MEPERIDINE, AS AN EFFECTIVE ADJUVANT AGENTIN UNILATERAL SPINAL ANAESTHESIA FOR KNEE ARTHROSCOPY

Year 2008, Volume: 5 Issue: 1, 36 - 41, 01.03.2008

Height Cm

Abstract

-

Keywords

-

MEPERIDINE, AS AN EFFECTIVE ADJUVANT AGENTIN UNILATERAL SPINAL ANAESTHESIA FOR KNEE ARTHROSCOPY

Abstract

Aim: Unilateral spinal anaesthesia permits early recovery and short ambulatory stay. Our study aimed to search if meperidine may prolong sensory block time when added to hyperbaric bupivacaine. Methods: This is a prospective, double blinded study: Ambulatory, 46 consenting patients aged 18-60 years, undergoing unilateral knee arthroscopy were randomized in two groups. saline group (n=20): 1.3 ml of hyperbaric bupivacaine and 0.2 ml of serum physiologic was used. Meperidine group (n=20): 1.3 ml of hyperbaric bupivacaine and 0.2 ml of 5% meperidine was used. Sensory block times, duration of spinal anaesthesia, intraoperative adverse effects and patient satisfaction were recorded. Results: Mean duration of sensory block was greater in the meperidine group compared with the saline group. Strict unilateral block and hypotension were comparable among groups. Conclusion: Addition of meperidine to hyperbaric bupivacaine in unilateral spinal anaesthesia prolonged analgesia without effecting total anesthesia time with minimal adverse effects

Keywords

Unilateral spinal anaesthesia, meperidine, outpatient surgery, knee arthroscopy

References

• Urmey WF. Spinal anesthesia for outpatient surgery. Best Pract Res Clin Anaesthesiol 2003;17:335–46
• Liu SS. Optimizing Spinal Anesthesia for Ambulatory Surgery. Reg Anesth 1997;22: 500-10
• Fanelli G, Borghi B, Casati A, Bertini L, Montebugnoli M, Torri G. Unilateral bupivacaine spinal anesthesia for outpatient knee arthroscopy. Can J Anesth 2000;47: 746-51
• Fanelli G, Casati A, Aldegheri G, et al. Cardiovascular effects of two different regionel anaesthetic techniques for unilateral leg surgery. Acta Anaesthesiol Scand 1998;42:80-4
• Kuusniemi K, Pihlajamaki K, Pitkanen MT. A low dose of plain and hyperbaric bupivacaine for unilateral spinal anesthesia. Reg Anesth Pain Med 2000;25:605-10
• Iselin-Chaves IA, VanGessel EF, Donald FA, Forster A, Gamulin Z. The effects of solution concentration and epinephrine on lateral distribution of hyperbaric tetracaine spinal anesthesia. Anesth Analg 1996;83:755-9
• Liu S, Chiu A, Carpenter RL, et al. Fentanyl prolongs lidocaine spinal anesthesia without prolonging recovery. Anesth Analg 1995;80: 730-4
• Tsen LC, Schultz R, Martin R, Data S, Bader AM. Intrathecal low dose bupivacaine versus lidocaine for in vitro fertilization procedures. Reg Anesth Pain Med 2001;26:52-6
• Yu SC, Ngan Kee WD, Kwan ASK. Addition of meperidine to bupivacaine for spinal anesthesia for Caesarean section. Br J Anaesth 2002;88:379-83
• Casati A, Fanelli G, Cappelgeri G, Leoni A et al. Does speed of intrathecal injection effect the distribution of % 0.5 hyperbaric bupivacaine? Br J Anaesth 1998;81:355-7
• Newel R. Pelvic girdle and lower limb. In: Standring S, Editor. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. Madrid: Elsevier Churchill Livingstone, 2005: 1413-4
• Gerancher JC, Liu SS. Complications of anesthesia. In: Benumof JL, Saidman LJ, Editors. Anesthesia and perioperative complications. St. Louis: Mosby Co, 1999: 50-65
• Sumi M, Sakura S, Koshizaki M, Saito Y, Kosaka Y. The advantages of the lateral decubitus position after spinal anesthesia with hyperbaric tetracaine. Anesth Analg 1998;87:879-84
• Gentili ME. Added morphine may spoil unilateral spinal block. Reg Anesth Pain Med 2005;30:596
• Gentili ME,Mamelle JC, Le Foll G. Combination of low dose bupivacaine and clonidine for unilateral spinal anesthesia in arthroscopic knee surgery. Reg Anesth 1995;20:169-70
• Casati A, Fanelli G, Cappelleri G, et al. Effects of spinal needle type on lateral distribution of % 0.5 hyperbaric bupivacaine. Anesth Analg 1998;87:355-9
• Enk D, Prien T, Van Aken H, Metres N, Meyer J, Brüssel T. Success rate of unilateral spinal anesthesia is dependent on injection flow. Reg Anesth Pain Med 2001;26:420-7.
• Kafle SK. Intrathecal meperidine for Caesarean section: a comparison with lidocaine. Can J Anaesth 1993;40:718-21
• Roy JD, Girard M, Drolet P. Intrathecal meperidine decreases shivering during cesarean delivery under spinal anesthesia. Anesth Analg 2004;98:230-4