Case Report

Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection

Volume: 2 Number: 1 May 29, 2019
  • Eline Marin
  • Anali Dadgostar
  • Victor Leung
  • Amin Javer
European Journal of Rhinology and Allergy Cover
European Journal of Rhinology and Allergy
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Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection

Abstract

Sinonasal infection by Mycobacterium haemophilum is rare and has previously been reported only once in the literature. We reported a case of involvement of the sinonasal cavity in disseminated Mycobacterium haemophilum infection and presented a discussion on this condition. A 37-year-old female with a history of immune complex-mediated glomerulonephritis was diagnosed with disseminated Mycobacterium haemophilum infection and was started on a treatment regimen with clarithromycin, ciprofloxacin, and rifabutin. During the course of the disease, she experienced new-onset nasal congestion, hyposmia, and nasal crusting. Endoscopic evaluation in our clinic showed a septal perforation and extensive crusting throughout the nasal cavity. To combat this, the patient was administered steroid-impregnated irrigation. Despite receiving this local treatment, her symptoms persisted and she subsequently underwent endoscopic sinus surgery. Postoperatively, her sinonasal symptoms improved immediately. Awareness of Mycobacterium haemophilum rhinosinusitis may prove valuable to practicing otolaryngologists. An elevated index of suspicion is necessary when acid-fast bacillus staining is positive but routine mycobacterial cultures remain negative. Although standardized treatment protocols for the treatment of sinonasal involvement are yet to be established, appropriate antibiotic treatment, surgical debridement, and aggressive postoperative management are prudent for the effective management of the disease.

Keywords

References

  1. Lindeboom JA, Bruijnesteijn van Coppenraet LE, van Soolingen D, Prins JM, Kuijper EJ. Clinical manifestations, diagnosis, and treatment of Mycobacterium haemophilum infections. Clin Microbiol Rev 2011; 24: 701-17.
  2. Ducharlet K, Murphy C, Tan SJ, Dwyer KM, Goodman D, Aboltins C, et al. Recurrent Mycobacterium haemophilum in a renal transplant recipient. Nephrology 2014; 19 Suppl 1: 14-7.
  3. Saubolle MA, Kiehn TE, White MH, Rudinsky MF, Armstrong D. Mycobacterium haemophilum: microbiology and expanding clinical and geographic spectra of disease in humans. Clin Microbiol Rev 1996; 9: 435-47.
  4. Shah MK, Sebti A, Kiehn TE, Massarella SA, Sepkowitz KA. Mycobacterium haemophilum in immunocompromised patients. Clin Infect Dis 2001; 33: 330-7.
  5. Nabi S, Marglani OA, Javer AR. Mycobacterium Avium-intracellulare Sinusitis. J Otolaryngol Head Neck Surg 2010; 39: E51-5.

Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Case Report

Authors

Anali Dadgostar This is me
0000-0002-2596-4768
Canada

Publication Date

May 29, 2019

Submission Date

February 7, 2019

Acceptance Date

May 28, 2019

Published in Issue

Year 2019 Volume: 2 Number: 1

DOI

https://doi.org/10.5152/ejra.2019.102

IZ

https://izlik.org/JA56XW63SF

Cite

RIS / Bibtex
APA
Marin, E., Dadgostar, A., Leung, V., & Javer, A. (2019). Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection. European Journal of Rhinology and Allergy, 2(1), 29-31. https://doi.org/10.5152/ejra.2019.102
AMA
1.Marin E, Dadgostar A, Leung V, Javer A. Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection. Eur J Rhinol Allergy. 2019;2(1):29-31. doi:10.5152/ejra.2019.102
Chicago
Marin, Eline, Anali Dadgostar, Victor Leung, and Amin Javer. 2019. “Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection”. European Journal of Rhinology and Allergy 2 (1): 29-31. https://doi.org/10.5152/ejra.2019.102.
EndNote
Marin E, Dadgostar A, Leung V, Javer A (May 1, 2019) Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection. European Journal of Rhinology and Allergy 2 1 29–31.
IEEE
[1]E. Marin, A. Dadgostar, V. Leung, and A. Javer, “Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection”, Eur J Rhinol Allergy, vol. 2, no. 1, pp. 29–31, May 2019, doi: 10.5152/ejra.2019.102.
ISNAD
Marin, Eline - Dadgostar, Anali - Leung, Victor - Javer, Amin. “Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection”. European Journal of Rhinology and Allergy 2/1 (May 1, 2019): 29-31. https://doi.org/10.5152/ejra.2019.102.
JAMA
1.Marin E, Dadgostar A, Leung V, Javer A. Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection. Eur J Rhinol Allergy. 2019;2:29–31.
MLA
Marin, Eline, et al. “Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection”. European Journal of Rhinology and Allergy, vol. 2, no. 1, May 2019, pp. 29-31, doi:10.5152/ejra.2019.102.
Vancouver
1.Eline Marin, Anali Dadgostar, Victor Leung, Amin Javer. Sinonasal Involvement in Disseminated Mycobacterium Haemophilum Infection. Eur J Rhinol Allergy. 2019 May 1;2(1):29-31. doi:10.5152/ejra.2019.102

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