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TÜRK DİŞ HEKİMLERİNİN BİFOSFONATA BAĞLI ÇENELERİN OSTEONEKROZU HAKKINDA BİLGİ VE FARKINDALIK DÜZEYİ: ANKET ÇALIŞMASI

Year 2024, Volume: 3 Issue: 3, 84 - 88, 27.09.2024

Abstract

Amaç: Bu çalışmanın amacı, Türkiye'deki genel diş hekimleri (GD) ve uzman diş hekimlerinin (SD) bisfosfonat ile ilişkili çene osteonekrozu (BRONJ) hakkındaki bilgi ve farkındalık düzeylerini değerlendirmektir. BRONJ, ilk olarak 2003 yılında tanımlanmış olup, osteoporoz ve metastatik malignitelerde kemik rezorpsiyonunu önlemek için kullanılan bisfosfonatlar (BP'ler) nedeniyle ortaya çıkmaktadır.
Gereç ve Yöntemler: Aralık 2014 - Haziran 2015 tarihleri arasında Türk Diş Hekimleri Birliği üyeleri arasında web tabanlı bir anket yapılmıştır. Anket iki bölümden oluşmuştur: demografik bilgiler ve BRONJ hakkında bilgi ve farkındalıkla ilgili sorular, klinik önemi, evreleri, tedavi deneyimi ve BP'lerin kullanılabileceği hastalıklar gibi konuları içermektedir.
Bulgular: Toplam 945 yanıt alınmış ve bu yanıtların 897'si (%94,9) eksiksiz olup çalışmaya dahil edilmiştir. Katılımcıların %72,2'si GD, %27,8'i ise SD idi. SD'lerin sadece %38,1'i ve GD'lerin %30'u BRONJ hakkında iyi bilgiye sahip olduklarını bildirmiştir. SD'lerin önemli bir kısmı (%74,6), GD'lere kıyasla (%59,8) tıbbi öykü alırken BP kullanımını sormaktadır (p<0,001). Ayrıca, GD'lerin %86'sı kendi başlarına hiç BRONJ vakası teşhis etmemiştir, bu da klinik deneyim ve bilgi eksikliğine işaret etmektedir. Çalışma, son mezunların, diş hekimliği müfredatındaki değişiklikler nedeniyle daha iyi farkındalığa sahip olduğunu ortaya koymuştur.
Sonuç: Türkiye'deki diş hekimleri genel olarak BRONJ konusunda farkındalığa sahip olsa da, özellikle GD'ler arasında bilgi ve tanı becerilerinin geliştirilmesi gerekmektedir. Türkiye'deki diş hekimlerinin BRONJ'u daha iyi anlamaları ve yönetmeleri için mezuniyet sonrası kurslar ve seminerler gibi eğitimlerin artırılması önerilmektedir.

References

  • 1. Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic. J Oral Maxillofac Surg. 2003;61(9):1115.
  • 2. López-Jornet P, Camacho-Alonso F, Molina-Miñano F, Gomez- Garcia F. Bisphosphonate-associated osteonecrosis of the jaw. Knowledge and attitudes of dentists and dental students: A preliminary study. J Eval Clin Pract. 2010 Oct;16(5):878-82.
  • 3. Reid IR. Osteonecrosis of the jaw: who gets it, and why? Bone. 2009 Jan;44(1):4-10.
  • 4. Alhussain A, Peel S, Dempster L, Clokie C, Azarpazhooh A. Knowledge, practices, and opinions of Ontario dentists when treating patients receiving bisphosphonates. J Oral Maxillofac Surg. 2015 Jun;73(6):1095-105.
  • 5. Ruggiero SL, Dodson TB, Assael LA, Landesberg R, Marx RE, Mehrotra B. American Association of Oral and Maxillofacial Surgeons Position Paper on Bisphosphonate-Related Osteonecrosis of the Jaw – 2009 Update. Aust Endod J. 2009 Dec;35(3):119-130.
  • 6. Sivolella S, Lumachi F, Stellini E, Favero L, Stellini E, Veltroni A, et al. Denosumab and antiangiogenetic drug-related osteonecrosis of the jaw: An uncommon but potentially severe disease. Anticancer Res. 2013 May;33(5):1793-7.
  • 7. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update. J Oral Maxillofac Surg. 2014 Oct;72(10):1938-1956.
  • 8. Vinitzky-Brener I, Ibáñez-Mancera NG, Aguilar-Rojas AM, Álvarez-Jardón AP. Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists. Med Oral Patol Oral Cir Bucal. 2017;22(1).
  • 9. Alhussain A, Peel S, Dempster L, Clokie C, Azarpazhooh A. Knowledge, practices, and opinions of Ontario dentists when treating patients receiving bisphosphonates. J Oral Maxillofac Surg. 2015;73:1095-1105.
  • 10. Yoo JY, Park YD, Kwon YD, Kim DY, Ohe JY. Survey of Korean dentists on the awareness on bisphosphonate-related osteonecrosis of the jaws. J Investig Clin Dent. 2010;1(2):90-95.
  • 11. Dougall A, Fiske J. Access to special care dentistry, part 5. Safety. Br Dent J. 2008 Aug;205(4):177-90.
  • 12. El Osta L, El Osta B, Lakiss S, Hennequin M, El Osta N. Bisphosphonate-related osteonecrosis of the jaw: awareness and level of knowledge of Lebanese physicians. Support Care Cancer. 2015 Nov;23(10):2825-31.
  • 13. Kazmi S, Siddiqui H, Khan F, Sarwar H, Latif M, Raza S, et al. Knowledge, attitudes and practices of physicians and dentists on medication-related osteonecrosis of the jaw: a cross-sectional survey. Br Dent J. 2023;234(3):151-6.
  • 14. Vinitzky-Brener I, Ibáñez-Mancera NG, Aguilar-Rojas AM, Álvarez-Jardón AP. Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists. Med Oral Patol Oral Cir Bucal. 2017 Jan;22(1).
  • 15. Al-Mohaya MA, Al-Khashan HI, Mishriky AM, Al-Otaibi LM. Physicians’ awareness of bisphosphonates-related osteonecrosis of the jaw. Saudi Med J. 2011;32:830-835.
  • 16. Tanna N, Steel C, Stagnell S, Bailey E. Awareness of medicationrelated osteonecrosis of the jaws (MRONJ) amongst general dental practitioners. Br Dent J. 2017;222:121–5.
  • 17. Kim J, Jeong S, Kim S, Kim Y. Perceptions of medical doctors on bisphosphonate-related osteonecrosis of the jaw. BMC Oral Health. 2016;16:77.

THE KNOWLEDGE AND AWARENESS LEVEL OF THE TURKISH DENTISTS ON BISPHOSPHONATE-RELATED OSTEONECROSİS OF THE JAWS: A SURVEY STUDY

Year 2024, Volume: 3 Issue: 3, 84 - 88, 27.09.2024

Abstract

Objective: This study aimed to evaluate the knowledge and awareness levels of general dentists (GDs) and specialist dentists (SDs) in Turkey regarding bisphosphonate-related osteonecrosis of the jaws (BRONJ).
Materials and Methods: A web-based survey was conducted from December 2014 to June 2015 among members of the Turkish Dental Association. The survey consisted of two sections: demographic information and questions about knowledge and awareness of BRONJ, such as awareness of its clinical importance, stages, treatment experience, and disorders where BPs can be used.
Results: A total of 945 responses were received, of which 897 (94.9%) were complete and included in the study. Of the respondents, 72.2% were GDs, and 27.8% were SDs. Only 38.1% of SDs and 30% of GDs reported good knowledge of BRONJ. A significant number of SDs (74.6%) asked about BP usage during medical history taking compared to 59.8% of GDs (p<0.001). Furthermore, 86% of GDs had never diagnosed a BRONJ case themselves.
Conclusion: While Turkish dentists are generally aware of BRONJ, there is a need for improved knowledge and diagnostic skills, especially among GDs. Enhanced education and training, including post-graduation courses and seminars, are recommended to improve the understanding and management of BRONJ among dental professionals in Turkiye

References

  • 1. Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic. J Oral Maxillofac Surg. 2003;61(9):1115.
  • 2. López-Jornet P, Camacho-Alonso F, Molina-Miñano F, Gomez- Garcia F. Bisphosphonate-associated osteonecrosis of the jaw. Knowledge and attitudes of dentists and dental students: A preliminary study. J Eval Clin Pract. 2010 Oct;16(5):878-82.
  • 3. Reid IR. Osteonecrosis of the jaw: who gets it, and why? Bone. 2009 Jan;44(1):4-10.
  • 4. Alhussain A, Peel S, Dempster L, Clokie C, Azarpazhooh A. Knowledge, practices, and opinions of Ontario dentists when treating patients receiving bisphosphonates. J Oral Maxillofac Surg. 2015 Jun;73(6):1095-105.
  • 5. Ruggiero SL, Dodson TB, Assael LA, Landesberg R, Marx RE, Mehrotra B. American Association of Oral and Maxillofacial Surgeons Position Paper on Bisphosphonate-Related Osteonecrosis of the Jaw – 2009 Update. Aust Endod J. 2009 Dec;35(3):119-130.
  • 6. Sivolella S, Lumachi F, Stellini E, Favero L, Stellini E, Veltroni A, et al. Denosumab and antiangiogenetic drug-related osteonecrosis of the jaw: An uncommon but potentially severe disease. Anticancer Res. 2013 May;33(5):1793-7.
  • 7. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update. J Oral Maxillofac Surg. 2014 Oct;72(10):1938-1956.
  • 8. Vinitzky-Brener I, Ibáñez-Mancera NG, Aguilar-Rojas AM, Álvarez-Jardón AP. Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists. Med Oral Patol Oral Cir Bucal. 2017;22(1).
  • 9. Alhussain A, Peel S, Dempster L, Clokie C, Azarpazhooh A. Knowledge, practices, and opinions of Ontario dentists when treating patients receiving bisphosphonates. J Oral Maxillofac Surg. 2015;73:1095-1105.
  • 10. Yoo JY, Park YD, Kwon YD, Kim DY, Ohe JY. Survey of Korean dentists on the awareness on bisphosphonate-related osteonecrosis of the jaws. J Investig Clin Dent. 2010;1(2):90-95.
  • 11. Dougall A, Fiske J. Access to special care dentistry, part 5. Safety. Br Dent J. 2008 Aug;205(4):177-90.
  • 12. El Osta L, El Osta B, Lakiss S, Hennequin M, El Osta N. Bisphosphonate-related osteonecrosis of the jaw: awareness and level of knowledge of Lebanese physicians. Support Care Cancer. 2015 Nov;23(10):2825-31.
  • 13. Kazmi S, Siddiqui H, Khan F, Sarwar H, Latif M, Raza S, et al. Knowledge, attitudes and practices of physicians and dentists on medication-related osteonecrosis of the jaw: a cross-sectional survey. Br Dent J. 2023;234(3):151-6.
  • 14. Vinitzky-Brener I, Ibáñez-Mancera NG, Aguilar-Rojas AM, Álvarez-Jardón AP. Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists. Med Oral Patol Oral Cir Bucal. 2017 Jan;22(1).
  • 15. Al-Mohaya MA, Al-Khashan HI, Mishriky AM, Al-Otaibi LM. Physicians’ awareness of bisphosphonates-related osteonecrosis of the jaw. Saudi Med J. 2011;32:830-835.
  • 16. Tanna N, Steel C, Stagnell S, Bailey E. Awareness of medicationrelated osteonecrosis of the jaws (MRONJ) amongst general dental practitioners. Br Dent J. 2017;222:121–5.
  • 17. Kim J, Jeong S, Kim S, Kim Y. Perceptions of medical doctors on bisphosphonate-related osteonecrosis of the jaw. BMC Oral Health. 2016;16:77.
There are 17 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section Research Articles
Authors

Emrah Soylu 0000-0002-9828-5096

Zeynep Burcin Gonen 0000-0003-2725-9330

Mert Şahin 0009-0007-6686-1136

Early Pub Date September 27, 2024
Publication Date September 27, 2024
Submission Date September 9, 2024
Acceptance Date September 11, 2024
Published in Issue Year 2024 Volume: 3 Issue: 3

Cite

Vancouver Soylu E, Gonen ZB, Şahin M. THE KNOWLEDGE AND AWARENESS LEVEL OF THE TURKISH DENTISTS ON BISPHOSPHONATE-RELATED OSTEONECROSİS OF THE JAWS: A SURVEY STUDY. EJOMS. 2024;3(3):84-8.

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