Research Article

Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019

Volume: 6 Number: 3 December 20, 2023
European Journal of Rhinology and Allergy Cover
European Journal of Rhinology and Allergy
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Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019

Abstract

Objective: While researchers have posited various factors, the precise etiology of anosmia in coronavirus disease 2019 (COVID-19) patients remains elusive. We aimed to investigate the relationship between the status of the nasal olfactory mucosal area and medical and demographic variables in patients with COVID-19-related olfactory dysfunction. Methods: In a retrospective analysis, we scrutinized data from 65 adult COVID-19 patients who exhibited olfactory impairment, excluding those with specific medical histories or age-related criteria. Our assessment comprised the analysis of paranasal sinus computed tomography scans to assess inflammation within the nasal olfactory mucosa. Olfactory testing was not employed in this study. We conducted a comprehensive investigation to explore potential associations with gender, age, septal deviation status, taste disorders, and the timing of the onset of olfactory dysfunction. Results: The average age of the patients was 31.6 ± 12.4 years, with 18 (27.7%) male and 47 (72.3%) female patients. Of 65 patients, 43 (66.2%) reported olfactory dysfunction simultaneously with COVID-19, while 22 (33.8%) experienced it after testing positive. Taste abnormalities were present in 49 patients (75.4%). Thirty-seven patients (56.9%) had a nasal septum deviation. Inflammation in the olfactory mucosal region was found in 8 patients (12.3%). The study did not find any significant association between inflammation in the olfactory mucosa and factors like age, gender, taste disorders, or the type of olfactory dysfunction. Still, a significant correlation was found between inflammation in the olfactory mucosal region and nasal septal deviation (P=.009). Conclusion: In COVID-19 patients with olfactory dysfunction, nasal septal deviation was the most common accompanying factor with olfactory mucosal area inflammation, suggesting it may be a potential risk factor.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

Buket Özel Bingöl This is me
0000-0001-6986-7639
Türkiye

Publication Date

December 20, 2023

Submission Date

August 31, 2023

Acceptance Date

October 13, 2023

Published in Issue

Year 2023 Volume: 6 Number: 3

DOI

https://doi.org/10.5152/ejra.2023.23105

IZ

https://izlik.org/JA69FX52ED

Cite

RIS / Bibtex
APA
Aksoy, A., Çırakoğlu, M. F., Bingöl, F., & Özel Bingöl, B. (2023). Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019. European Journal of Rhinology and Allergy, 6(3), 72-75. https://doi.org/10.5152/ejra.2023.23105
AMA
1.Aksoy A, Çırakoğlu MF, Bingöl F, Özel Bingöl B. Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019. Eur J Rhinol Allergy. 2023;6(3):72-75. doi:10.5152/ejra.2023.23105
Chicago
Aksoy, Ahmet, Mehmet Furkan Çırakoğlu, Fatih Bingöl, and Buket Özel Bingöl. 2023. “Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated With Coronavirus Disease 2019”. European Journal of Rhinology and Allergy 6 (3): 72-75. https://doi.org/10.5152/ejra.2023.23105.
EndNote
Aksoy A, Çırakoğlu MF, Bingöl F, Özel Bingöl B (December 1, 2023) Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019. European Journal of Rhinology and Allergy 6 3 72–75.
IEEE
[1]A. Aksoy, M. F. Çırakoğlu, F. Bingöl, and B. Özel Bingöl, “Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019”, Eur J Rhinol Allergy, vol. 6, no. 3, pp. 72–75, Dec. 2023, doi: 10.5152/ejra.2023.23105.
ISNAD
Aksoy, Ahmet - Çırakoğlu, Mehmet Furkan - Bingöl, Fatih - Özel Bingöl, Buket. “Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated With Coronavirus Disease 2019”. European Journal of Rhinology and Allergy 6/3 (December 1, 2023): 72-75. https://doi.org/10.5152/ejra.2023.23105.
JAMA
1.Aksoy A, Çırakoğlu MF, Bingöl F, Özel Bingöl B. Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019. Eur J Rhinol Allergy. 2023;6:72–75.
MLA
Aksoy, Ahmet, et al. “Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated With Coronavirus Disease 2019”. European Journal of Rhinology and Allergy, vol. 6, no. 3, Dec. 2023, pp. 72-75, doi:10.5152/ejra.2023.23105.
Vancouver
1.Ahmet Aksoy, Mehmet Furkan Çırakoğlu, Fatih Bingöl, Buket Özel Bingöl. Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019. Eur J Rhinol Allergy. 2023 Dec. 1;6(3):72-5. doi:10.5152/ejra.2023.23105

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