Evaluation of the Relationship Between SNOT-22 Test Results and Topographic Course of the Infraorbital Nerve in Patients with Chronic Rhinosinusitis

Year 2025, Volume: 8 Issue: 1, 31 - 35, 20.04.2025

Yusuf Çağdaş Kumbul Vural Akın Hasan Yasan Erdoğan Okur Fatma Caner Hanım Kumbul

Abstract

Objective: We aimed to evaluate whether course variations of the infraorbital nerve (ION) in chronic rhinosinusitis
(CRS) patients cause di"erences in the quality of life of patients using the Sino-Nasal Outcome Test-22 (SNOT-22).
Methods: Patients who applied to the otolaryngology clinic and were diagnosed with CRS were included in the study. Infraorbital nerve variations were de#ned as follows: type 1; the nerve is completely located within the sinus roof, type 2; the nerve canal is located under the roof but adjacent to it, and type 3; the nerve descending into the sinus lumen is suspended from a septation from the sinus roof or the lamella of the infraorbital ethmoid cell. Then, the relationship between the total scores of the patients who completed the SNOT-22 test and the ION variations was compared statistically.
Results: A total of 103 CRS patients were included in the study. Of these patients, 52 (50.5%) had ION type 1 course, 33 (32.0%) had ION type 2 course and 18 (17.5%) had ION type 3 course. When patients with ION types 1, 2, and 3 course were compared statistically in terms of age, there was no signi#cant di"erence (P = .545). The mean SNOT-22 total scores of patients with ION types 1, 2, and 3 were 43.60 ± 22.70, 46.70 ± 21.77, and 44.33 ± 17.68, respectively. There was no statistically signi#cant di"erence between ION types 1, 2, and 3 and SNOT-22 total scores (P = .810).
Conclusion: No relationship was found between SNOT-22 total scores and ION course variations in CRS patients.

Keywords

Infraorbital nerve , maxillary nerve , quality of life , rhinosinusitis , trigeminal nerve

References

• Reference 1. Ference&EH, Smith&SS, Conley&D, Chandra&RK. Surgical anatomy and variations of the infraorbital nerve. Laryngoscope. 2015;125(6):1296-1300. [CrossRef]
• Reference 2. Hu&KS, Kwak&HH, Song&WC, et&al. Branching patterns of the infraorbital nerve and topography within the infraorbital space. J Craniofac Surg. 2006;17(6):1111- 1115. [CrossRef]
• Reference 3. Tomaszewska&IM, Zwinczewska&H, G(adysz&T, Walocha&JA. Anatomy and clinical signi#cance of the maxillary nerve: a literature review. Folia Morphol (Warsz). 2015;74(2):150-156. [CrossRef]
• 4. Whyte&A, Boeddinghaus&R. The maxillary sinus: physiology, development and imaging anatomy. Dentomaxillofac Radiol. 2019;48(8):20190205. [CrossRef]
• 5. Fokkens&WJ, Lund&VJ, Hopkins&C, et&al. European position paper on rhinosinusi- tis and nasal polyps 2020. Rhinology. 2020;58(suppl S29):1-464. [CrossRef]
• 6. Piccirillo&JF, Merritt&MG Jr, Richards&ML. Psychometric and clinimetric validity of the 20-Item sino-nasal Outcome Test (SNOT-20). Otolaryngol Head Neck Surg. 2002;126(1):41-47. [CrossRef]
• 7. Hopkins&C, Gillett&S, Slack&R, Lund&VJ, Browne&JP. Psychometric validity of the 22-item sinonasal Outcome Test. Clin Otolaryngol. 2009;34(5):447-454. [CrossRef]
• 8. Cakir Cetin&A, Kumus&O, Keskinoglu&P, Sutay&S, Ecevit&MC. Turkish validation of the sino-nasal Outcome Test-22. Clin Otolaryngol. 2019;44(4):557-564. [CrossRef].
• 9. Dizdar&D, Bozan&A, Dizdar&SK, Göde&S, Alpay&HC. Evaluation of nasal symptoms in septoplasty patients using SNOT-22. Acta Otorhinolaryngol Ital. 2019;39(2):98- 102. [CrossRef]
• 10. Srouji& IA, Andrews& P, Edwards& C, Lund& VJ. General and rhinosinusitis-related quality of life in patients with Wegener's granulomatosis. Laryngoscope. 2006;116(9):1621-1625. [CrossRef]
• 11. de Vilhena&D, Duarte&D, Lopes&G. Sino-nasal Outcome Test-22: translation, cul- tural adaptation and validation in Portugal. Clin Otolaryngol. 2016;41(1):21-24. [CrossRef]
• 12. Akın& V, Kumbul& YÇ, Yasan& H, Ayyıldız& VA, Okur& E. Bilateral barotraumatic involvement of the infraorbital nerve with dehiscence and ectopic course: A case report. Turk Arch Otorhinolaryngol. 2023;61(3):134-137. [CrossRef]
• 13. Kim&JK, Yang&SK, Shin&DB, Nam&JG. Dehiscence of the infraorbital canal with the maxillary antral empyema: a new cause of facial pain. J Craniofac Surg. 2015;26(3):e227-e229. [CrossRef]
• 14. Yanagisawa&E, Yanagisawa&K. Endoscopic view of the infraorbital nerve. Ear Nose Throat J. 1999;78(4):226-228. [CrossRef]
• 15. Elnil&H, Al-Tubaikh&JA, El Beltagi&AH. Into the septum I go, a case of bilateral ectopic infraorbital nerves: a not-to-miss preoperative sinonasal CT variant. Neuroradiol J. 2014;27(2):146-149. [CrossRef]
• 16. Cappello&ZJ, Minutello&K, Dublin&AB. Anatomy, head and neck, nose paranasal sinuses. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.