Characterization and Biofilm Inhibition Properties of Astragalus gummifer Crude

Ruhane Tosunoğlu; Muhammed Kürşad Coşkun; Aleyna Ertürk; Ayşenur Yazıcı

EN

Characterization and Biofilm Inhibition Properties of Astragalus gummifer Crude

Abstract

Astragalus species are widely recognized for their potent bioactive properties; however, the antibiofilm potential of Astragalus gummifer remains unexplored. In the present study, we assessed the antimicrobial and antibiofilm activity of A. gumnifer metabolic extracts against referenced bacterial and Candida strains. Plant material was collected from the Palandöken Mountain region in Erzurum, Turkey. The crude extract was obtained by methanol extraction and concentrated at 62 °C, followed by dissolution in distilled water for microdilution and crystal violet assays. In addition to these assays, untargeted metabolite profiling was performed on the methanolic extract. Fourier Transform Infrared Spectroscopy (FT-IR) and Quadrupole Time-of-Flight Liquid Chromatography–Mass Spectrometry (Q-TOF-LC/MS) analyses were employed for compound identification. A total of nine known secondary metabolites were successfully identified in the crude extract of A. gummifer.

Keywords

Astragallus gumnifer, , biofilm , Qtof lcms , Kristal violet

References

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Details

Primary Language

English

Subjects

Biochemistry and Cell Biology (Other)

Journal Section

Research Article

Authors

Ruhane Tosunoğlu ^*
0009-0001-1715-0094
Türkiye

Muhammed Kürşad Coşkun
0000-0002-7551-9523
Türkiye

Aleyna Ertürk
0009-0004-0996-2991
Türkiye

Ayşenur Yazıcı
0000-0002-3369-6791
Türkiye

Early Pub Date

July 21, 2025

Publication Date

July 13, 2025

Submission Date

April 7, 2025

Acceptance Date

July 8, 2025

Published in Issue

Year 2025 Volume: 4 Number: 1

IZ

https://izlik.org/JA92HF63ER

APA

Tosunoğlu, R., Coşkun, M. K., Ertürk, A., & Yazıcı, A. (2025). Characterization and Biofilm Inhibition Properties of Astragalus gummifer Crude. Eurasian Journal of Molecular and Biochemical Sciences, 4(1), 37-44. https://izlik.org/JA92HF63ER

Characterization and Biofilm Inhibition Properties of Astragalus gummifer Crude

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Characterization and Biofilm Inhibition Properties of Astragalus gummifer Crude

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Early Pub Date

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

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