Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction

Alessandro D Aquino; Maria Noel Marzano-rodrigues; Natalia Bortotti Loureiro; Ivy Kiemle Trindade-suedam; Sergio Henrique Kiemle Trindade

Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction

Abstract

Objective: The aim of this article is to perform nasopharyngeal airway (NPA) morphometry of adults with cleft lip/ palate (CL/P); verify correlation with obstructive sleep apnea (OSA) severity; and compare !ndings with CL/P without OSA (N-OSA) and OSA without cleft (N-CL/P). Methods: Patients were divided into 3 groups: (G1) CL/P OSA; (G2) CL/P N-OSA; and (G3) N-CL/P OSA. Cone beam computed tomography images were used for three-dimensional reconstruction and morphometric analysis. Results: Volume NPA was larger in G1 than in G3. Length, width, inferior depth, areas, and inferior perimeter of NPA in G1 did not di"er from G2 or G3. The superior perimeter of G1 NPA di"ered signi!cantly from G3. Severity of OSA did not di"er between G1 and G3. Morphological variables and severity of OSA did not present a statistically signi!cant correlation. Conclusions: Cleft lip/palate obstructive sleep apnea patients presented larger nasopharyngeal areas than N-CL/P OSA. Findings suggest that OSA physiopathology in CLP patients has di"erent pathways than in OSA patients without a cleft.

Keywords

References

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Details

Primary Language

English

Subjects

Allergy

Journal Section

Research Article

Authors

Alessandro D Aquino This is me
Brazil

Maria Noel Marzano-rodrigues This is me
Brazil

Natalia Bortotti Loureiro This is me
Brazil

Ivy Kiemle Trindade-suedam This is me
Brazil

Sergio Henrique Kiemle Trindade This is me
Brazil

Publication Date

April 20, 2025

Submission Date

November 6, 2024

Acceptance Date

November 19, 2024

Published in Issue

Year 2025 Volume: 8 Number: 1

IZ

https://izlik.org/JA63LY23GA

Cite

RIS / Bibtex

APA

Aquino, A. D., Marzano-rodrigues, M. N., Loureiro, N. B., Trindade-suedam, I. K., & Trindade, S. H. K. (2025). Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction. European Journal of Rhinology and Allergy, 8(1), 12-18. https://izlik.org/JA63LY23GA

AMA

1.Aquino AD, Marzano-rodrigues MN, Loureiro NB, Trindade-suedam IK, Trindade SHK. Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction. Eur J Rhinol Allergy. 2025;8(1):12-18. https://izlik.org/JA63LY23GA

Chicago

Aquino, Alessandro D, Maria Noel Marzano-rodrigues, Natalia Bortotti Loureiro, Ivy Kiemle Trindade-suedam, and Sergio Henrique Kiemle Trindade. 2025. “Nasopharyngeal Morphometry in Adults With Cleft Lip Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction”. European Journal of Rhinology and Allergy 8 (1): 12-18. https://izlik.org/JA63LY23GA.

EndNote

Aquino AD, Marzano-rodrigues MN, Loureiro NB, Trindade-suedam IK, Trindade SHK (April 1, 2025) Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction. European Journal of Rhinology and Allergy 8 1 12–18.

IEEE

[1]A. D. Aquino, M. N. Marzano-rodrigues, N. B. Loureiro, I. K. Trindade-suedam, and S. H. K. Trindade, “Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction”, Eur J Rhinol Allergy, vol. 8, no. 1, pp. 12–18, Apr. 2025, [Online]. Available: https://izlik.org/JA63LY23GA

ISNAD

Aquino, Alessandro D - Marzano-rodrigues, Maria Noel - Loureiro, Natalia Bortotti - Trindade-suedam, Ivy Kiemle - Trindade, Sergio Henrique Kiemle. “Nasopharyngeal Morphometry in Adults With Cleft Lip Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction”. European Journal of Rhinology and Allergy 8/1 (April 1, 2025): 12-18. https://izlik.org/JA63LY23GA.

JAMA

1.Aquino AD, Marzano-rodrigues MN, Loureiro NB, Trindade-suedam IK, Trindade SHK. Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction. Eur J Rhinol Allergy. 2025;8:12–18.

MLA

Aquino, Alessandro D, et al. “Nasopharyngeal Morphometry in Adults With Cleft Lip Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction”. European Journal of Rhinology and Allergy, vol. 8, no. 1, Apr. 2025, pp. 12-18, https://izlik.org/JA63LY23GA.

Vancouver

1.Alessandro D Aquino, Maria Noel Marzano-rodrigues, Natalia Bortotti Loureiro, Ivy Kiemle Trindade-suedam, Sergio Henrique Kiemle Trindade. Nasopharyngeal Morphometry in Adults with Cleft Lip/Palate and Obstructive Sleep Apnea: Analysis by Computed Tomography and Three- Dimensional Reconstruction. Eur J Rhinol Allergy [Internet]. 2025 Apr. 1;8(1):12-8. Available from: https://izlik.org/JA63LY23GA