Urticaria; An Uncommon Presentation Of Thyrotoxicosis

Year 2007, Volume: 4 Issue: 4, 205 - 208, 01.12.2007

Karthik Prabhakar David James Tymms

Abstract

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Keywords

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Urticaria; An Uncommon Presentation Of Thyrotoxicosis

Abstract

Royal Albert Edward Infirmary, Diabetes Centre, Department of Medicine, Wigan UK We describe below two patients who presented with thyrotoxicosis and were put on carbimazole treatment. Both of them developed urticarial rash following commencement of carbimazole treatment. The drug was stopped but the patients continued to have the rash for a few months. One patient became biochemically hypothyroid despite cessation of treatment but again became biochemically and clinically hyperthyroid and subsequently underwent radioactive iodine treatment. The other patient was treated with propylthiouracil and became euthyroid. It was found that the urticaria improved in both patients as their overactive thyroid status got better

Keywords

Thyrotoxicosis, urticaria, carbimazole, propylthiouracil

References

• Mousa AM, Knight G. Urticaria The Presenting Symptom Of Thyrotoxicosis. Endocrine Abstracts(2003) 6 P76
• Pace JL, Garretts M. Urticaria and hyperthyroidism. Br J Dermatol 1975;93(1):97
• Henderson CA, Highet AS. Urtcaria associated with thyrotoxicosis. Clin Exp Dermatol 1995;20(2):173-4
• Delevaux I, Andre M, Tridon A, Aumaitre O. Chronic urticaria and Hashimoto- Hashimoto’s thyroiditis: report of 6 cases.Rev Med Interne 2001;22(3):232-7
• Amoroso A, Garzia P, Pasquarelli C, Sportelli G, Afeltra A. Hashimoto’s thyroiditis associated with urticaria and angio-oedema : disappearance of cutaneous and mucosal manifestations after thyroidectomy. J Clin Pathol 1997; 50(3):254-6
• Zauli D, Deleonardi G, Foderaro S, Grassi A, Bortolotti R, Ballardini G et al. Thyroid autoimmunity in chronic urticaria. Allergy Asthma Proc 2001;22: 93-5