This paper reports a 74 year-old-man with a hypertrophic cardiomyopathy associated with mid-ventricular obstruction and a secundum type atrial septal defect. He had been suffering from shortness of breath and occasional attacks of dizziness. Doppler echocardiography revealed the gradient in the mid-left ventricular area. A transesophageal echocardiogram confirmed the findings of transthoracic study and an ostium secundum-type atrial septal defect was documented. The present case represents a rare combination of hypertrophic cardiomyopathy associated with midventricular obstruction, and an ostium secundum type atrial septal defect in an elderly man. Key words: Hypertrophic cardiomyopathy, midventricular obstruction, atrial septal defect.
Falicov RE, Resnekov L. Mid ventricular obstruction in hypertrophic obstructive cardiomyopathy. New diagnostic and therapeutic challenge. Br Heart J 1977;39(7):701-5
Thierfelder L, Watkins H, MacRae C et al. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell 1994;77(5):701-12
Coviello DA, Maron BJ, Spirito P et al. Clinical features of hypertrophic cardiomyopathy caused by mutation of a “hot spot” in the alpha-tropomyosin gene. J Am Coll Cardiol 1997;29(3):635-40
Falicov RE, Resnekov L , Bharati S, Lev M. Mid-ventricular obstruction: a variant of obstructive cardiomyopathy. Am J Cardiol. 1976;37(3):432-7
Wigle ED, Sasson Z, Henderson MA et al. Hypertrophic cardiomyopathy. The importance of the site and the extent of hypertrophy. A review. Prog Cardiovasc Dis 1985;28(1):1-83
Forker AD, Morgan JR. Hypertrophic subaortic stenosis with ostium secundum atrial septal defect. Chest 1971;60:512-5
Hernandez-Reyes P, Espinola-Zavaleta N, Vargas-Barron J, Romero-Cardenas A, Nonobstructive hypertrophy and ostium secundum-type atrial septal defect. Echocardiography 2000;17(8):725-9 J, asymmetrical septal
Long JL, Nourissat JL, Normand J, Michaud P. Association of an interauricular communication of the sinus venosus type with obstructive myocardiopathy. Surgical treatment. Arch Mal Coeur Vaiss 1984;77(2):222-7
Smith DC, Vieweg WV, Folkerth TL, Hagan AD. Idiopathic hypertrophic subaortic stenosis with ostium secundum atrial septal defect: successful surgical correction. Chest 1975;68(2):246-8
Branco LM, Quininha J, Roquette J et al. Hypertrophic non-obstructive cardiomyopathy interauricular communication. Report of a case. Rev Port Cardiol 19909(5):449-53
HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT
Year 2005,
Volume: 2 Issue: 3, 129 - 131, 01.09.2005
Falicov RE, Resnekov L. Mid ventricular obstruction in hypertrophic obstructive cardiomyopathy. New diagnostic and therapeutic challenge. Br Heart J 1977;39(7):701-5
Thierfelder L, Watkins H, MacRae C et al. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell 1994;77(5):701-12
Coviello DA, Maron BJ, Spirito P et al. Clinical features of hypertrophic cardiomyopathy caused by mutation of a “hot spot” in the alpha-tropomyosin gene. J Am Coll Cardiol 1997;29(3):635-40
Falicov RE, Resnekov L , Bharati S, Lev M. Mid-ventricular obstruction: a variant of obstructive cardiomyopathy. Am J Cardiol. 1976;37(3):432-7
Wigle ED, Sasson Z, Henderson MA et al. Hypertrophic cardiomyopathy. The importance of the site and the extent of hypertrophy. A review. Prog Cardiovasc Dis 1985;28(1):1-83
Forker AD, Morgan JR. Hypertrophic subaortic stenosis with ostium secundum atrial septal defect. Chest 1971;60:512-5
Hernandez-Reyes P, Espinola-Zavaleta N, Vargas-Barron J, Romero-Cardenas A, Nonobstructive hypertrophy and ostium secundum-type atrial septal defect. Echocardiography 2000;17(8):725-9 J, asymmetrical septal
Long JL, Nourissat JL, Normand J, Michaud P. Association of an interauricular communication of the sinus venosus type with obstructive myocardiopathy. Surgical treatment. Arch Mal Coeur Vaiss 1984;77(2):222-7
Smith DC, Vieweg WV, Folkerth TL, Hagan AD. Idiopathic hypertrophic subaortic stenosis with ostium secundum atrial septal defect: successful surgical correction. Chest 1975;68(2):246-8
Branco LM, Quininha J, Roquette J et al. Hypertrophic non-obstructive cardiomyopathy interauricular communication. Report of a case. Rev Port Cardiol 19909(5):449-53
Aydın, M., Doğan, S. M., Gürsürer, M., Onuk, T., et al. (2005). HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT. European Journal of General Medicine, 2(3), 129-131.
AMA
Aydın M, Doğan SM, Gürsürer M, Onuk T, Dursun A, Cam F. HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT. European Journal of General Medicine. September 2005;2(3):129-131.
Chicago
Aydın, Mustafa, Sait Mesut Doğan, Metin Gürsürer, Tolga Onuk, Aydın Dursun, and Fatih Cam. “HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT”. European Journal of General Medicine 2, no. 3 (September 2005): 129-31.
EndNote
Aydın M, Doğan SM, Gürsürer M, Onuk T, Dursun A, Cam F (September 1, 2005) HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT. European Journal of General Medicine 2 3 129–131.
IEEE
M. Aydın, S. M. Doğan, M. Gürsürer, T. Onuk, A. Dursun, and F. Cam, “HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT”, European Journal of General Medicine, vol. 2, no. 3, pp. 129–131, 2005.
ISNAD
Aydın, Mustafa et al. “HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT”. European Journal of General Medicine 2/3 (September 2005), 129-131.
JAMA
Aydın M, Doğan SM, Gürsürer M, Onuk T, Dursun A, Cam F. HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT. European Journal of General Medicine. 2005;2:129–131.
MLA
Aydın, Mustafa et al. “HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT”. European Journal of General Medicine, vol. 2, no. 3, 2005, pp. 129-31.
Vancouver
Aydın M, Doğan SM, Gürsürer M, Onuk T, Dursun A, Cam F. HYPERTROPHIC CARDIOMYOPATHY WITH MIDVENTRICULAR OBSTRUCTION IN ASSOCIATION WITH OSTIUM SECUNDUM-TYPE ATRIAL SEPTAL DEFECT. European Journal of General Medicine. 2005;2(3):129-31.