Year 2023,
Volume: 2 Issue: 4, 94 - 96, 25.12.2023
Issa Al Azrı
Ahmed Al Hashmı
Hunaina Al Kındı
Mina George
Kaouther Baccouche
References
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cell angiofibroma. A distinctive orbital tumor in adults. Am
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angiofibroma of the buccal mucosa. Oral Surg Oral Med
Oral Pathol Oral Radiol. Endod. 1999 Dec;88(6):707-13.
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angiofibroma of the oral cavity: report of a new location
for a rare tumor. Oral Surg Oral Med Oral Pathol Oral
RadiolEndod. 1999 Nov;88(5):581-5.
- 4. de Andrade CR, Lopes MA, de Almeida OP, León JE, Mistro
F, Kignel S. Giant cell angiofibroma of the oral cavity: a
case report and review of the literature. Med Oral Patol
Oral Cir Bucal. 2008; 13:E540–E543.
- 5. Ajura Abdul Jalil, Lau Shin Hin. Oral giant cell
angiofibroma: A case report. Oral Surg Oral Med Oral
Pathol Oral Radiol.2015 March: E158.
- 6. Husek K, Vesel K. Extraorbital giant cell angiofibroma.
CeskPatol. 2002 Jul;38(3):117-20. 6. Qian YW, Malliah
R, Lee HJ, Das K,Mirani N, Hameed M. A t(12;17) in an
extraorbital giant cell angiofibroma. Cancer Genet
Cytogenet. 2006 Mar;165(2):157-60.
- 7. Thomas R, Banerjee SS, Eyden BP, Shanks JH, Bisset DL,
Hunt R, et al. A study of four cases of extra-orbital giant
cell angiofibromawith documentation of some unusual
features. Histopathology. 2001 Oct;39(4):390-6.
- 8. .Fletcher CD. Giant cell fibroblastoma of soft tissue: a
clinicopathological and immunohistochemical study.
Histopathology 1988;13:499-508.
- 9. Dalton WT, Zolliker AS, McCaughey WTE, Jacques J,
Kanerstein M. Localized primary tumors of the pleura.
Cancer 1979;44:1465-75.
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at unusual sites: analysis of a series. Histopathology
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Giant Cell Angiofibroma: A Rare Tumour in the Oral Cavity
Year 2023,
Volume: 2 Issue: 4, 94 - 96, 25.12.2023
Issa Al Azrı
Ahmed Al Hashmı
Hunaina Al Kındı
Mina George
Kaouther Baccouche
Abstract
Giant cell angiofibroma (GCA) was first described as a distinctive orbital soft-tissue tumour. It is now recognised that this rare
tumour can present in other anatomical regions including the oral cavity. Here, we report a case of a 26-year-old male with a
primary complaint of a painless solitary swelling on the right buccal mucosa. The lesion was surgically excised and a diagnosis
of GCA was made based on light microscopy and immunohistochemical (IHC) studies. At present, local excision with long-term
follow-up seems to be the most appropriate management modality. To the best of our knowledge, only four cases of GCA arising
in the oral cavity were reported in the literature.
References
- 1.Dei TA, Seregard S, Calonje E, Chan JK, Fletcher CD. Giant
cell angiofibroma. A distinctive orbital tumor in adults. Am
J SurgPathol 1995;19:1286-93.
- 2. Kintarak S, Natiella J, Aguirre A, Brooks J. Giant cell
angiofibroma of the buccal mucosa. Oral Surg Oral Med
Oral Pathol Oral Radiol. Endod. 1999 Dec;88(6):707-13.
- 3. Rousseau A, Perez-Ordonez B, Jordan RC. Giant cell
angiofibroma of the oral cavity: report of a new location
for a rare tumor. Oral Surg Oral Med Oral Pathol Oral
RadiolEndod. 1999 Nov;88(5):581-5.
- 4. de Andrade CR, Lopes MA, de Almeida OP, León JE, Mistro
F, Kignel S. Giant cell angiofibroma of the oral cavity: a
case report and review of the literature. Med Oral Patol
Oral Cir Bucal. 2008; 13:E540–E543.
- 5. Ajura Abdul Jalil, Lau Shin Hin. Oral giant cell
angiofibroma: A case report. Oral Surg Oral Med Oral
Pathol Oral Radiol.2015 March: E158.
- 6. Husek K, Vesel K. Extraorbital giant cell angiofibroma.
CeskPatol. 2002 Jul;38(3):117-20. 6. Qian YW, Malliah
R, Lee HJ, Das K,Mirani N, Hameed M. A t(12;17) in an
extraorbital giant cell angiofibroma. Cancer Genet
Cytogenet. 2006 Mar;165(2):157-60.
- 7. Thomas R, Banerjee SS, Eyden BP, Shanks JH, Bisset DL,
Hunt R, et al. A study of four cases of extra-orbital giant
cell angiofibromawith documentation of some unusual
features. Histopathology. 2001 Oct;39(4):390-6.
- 8. .Fletcher CD. Giant cell fibroblastoma of soft tissue: a
clinicopathological and immunohistochemical study.
Histopathology 1988;13:499-508.
- 9. Dalton WT, Zolliker AS, McCaughey WTE, Jacques J,
Kanerstein M. Localized primary tumors of the pleura.
Cancer 1979;44:1465-75.
- 10. Goodlad JR, Fletcher CD. Solitary fibrous tumour arising
at unusual sites: analysis of a series. Histopathology
1991;19:515- 22.