Research Article
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Year 2022, Volume: 1 Issue: 2, 63 - 79, 10.11.2022
https://doi.org/10.55971/EJLS.1181461

Abstract

References

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  • 3. González-Burgos E, Carretero M E, Gómez-Serranillos M P, Sideritis spp.: Uses, chemical composition and pharmacological activities—A review. Journal of Ethnopharmacology. (2011); 135: 209-225.
  • 4. Güner A, Aslan S, Ekim T, Vural M, Babaç M T ve ark. Türkiye Bitkileri Listesi (Damarlı Bitkiler). İstanbul: Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını; (2012).
  • 5. Kirimer N, Tabanca N, Özek T, Tümen G, Baser K H C. Essential Oils of Annual Sideritis Species Growing in Turkey. Pharmaceutical Biology. 2000; 38(2):106–111.
  • 6. Alipieva K I, Kostadinova E P, Evstatieva L N, Stefova M, Bankova V S. An iridoid and a flavonoid from Sideritis lanata L. Fitoterapia 80. 2009; 51-53.
  • 7. Ugur A, Varol O, Ceylan O. Antibacterial Activity of Sideritis curvidens and Sideritis lanata from Turkey. Pharmaceutical Biology. 2005; 43(1): 47-52.
  • 8. Adams RP. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. Allured Publ. Corp, Carol Stream, IL. (2007) ISBN 978-1-932633-11-4
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  • 12. Kumarasamy Y, Byres M, Cox PJ, Jaspars M, Nahar L, Sarker SD. Screening seeds of some Scottish plants for free radical scavenging activity. Phytother. Res. (2007); 21 (7): 615-621.
  • 13. Singleton V L, Orthofer R, Lamuela-Raventós R M. Analysis of total phenols and other oxidation substrates and antioxidants by means of folinciocalteu reagent. Meth. Enzymol. (1999);299: 152-178.
  • 14. Kosar M, Göger F, Can Baser K H. In vitro antioxidant properties and phenolic composition of Salvia virgata Jacq. from Turkey. J. Agric. Food Chem. (2008); 56 (7): 2369-2374.
  • 15. Koutsaviti A, Bazos I, Milenković M, Pavlović-Drobac M, Tzakou O. Antimicrobial Activity and Essential Oil Composition of Five Sideritis taxa of Empedoclia and Hesiodia Sect. from Greece. Records of Natural Products. (2013); 7(1): 6-14.
  • 16. Stanoeva J P, Stefova M, Stefkov G, Kulevanova S, Alipieva K, Bankova V, Aneva I, Evstatieva L N. Chemotaxonomic contribution to the Sideritis species dilemma on the Balkans. Biochemical Systematics and Ecology. (2015); 61:477-487.
  • 17. Kirici D, Saltan N, Goger F, Kose Y B, Demirci B. Chemical compositions of Sideritis albiflora Hub. – Mor. İstanbul Journal of Pharmacy. (2021); 51(3): 378-385.
  • 18. Koleva I I, Linssen J P H, van Beek T A, Evstatieva L N, Kortenska V, Handjieva N. Antioxidant activity screening of extracts from Sideritis species (Labiatae) grown in Bulgaria. Journal of the Science of Food and Agriculture. (2003); 83:809–819. DOI: 10.1002/jsfa.1415.
  • 19. Güvenç A, Houghton P J, Duman H, Coşkun M, Şahin P. Antioxidant Activity Studies on Selected Sideritis Species Native to Turkey. Pharmaceutical Biology. (2005); 43(2):173–177.

Antimicrobial and antioxidant activities of Sideritis lanata L. extracts

Year 2022, Volume: 1 Issue: 2, 63 - 79, 10.11.2022
https://doi.org/10.55971/EJLS.1181461

Abstract

Sideritis L. (Lamiaceae) is represented by 45 species in Flora of Turkey. Sideritis lanata L. (Hairy ironwort) is located in the north-west, west, south-west and central Anatolia. Mountain tea (Sideritis plants) is used as a traditional remedy against common cold and gastrointestinal disorders. Its beneficial properties are attributed to its rich bioactive constituents. In this study, the antioxidant activities of the extracts of Sideritis lanata prepared using different solvents (n-hexane, ethyl acetate, and 70% ethanol) from the aerial parts were determined by DPPH· scavenging effect assay. Also; determined of the antimicrobial activity of S. lanata extracts against 4 bacteria and 5 Candida species. Dried aerial parts of Sideritis were subjected to hydrodistillation and the oil obtained was analyzed by using GC and GC/MS. S. lanata extracts prepared with 70% ethanol was found to have a higher DPPH· scavenging activity (IC50= 0.241 mg/mL) than extracts prepared with other solvents. All extracts showed generally weak inhibitory effects (500-8000 μg/mL, MIC) against bacterial strains. Inhibitory doses against the tested Candida species were determined between 125-4000 μg/mL. The 70% ethanol extract of S. lanata inhibited Candida tropicalis (ATCC 750) (MIC: 125 μg/mL).

References

  • 1. https://www.bizimbitkiler.org.tr/v2/index.php
  • 2. Çarıkçı S, Kılıç T, Azizoğlu A, Gülaçtı T. Chemical Constituents of Two Endemic Sideritis Species from Turkey with Antioxidant Activity. Record of Natural Products. 2012; 6(2): 101-109.
  • 3. González-Burgos E, Carretero M E, Gómez-Serranillos M P, Sideritis spp.: Uses, chemical composition and pharmacological activities—A review. Journal of Ethnopharmacology. (2011); 135: 209-225.
  • 4. Güner A, Aslan S, Ekim T, Vural M, Babaç M T ve ark. Türkiye Bitkileri Listesi (Damarlı Bitkiler). İstanbul: Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını; (2012).
  • 5. Kirimer N, Tabanca N, Özek T, Tümen G, Baser K H C. Essential Oils of Annual Sideritis Species Growing in Turkey. Pharmaceutical Biology. 2000; 38(2):106–111.
  • 6. Alipieva K I, Kostadinova E P, Evstatieva L N, Stefova M, Bankova V S. An iridoid and a flavonoid from Sideritis lanata L. Fitoterapia 80. 2009; 51-53.
  • 7. Ugur A, Varol O, Ceylan O. Antibacterial Activity of Sideritis curvidens and Sideritis lanata from Turkey. Pharmaceutical Biology. 2005; 43(1): 47-52.
  • 8. Adams RP. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. Allured Publ. Corp, Carol Stream, IL. (2007) ISBN 978-1-932633-11-4
  • 9. Hochmuth DH. MassFinder-4, Hochmuth Scientific Consulting, Hamburg, Germany. (2008).
  • 10. McLafferty FW, Stauffer DB. The Wiley/NBS Registry of Mass Spectral Data, J.Wiley and Sons: New York. (1989).
  • 11. Curvers J, Rijks J, Cramers C, Knauss K, Larson P. Temperature programmed retention indexes: calculation from isothermal data. Part 1: Theory. J High Resolut Chromatogr. (1985);8: 607–610. https://doi.org/10.1002/jhrc.1240080926
  • 12. Kumarasamy Y, Byres M, Cox PJ, Jaspars M, Nahar L, Sarker SD. Screening seeds of some Scottish plants for free radical scavenging activity. Phytother. Res. (2007); 21 (7): 615-621.
  • 13. Singleton V L, Orthofer R, Lamuela-Raventós R M. Analysis of total phenols and other oxidation substrates and antioxidants by means of folinciocalteu reagent. Meth. Enzymol. (1999);299: 152-178.
  • 14. Kosar M, Göger F, Can Baser K H. In vitro antioxidant properties and phenolic composition of Salvia virgata Jacq. from Turkey. J. Agric. Food Chem. (2008); 56 (7): 2369-2374.
  • 15. Koutsaviti A, Bazos I, Milenković M, Pavlović-Drobac M, Tzakou O. Antimicrobial Activity and Essential Oil Composition of Five Sideritis taxa of Empedoclia and Hesiodia Sect. from Greece. Records of Natural Products. (2013); 7(1): 6-14.
  • 16. Stanoeva J P, Stefova M, Stefkov G, Kulevanova S, Alipieva K, Bankova V, Aneva I, Evstatieva L N. Chemotaxonomic contribution to the Sideritis species dilemma on the Balkans. Biochemical Systematics and Ecology. (2015); 61:477-487.
  • 17. Kirici D, Saltan N, Goger F, Kose Y B, Demirci B. Chemical compositions of Sideritis albiflora Hub. – Mor. İstanbul Journal of Pharmacy. (2021); 51(3): 378-385.
  • 18. Koleva I I, Linssen J P H, van Beek T A, Evstatieva L N, Kortenska V, Handjieva N. Antioxidant activity screening of extracts from Sideritis species (Labiatae) grown in Bulgaria. Journal of the Science of Food and Agriculture. (2003); 83:809–819. DOI: 10.1002/jsfa.1415.
  • 19. Güvenç A, Houghton P J, Duman H, Coşkun M, Şahin P. Antioxidant Activity Studies on Selected Sideritis Species Native to Turkey. Pharmaceutical Biology. (2005); 43(2):173–177.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Research Articles
Authors

Zeynep GÜLCAN 0000-0002-4379-3253

Nagehan SALTAN

Gökalp İŞCAN

Mine KÜRKÇÜOĞLU

Yavuz Bülent KÖSE

Publication Date November 10, 2022
Submission Date September 28, 2022
Published in Issue Year 2022 Volume: 1 Issue: 2

Cite

Vancouver GÜLCAN Z, SALTAN N, İŞCAN G, KÜRKÇÜOĞLU M, KÖSE YB. Antimicrobial and antioxidant activities of Sideritis lanata L. extracts. Eur J Life Sci. 2022;1(2):63-79.