ADENOID KISTIK KARSINOM: BİR OLGU SUNUMU
Year 2024,
Volume: 3 Issue: 2, 80 - 83, 19.05.2024
Doğan Ilgaz Kaya
,
Ziya Ozan Cengiz
,
Gökhan Varlı
,
Beyza Öztaş
Abstract
Giriş:
Adenoid kistik karsinom (AKK), tükürük bezlerinden köken alan, nadir görülen bir kanser olup, indolent bir büyüme paterni sergilemekle birlikte agresif progresyon gösterir. ACC ile ilişkili yüksek metastatik potansiyel ve nüks oranı nedeniyle erken tanı çok önemlidir. Bu olgu sunumu, ACC'nin anlaşılmasına ve zamanında tanımlanmasına ve hasta yönetimi üzerindeki etkisine katkıda bulunmayı amaçlamaktadır.
Vaka:
Kırk iki yaşında erkek hasta sağ üst molar bölgede diş etinde kanama ve şişlik şikâyetiyle başvurdu. Radyolojik incelemede kemik rezorpsiyonuna neden olan radyolusent bir lezyon tespit edildi. Eksizyonel biyopsi ile ACC tanısı doğrulandı.
Tartışma:
AKK, çeşitli klinik özellikleri ve histolojik tipleri nedeniyle tanısal zorluklara yol açmakta ve sıklıkla gecikmiş teşhise neden olmaktadır. Etkili yönetim için hızlı tanı esastır. Bu olgu sunumu, erken teşhisin önemini vurgulamakta ve ACC'nin klinik ve patolojik yönlerini vurgulayarak tanınmasına ve uygun tedavisine yardımcı olmaktadır.
Ethical Statement
Yoktur.
Supporting Institution
Yoktur.
References
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parotid metastazing to liver: case report. BMC Cancer. 2004;4:41-
5.
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Thomas, C.Y. (2016), Adenoid cystic carcinoma: A review of recent
advances, molecular targets, and clinical trials. Head Neck, 38:
620-627.
- 3. Godge P, Sharma S, Yadav M. Adenoid cystic carcinoma of the
parotid gland. Contemp Clin Dent. 2012;3:223‐6
- 4. Kazancıoğlu HO, Çakır O, Ak G. Palatal Adenoid Kistik Karsinom.
Turkiye Klinikleri J Dental Sci. 2015;21:65-70.
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parotid gland. Contemp Clin Dent. 2012;3:223‐6
- 6. İnceoğlu B, Yakar EN, Şentürk MF, et al. Mandibulada Adenoid
Kistik Karsinoma: Olgu Sunumu. SDÜ Sağlık Bilimleri Enstitüsü
Dergisi. 2015;6:84-6.
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the dem-ographics, clinical features, and survival of patients
with adenoid cysticcarcinoma of major and minor salivary glands
versus less common siteswithin the Surveillance, Epidemiology,
and End Results registry.Cancer2012;118:3945–3953.
- 8. Chen AM, Bucci MK, Weinberg V, et al. Adenoid cystic carcinoma of
thehead and neck treated by surgery with or without postoperative
radiationtherapy: prognostic features of recurrence.Int J Radiat
Oncol Biol Phys2006;66:152–159.
- 9. Lupinetti AD, Roberts DB, Williams MD, Kupferman ME,
Rosenthal DI, Demonte F, El-Naggar A, Weber RS, Hanna EY.
Sinonasal adenoid cystic carcinoma: the M. D. Anderson Cancer
Center experience. Cancer. 2007;110(12):2726–2731. doi: 10.1002/
cncr.23096.
- 10. Garden AS, Weber RS, Morrison WH, Ang KK, Peters LJ. The
influenceof positive margins and nerve invasion in adenoid
cystic carcinoma of thehead and neck treated with surgery and
radiation.Int J Radiat Oncol BiolPhys1995;32:619–626
Adenoid Cystic Carcinoma: A Case Report
Year 2024,
Volume: 3 Issue: 2, 80 - 83, 19.05.2024
Doğan Ilgaz Kaya
,
Ziya Ozan Cengiz
,
Gökhan Varlı
,
Beyza Öztaş
Abstract
Introduction:
Adenoid cystic carcinoma (ACC) is a rare cancer originating from salivary glands, displaying an indolent growth pattern but aggressive progression. Early diagnosis is crucial due to the high metastatic potential and recurrence rate associated with ACC. This case report aims to contribute to the understanding and timely identification of ACC and its impact on patient management.
Case:
A 42-year-old male patient presented with bleeding and swelling of the gingiva in the right upper molar region. Radiological examination revealed a radiolucent lesion causing bone resorption. Excisional biopsy confirmed the diagnosis of ACC.
Discussion:
ACC poses diagnostic challenges due to its diverse clinical features and histological types, often leading to delayed detection. Prompt diagnosis is essential for effective management. This case report emphasizes the importance of early detection and highlights the clinical and pathological aspects of ACC, aiding in its recognition and appropriate treatment.
Supporting Institution
None
References
- 1. Harish K, Mangala Gouri SR. Adenoid cystic carcinoma of the
parotid metastazing to liver: case report. BMC Cancer. 2004;4:41-
5.
- 2. Dillon, P.M., Chakraborty, S., Moskaluk, C.A., Joshi, P.J. and
Thomas, C.Y. (2016), Adenoid cystic carcinoma: A review of recent
advances, molecular targets, and clinical trials. Head Neck, 38:
620-627.
- 3. Godge P, Sharma S, Yadav M. Adenoid cystic carcinoma of the
parotid gland. Contemp Clin Dent. 2012;3:223‐6
- 4. Kazancıoğlu HO, Çakır O, Ak G. Palatal Adenoid Kistik Karsinom.
Turkiye Klinikleri J Dental Sci. 2015;21:65-70.
- 5. Godge P, Sharma S, Yadav M. Adenoid cystic carcinoma of the
parotid gland. Contemp Clin Dent. 2012;3:223‐6
- 6. İnceoğlu B, Yakar EN, Şentürk MF, et al. Mandibulada Adenoid
Kistik Karsinoma: Olgu Sunumu. SDÜ Sağlık Bilimleri Enstitüsü
Dergisi. 2015;6:84-6.
- 7. Li N, Xu L, Zhao H, El-Naggar AK, Sturgis EM. A comparison of
the dem-ographics, clinical features, and survival of patients
with adenoid cysticcarcinoma of major and minor salivary glands
versus less common siteswithin the Surveillance, Epidemiology,
and End Results registry.Cancer2012;118:3945–3953.
- 8. Chen AM, Bucci MK, Weinberg V, et al. Adenoid cystic carcinoma of
thehead and neck treated by surgery with or without postoperative
radiationtherapy: prognostic features of recurrence.Int J Radiat
Oncol Biol Phys2006;66:152–159.
- 9. Lupinetti AD, Roberts DB, Williams MD, Kupferman ME,
Rosenthal DI, Demonte F, El-Naggar A, Weber RS, Hanna EY.
Sinonasal adenoid cystic carcinoma: the M. D. Anderson Cancer
Center experience. Cancer. 2007;110(12):2726–2731. doi: 10.1002/
cncr.23096.
- 10. Garden AS, Weber RS, Morrison WH, Ang KK, Peters LJ. The
influenceof positive margins and nerve invasion in adenoid
cystic carcinoma of thehead and neck treated with surgery and
radiation.Int J Radiat Oncol BiolPhys1995;32:619–626