Primary follicular lymphoma (PFL) is an uncommon subset of non-Hodgkin lymphoma known for its indolent nature, predominantly affecting lymph nodes. This report presents a rare case of PFL manifesting in the parotid gland, posing challenges in diagnosis and management. A 74-year-old female with pre-auricular swelling underwent diagnostic procedures, including contrast-enhanced computed tomography and fine needle aspiration cytology (FNAC), leading to an initial suspicion of pleomorphic adenoma. Subsequent core needle biopsy confirmed the diagnosis of
PFL, highlighting the need for comprehensive diagnostic approaches in unusual presentations. Notably, the patient’s favorable response to chemotherapy aligns with the typical indolent behavior of follicular lymphomas, emphasizing the importance of accurate diagnosis for tailored therapeutic interventions. This case underscores the significance of considering lymphoid malignancies in the differential diagnosis of parotid gland masses and contributes valuable insights into the diagnostic and management complexities of PFL in extranodal sites. Clinicians should remain vigilant
to such atypical presentations, recognizing the importance of a multimodal diagnostic approach and personalized treatment strategies.
| Primary Language | English |
|---|---|
| Subjects | Otorhinolaryngology |
| Journal Section | Case Report |
| Authors | |
| Submission Date | February 20, 2024 |
| Acceptance Date | April 2, 2024 |
| Publication Date | May 13, 2024 |
| Published in Issue | Year 2024 Volume: 7 Issue: 1 |
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