Mandibular Distraksiyon Osteogenezinde Adjuvan Tedaviler: Hormonal ve Farmakolojik Ajanlar

Abstract

Distraksiyon osteogenezi traksiyon uygulanarak birbirinden uzaklaştırılan kemik segmentlerinin arasında oluşan kallusun yeni kemik formasyonuna dönüştüğü bir tekniktir ve maksillofasiyal bölgedeki çeşitli defektlerin tedavisinde kullanılır. Distraksiyon tekniğinin yumuşak dokular üzerinde önemli avantajlara sahiptir. Ancak tedavi süresinin uzun olması önemli bir dezavantajdır. Son yıllarda distraksiyon sürecini kısaltabilecek pek çok materyal ve metot üzerinde çalışmalar yapılmış, çeşitli hormonal proteinler, farmakolojik ajanların distraksiyon osteogenezinde başarılı olabileceği gösterilmiştir. Bu derlemede mandibular distraksiyon osteogenezinde araştırılan hormonal proteinlerin ve farmakolojik ajanların kapsamlı bir incelemesini sunduk.

Keywords

• distraksiyon
• adjuvan tedavi
• mandibular distraksiyon osteogenezi

References

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