO2, RBC, lipoperoxidation, fragility

References

1. Myers RA. Hyperbaric oxygen therapy, a commitee report. Bethesda, Md: Undersea Medical Society, 1986:30-72
2. Saltzman HA. Use of hyperbaric oxygen in cardiovascular disease. Mod Concepts Cardiovasc Dis 1966;35:87-92
3. Dundar K, Topal T, Ay H, Oter S, Korkmaz A. Protective effects of exogenously administered or endogenously produced melatonin on hyperbaric oxygen-induced oxidative stress in the rat brain. Clin Exp Pharmacol Physiol 2005;11:926-30
4. Edremitlioglu M, Kilic D, Oter S et al. The effect of hyperbaric oxygen treatment on the renal functions in septic rats: relation to oxidative damage. Surg Today 2005;8:653-61.
5. Nylander G, Otamiri T, Lewis DH, Larsson J. Lipid peroxidation products in postischemic skeletal muscle and after treatment with hyperbaric oxygen. Scand J Plas Reconstr Surg 1989; 23:97-103
6. Topal T, Oter S, Korkmaz A et al. Exogenously endogenously produced melatonin reduce hyperbaric oxygen-induced oxidative stress in rat lung. Life Sci. 2004;4:461-7
7. Beneditti S, Lamorgese A, Piersantelli M, Pagliarani S, Benvenuti F, Canestrari F. Oxidative stress and antioxidant status in patients undergoing prolonged exposure to hyperbaric oxygen. Clin Biochem. 2004;4:312-7
8. Etlik O, Tomur A, Dundar K, Erdem A, Gundogan NU. The efect of antioxidant vitamins E and C on lipoperoxidation of erythrocyte membranes during hyperbaric oxygenation. J Basic Clin Physiol Pharmacol. 1997;4:269-77

9. Monstrey SJ, Mullick P, Narayanan K, Ramassastry SS. Hyperbaric oxygen therapy and free radical production: an experimental study in doxorubicin (adriamycin) extravasation injuries. Ann Plast Surg. 1997; 2:163-8
10. Tomur A, Etlik O, Gundogan NU. Hyperbaric oxygenation and antioxidan vitamin combination reduces ischemia- reperfusion injury in a rat epigastric island skin-flap model. J Basic Clin Physiol Pharmacol. 2005;4:275-85
11. Ogawa A, Kawakami A, Yagi T, Amay T, Fujise H, Takahashi R. Oxidative damage to the membrane of canine erythrocyteswith inherited high Na, K- ATPase activitiy. J Vet Med Sci 1992; 54: 57-62
12. Roelofsen B, van Deenen LLM. Lipid requirement of membrane-bound ATPase: Studies on human erythrocyte. Eur J Biochem 1973; 40:245
13. Noda Y, McGeer PL, McGeer EG. Lipid peroxide distribution in brain and the effect of hyperbaric oxygen. J Neurochem. 1983; 40:1329-32
14. Nohl H, Hegner D, Summer KH. The mechanism of toxic action af hyperbaric oxygenation on the mitochondria of rat heart cells. Biochem Pharmacol 1981; 30:1753-7
15. Kovachich GB, Mishra OP, Clark JM. Depression of cortical Na+, K+-ATPase activity in rats exposed to hyperbaric oxygen. Brain Res 1981; 206:229-32
16. Knight JA, Voorhees RP, Martin L. The effect of metal chelators on lipid peroxidation in stored erythrocytes. Ann Clin Lab Sci. 1992; 22:207-13
17. Advani R, Rubin E, Mohandas N, Schrier SL. Oxidative red blood cell membrane injury in the pathophysiology of severe mouse beta-thalessemia. Blood 1992; 79: 1064-7
18. Chen MJ, Sorette MP, Chiu DT, Clark MR. Prehemolytic effects of hydrogen peroxide and t-butylhydroperoxide on selected red cell properties. Biochim Biophys Acta 1991; 1066:193-200
19. Bystrova TA. Effects of sulfur dioxide studied with the use of labeled atoms.Gig. i Sanit.1957;20:30-37. in: USSR literature on air pollution and related occupational diseases, A survey , vol. 1, translated by Levine BS, US dept. of Commerce, Office of technical Services, Washington, D. C., 1960, 89-97
20. Balchum, O.J., Dybicki, J., Meneely, G.R. Measurement of pulmonary resistance and compliance with concurrent tissue radioactive sulfur distributions in dogs inhaling a labeled air pollutant- sulfur dioxide. Fed Proc 1959;18:6
21. Balchum, O.J., Dybicki, J., Meneely, G.R. The dynamics of sulfur dioxide inhalation. A.M.A. Archives Of Industrial Health 1960;21:564-8
22. Haider, SS. Effects of exhaust pollutant sulfur dioxide on lipid metabolism of guinea pig organs. Ind Health 1985;23: 81-7
23. Medeiros MHG, Bechara EJH, Naoum PC, Mourao CA. Oxygen toxicity and hemoglobinemia in subjects from ahighly polluted town. Arch Anviron Health 1983;38:11-6
24. Dikmenoglu N, Baskurt OK, Levi E, Çaglayan S, Guler S. How does sulphur dioxide affect erythrocyte deformability. Clin Hemorheol 1991;11:497-9
25. Baskurt OK, Balkanci D, Andac SO, Yorukan S. Hava kirliliginin hemoglobin ve hematokrit degerlerine etkisi. Turkish J Res Med Sci 1987;5:211-6
26. Meng Z, Zhang B, Bai J, Geng H, Liu C. Oxidative damage of sulfur dioxide inhalation on stomachs and intestines of mice. Inhal Toxicol 2003;15:397-410
27. Agar A, Kucukatay V, Yargicoglu P, Bilmen S, Gumuslu S, Yucel G. Effect of sulfur dioxide inhalation on erythrocyte antioxidant status and lipid peroxidation in experimental diabetes. Diabetes Metab 2000; 26:140-4
28. Lutz J, Stark M. Administration of perfluorochemicals under hyperbaric oxgen pressure and treatment with free oxgen radical scavengers. Biomat Art Cells Art Org 1988;16:395-402
29. Stocks J, Dormandy TL. The autoxidation of human red cell lipids induced by hydrogen peroxide. British Journal of Haemotology 1971;20:95-111
30. Stocks J, Offerman CB, Modell CB, Dormandy TL. The susceptibility to autoxidation of human red cell lipids in health and disease. Br J Haemotol 1972;23:713-24
31. Parpart AK, Lorenz PB, Parpart ER, Gregg JR, Chase AM. The osmotic resistance (fragility) of human red cells. J Clin Invest 1947;26:636
32. Marklund SL, Holme E, Hellner L. Superoxide dismutase in extracellular fluids. Clin Chim Acta 1982;126:41-51
33. Dise CA, Clark JM, Lambersten CJ, Goodman DBP. Hyperbaric hyperoxia reversibly phospholipid fatty acid turnover. J Appl Physiol 1987; 62:533-8 erythrocyte
34. Debouzy JC, Fauvelle F, Vezin H, Brasme B, Chancerelle Y. Interaction of the malonyldialdehyde molecule with membranes. Biochem Pharmacol 1991;44:1787-9 48. Jain SK. malonyldialdehyde, fatty acid peroxidation, can disturb aminophospholipid organization in the membrane bilayer of human erythrocytes. J Biol Chem 1984;259:3391-94 of of product
35. Snyder LM, Fortier NL, Trainor J, Jacobs J, Leb L. Effect of hydrogen peroxide exposure on normal human erythrocyte deformability, characteristics, and spectrin-hemoglobin crosslinking. J Clin Invest 1985;76:1971- 77 surface
36. Snyder LM, Fortier NL, Leb L et al. The role of membrane protein sulfhydryl groups in hydrogen peroxide-mediated membrane damage in human erythrocytes. Biochim Biophys Acta 1988;937:229-40
37. Harabin AL, Braisted JC, Flynn ET. Response of antioxidant enzymes to intermittent and continuous hyperbaric oxygen. J Appl Physiol 1990; 69:328-35
38. Jain KK. Hyperbaric oxygen Therapy in hematology and immunization. Textbook of hyberbaric medicine. Hogrefe&Huber publishers. 1990:309-17
39. Ball COT, Heyssel RM, Balchum OJ, Elliot GO, Meneely GR. Survival of rats chronically exposed to sulfur dioxide. The Physiologist.1960;3:15.
40. Kapalin VL.The red blood picture in children from different environments. Rev Czech Med 963;9:65-81
41. Said SI. Environmental injury of the lung: Role of humoral mediators. Federation Proceedings 1978;37:2504-7
42. Erdmann AJ, Huttemeier PC, Landolt C, Zapol WM. Pure oxygen breathing increases sheep lung microvascular permeability. Anesthesiol 1983;58:153-8 57. Wintrobe MM. Hemoglobin and erythrocyte Hematology (8th ed.), Phiadelphia 1981: 80-107 Clinical
43. Corn M, Burton G. The irritant potential of pollutants in the atmosphere. Arch Environ Health 1967;14:54-61
44. Harkonen H, Nordman H, Korhonen O, Winblad I. Long-term effect of exposure to sulfur dioxide. Am Rev Respir Dis 1983;128:890-3
45. Buxton JT, Stallworth JM, Bradham GB. Hematocrit changes under hyperbaric oxgen. Am Surg 1964;30:18-22 61. Biriukov IB, Tsygankova ST, BronskaiaLK, Namazbekov BK, Akimova NI. Immunological indicators as the criteria of prognosis and treatment of nonspesific diseases of the lungs and pleura. Vestn Khir 1988; 140:10-13
46. Lotovin AP, Morozov VG, Khavinson VK. On the problem of cellular and humoral activity under conditions of hyperoxia. in: Yefuni SN (ed) Proceedings of the 7th internatinale congress on hyperbaric medicine. USSR Academy of Sciences, Moscow 1981:399
47. Claster S, Chiu DT, Quintanilha A, Lubin B. Neutrophils mediate lipid peroxidation in human red cells. Blood 1984; 64:1079- 84 64. Mottley C, Harman RP.Microsomal reduction of bisulfit (Aqueous dioxide anion free radical formation by cytochrome P-450. Biochem Pharmacol 1985,34:3005-8 LS, Mason sulfur dioxide)-Sulfur
48. Burlamacchi L, Casini G, Fagioli O, Tiezzi E. The air oxidation of free radicals to form superoxide and regenerate bisulfite. Ricercea scient 1967;37:97
49. Aust SD, Roerig DL, Pederson TC. Evidence for superoxide generation by NADPH-cytocrome C reductase of rat liver microsomes. Biochem Biophys Res Commun 1972;47:1133
50. Mishin V, Pokrovsky A, Lyakhovich VV.Interactions of some acceptors with superoxide anione radicals formed by the NADPH-specific flavoprotein in rat liver microsomal fractions. Biochem J 1976; 154:307