The congenital muscular dystrophies (CMD) are autosomal-recessive disorders. Classical congenital muscular dystrophy is grouped as merosin-positive and merosin-negative (MN-CMD). Precocious puberty is idiopathic and is related to premature release of gonadotrophins. So far, the association between merosin deficiency and precocious puberty has not been identified. We report a case of a child with precocious puberty who was diagnosed with merosin deficiency in infancy.
Konjenital müsküler distrofiler (CMD) otozomal resesif kalıtılan hastalıklardır. Klasik konjenital müsküler distrofi merosinpozitif ve merosin-negatif olarak gruplandırılır (MN-CMD). Kızlarda puberte prekoks 1969 yılında Marshal ve Tanner tarafından tanımlanmıştır. Olguların çoğunda, puberte prekoks idiyopatiktir ve gonadotropinlerin erken salınımı ile ilgilidir. Şimdiye kadar, merosin eksikliği ve puberte prekoks arasındaki ilişki tanımlanmamıştır. Bu yazıda infantil dönemde merosin eksikliği tanısı konulan puberte prekokslu bir çocuğu sunduk
Eklioglu, B. S., Akyurek, N., Yuca, S. A., Atabek, M. E. (2015). Partial Merosin Deficiency and Precocious Puberty. European Journal of General Medicine, 12(1). https://doi.org/10.15197/sabad.1.12.18
AMA
Eklioglu BS, Akyurek N, Yuca SA, Atabek ME. Partial Merosin Deficiency and Precocious Puberty. European Journal of General Medicine. March 2015;12(1). doi:10.15197/sabad.1.12.18
Chicago
Eklioglu, Beray Selver, Nesibe Akyurek, Sevil Arı Yuca, and Mehmet Emre Atabek. “Partial Merosin Deficiency and Precocious Puberty”. European Journal of General Medicine 12, no. 1 (March 2015). https://doi.org/10.15197/sabad.1.12.18.
EndNote
Eklioglu BS, Akyurek N, Yuca SA, Atabek ME (March 1, 2015) Partial Merosin Deficiency and Precocious Puberty. European Journal of General Medicine 12 1
IEEE
B. S. Eklioglu, N. Akyurek, S. A. Yuca, and M. E. Atabek, “Partial Merosin Deficiency and Precocious Puberty”, European Journal of General Medicine, vol. 12, no. 1, 2015, doi: 10.15197/sabad.1.12.18.
ISNAD
Eklioglu, Beray Selver et al. “Partial Merosin Deficiency and Precocious Puberty”. European Journal of General Medicine 12/1 (March 2015). https://doi.org/10.15197/sabad.1.12.18.
JAMA
Eklioglu BS, Akyurek N, Yuca SA, Atabek ME. Partial Merosin Deficiency and Precocious Puberty. European Journal of General Medicine. 2015;12. doi:10.15197/sabad.1.12.18.
MLA
Eklioglu, Beray Selver et al. “Partial Merosin Deficiency and Precocious Puberty”. European Journal of General Medicine, vol. 12, no. 1, 2015, doi:10.15197/sabad.1.12.18.
Vancouver
Eklioglu BS, Akyurek N, Yuca SA, Atabek ME. Partial Merosin Deficiency and Precocious Puberty. European Journal of General Medicine. 2015;12(1).