LOCALIZED VOCAL CORD AMYLOIDOSIS

Year 2007, Volume: 4 Issue: 1, - , 01.03.2007

Ayşe Cefle Ayten Yazıcı Kazım Sepetçigil Kürşat Yıldız

Abstract

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Keywords

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LOCALIZED VOCAL CORD AMYLOIDOSIS

Abstract

Kocaeli University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Internal Medicine and Pathology. Kocaeli, Turkey Localized laryngeal amyloidosis is an uncommon diease with limited long-term follow- up studies. The precise etiology and pathogenesis are not entirely clear. We present a case of localized laryngeal amyloidosis. 35 years old man suffered from hoarseness during the last six months. Laryngoscopic examination showed nodular infiltration of bilateral vocal cords. Amyloidosis was confirmed by the characteristic Congo red staining of biopsies. The search for other localizations of amyloidosis was negative. No evidence of systemic amyloidosis or plasma cell proliferation was found in this patient. There were no recurrences during the nine-months follow-up

Keywords

Amyloidosis, localized, larynx, vocal cords

References

• Siddachari RC, Chaukar DA, Pramesh CS, Naresh KN, de Souza CE, Dcruz AK. Laryngeal amyloidosis. J Otolaryngol 2005;34(1):60-3
• Gillmore JD, Hawkins PN. Amyloidosis and the respiratory tract. Thorax 1999; 54:444-51
• Ma L, Bandarchi B, Sasaki C, Levine S, Choi Y. Primary localized laryngeal amyloidosis: report of 3 cases with long-termfollow-up and review of the literature. Arch Pathol Lab Med 2005; 129(2):215-8
• Benson MD. Amyloidosis. In: Koopman WJ, Moreland LW, eds. Arthritis and Allied Conditions. A Textbook of Rheumatology. Fifteenth ed. Philadelphia: Lippincott Williams Wilkins, 2005:1933- 60
• Monroe AT, Walia R, Zlotecki RA, Jantz MA. Tracheobronchial amyloidosis. A case report of successful treatment with external beam radiation therapy. Chest 2004;125:784-9
• Hamidi Asl K, Liepnieks JJ, Nakamura M, et al. Organ specific (localized) synthesis of Ig light chain amyloid. J Immunol 1999;162:5556-60
• Troxler RF, Kane K, Berg AM, et al. Localised amyloidosis of the larynx: evidence for light chain composition. Ann Otol Rhinol Laryngol 1993;102:884-9
• Bartels H, Dikkers FG, van der Wal JE, Lokhorst HM, Hazenberg BP. Laryngeal amyloidosis: localized versus systemic disease and update on diagnosis and therapy. Ann Otol Rhinol Laryngol 2004; 113(9):741-8
• Motta G, Salzano FA, Motta S, Staibano S. CO (2)-laser treatment of laryngeal amyloidosis. J Laryngol Otol 2003; 117(8):647-50
• Alaani A, Warfield AT, Pracy JP. Management of laryngeal amyloidosis. J Laryngol Otol 2004;118(4):279-83
• Pribitkin E, Friedman O, O’hara B, et al. Amyloidosis of the upper aerodigestive tract. Laryngoscope 2003;113(12):2095- 101 Cefle and Yazıcı