Case Report

Wegener Granulomatosis: Operated Nasal Septal Perforation

Volume: 1 Number: 3 March 6, 2019
European Journal of Rhinology and Allergy Cover
European Journal of Rhinology and Allergy
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Wegener Granulomatosis: Operated Nasal Septal Perforation

Abstract

Wegener’s granulomatosis is an idiopathic necrotizing granulatous vasculitis that can hold small and medium arteries, upper respiratory tract, lung and kidney involvement. It’s an ANCA associated vasculitis. c-ANCA positivity is considered very sensitive. In our case, a 40-year-old female patient was admitted to our hospital with complaints of nasal bleeding and crusting. The patient was operated due to idiopathic nasal septal perforation, was seen saddle nose deformity and 3x4 cm in size perforation in anterior septum and 1x2 cm in size perforation in posterior septum. Nasal biopsies of the patient with C-ANCA positivity were taken and the result of pathology came in harmony with Wegener’s granulomatosis. The patient was directed to the related clinic for the treatment of Wegener’s granulomatosis. Wegener Granulomatosis, which enters the diagnosis of idiopathic nasal septal perforation, is a disease that should be kept in mind.

Keywords

References

  1. Reinhold-Keller E, Beuge N, Latza U, de Groot K, Rudert H, Nolle B, et al. An interdisciplinary approach to the care of patients with Wegener’s granulomatosis: long-term outcome in 155 patients. Arthritis Rheum 2000; 43: 1021-32.
  2. Perincek G, Tabakoğlu E, Pamuk Ö.N. Massive Alveolar Hemorrhage During Wegener Granulomatosis: a Case Report. Balkan Med J 2011; 28: 463-65.
  3. Seo P, Stone JH. The antineutrophil cytoplasmic antibody-associated vasculitides. Am J Med 2004; 117: 39-50.
  4. Srouji IA, Andrews P, Edwards C, Lund VJ. Patterns of presentation and diagnosis of patients with Wegener’s granulomatosis: ENT aspects. J Laryngol Otol 2007; 121: 653-8.
  5. Janisiewicz AM, Klau MH, Keschner DB, Lehmer RR, Venkat KV, Medhekar SS, et al. Higher antineutrophil cytoplasmic antibody (C-ANCA) titers are associated with increased overall healthcare use in patients with sinonasal manifestations of granulomatosis with polyangiitis(GPA). Am J Rhinol Allergy. 2015; 29: 202-6.
  6. Gubbels SP, Barkhuizen A, Hwang PH. Head and neck manifestations of Wegener’s granulomatosis. Otolaryngol Clin North Am 2003; 36: 685-705.
  7. Rasmussen N. Management of the ear, nose, and throat manifestations of Wegener granulomatosis: an otorhinolaryngologist’s perspective. Curr Opin Rheumatol 2001; 13: 3-11.
  8. Van der Woude FJ, Rasmussen N, Lobatto S. Autoantibodies against neutrophils and monocytes: Tool for diagnosis and marker of disease activity in Wegener’s granulomatosis. Lancet 1985; 1: 425-42.

Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Case Report

Authors

Publication Date

March 6, 2019

Submission Date

November 5, 2017

Acceptance Date

January 12, 2018

Published in Issue

Year 2018 Volume: 1 Number: 3

DOI

https://doi.org/10.5152/ejra.2019.58092

IZ

https://izlik.org/JA94CN38WT

Cite

RIS / Bibtex
APA
Taş, B. M., Şimşek, G., Balcı, M., Güzelküçük Akay, H., & Kılıç, R. (2019). Wegener Granulomatosis: Operated Nasal Septal Perforation. European Journal of Rhinology and Allergy, 1(3), 84-86. https://doi.org/10.5152/ejra.2019.58092
AMA
1.Taş BM, Şimşek G, Balcı M, Güzelküçük Akay H, Kılıç R. Wegener Granulomatosis: Operated Nasal Septal Perforation. Eur J Rhinol Allergy. 2019;1(3):84-86. doi:10.5152/ejra.2019.58092
Chicago
Taş, Burak Mustafa, Gökçe Şimşek, Mahi Balcı, Hatice Güzelküçük Akay, and Rahmi Kılıç. 2019. “Wegener Granulomatosis: Operated Nasal Septal Perforation”. European Journal of Rhinology and Allergy 1 (3): 84-86. https://doi.org/10.5152/ejra.2019.58092.
EndNote
Taş BM, Şimşek G, Balcı M, Güzelküçük Akay H, Kılıç R (March 1, 2019) Wegener Granulomatosis: Operated Nasal Septal Perforation. European Journal of Rhinology and Allergy 1 3 84–86.
IEEE
[1]B. M. Taş, G. Şimşek, M. Balcı, H. Güzelküçük Akay, and R. Kılıç, “Wegener Granulomatosis: Operated Nasal Septal Perforation”, Eur J Rhinol Allergy, vol. 1, no. 3, pp. 84–86, Mar. 2019, doi: 10.5152/ejra.2019.58092.
ISNAD
Taş, Burak Mustafa - Şimşek, Gökçe - Balcı, Mahi - Güzelküçük Akay, Hatice - Kılıç, Rahmi. “Wegener Granulomatosis: Operated Nasal Septal Perforation”. European Journal of Rhinology and Allergy 1/3 (March 1, 2019): 84-86. https://doi.org/10.5152/ejra.2019.58092.
JAMA
1.Taş BM, Şimşek G, Balcı M, Güzelküçük Akay H, Kılıç R. Wegener Granulomatosis: Operated Nasal Septal Perforation. Eur J Rhinol Allergy. 2019;1:84–86.
MLA
Taş, Burak Mustafa, et al. “Wegener Granulomatosis: Operated Nasal Septal Perforation”. European Journal of Rhinology and Allergy, vol. 1, no. 3, Mar. 2019, pp. 84-86, doi:10.5152/ejra.2019.58092.
Vancouver
1.Burak Mustafa Taş, Gökçe Şimşek, Mahi Balcı, Hatice Güzelküçük Akay, Rahmi Kılıç. Wegener Granulomatosis: Operated Nasal Septal Perforation. Eur J Rhinol Allergy. 2019 Mar. 1;1(3):84-6. doi:10.5152/ejra.2019.58092

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