Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery

S Sathiyabama; Ahmed Mustafa

doi:10.65396/ejra.1825464

Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery

Abstract

OBJECTIVE The purpose of this study was to compare pre- and post-operative peak nasal inspiratory flow (PNIF) measurements to evaluate the benefits of septoplasty. Methods: A prospective study was conducted at the Department of Otorhinolaryngology in a tertiary healthcare center in Coimbatore from January 2019 to December 2021. Outpatient cases presenting with complaints of nasal blackness, along with severe and extreme nasal obstruction and septoplasty effectiveness (NOSE) scores, were included. PNIF was measured at baseline and after one month to analyze and compare the effectiveness of septoplasty. RESULTS The present study included data from 60 participants, of whom 23.3% were females and 76.7% were males. The preoperative PNIF was 51.17±6.40 L/min, while the postoperative PNIF was 119.33±14.13 L/min, with this difference being significant (p<0.001) and a positive correlation observed (r=0.440). Age had a significant negative correlation with both pre-op PNIF (r=-0.615, p<0.001) and post-op PNIF (r=-0.388, p=0.002). The difference in post-op PNIF was significant (p<0.001), with males showing greater improvement (mean post-op PNIF of 125.43 L/min) compared to females (99.29 L/min). CONCLUSION The results of this study suggest that septoplasty is an effective procedure for improving the mean PNIF among patients with nasal obstructions.

Keywords

References

1. Valero A, Navarro AM, Del Cuvillo A, et al. Position paper on nasal obstruction: evaluation and treatment. J Investig Allergol Clin Immunol. 2018;28(2):67-90.
2. Merma-Linares C, Martinez MD, Gonzalez M, Alobid I, Figuerola E, Mullol J. Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria. Curr Allergy Asthma Rep. 2023;23(10):567-578.
3. Schwartz JS, Tajudeen BA, Kennedy DW. Diseases of the nasal cavity. Handb Clin Neurol. 2019;164:285-302.
4. Mariño-Sanchez F, Valls-Mateus M, Haag O, Alobid I, Bousquet J, Mullol J. Smell loss is associated with severe and uncontrolled disease in children and adolescents with persistent allergic rhinitis. J Allergy Clin Immunol Pract. 2018;6(5):1752-1755.e3.
5. Alghamdi FS, Albogami D, Alsurayhi AS, et al. Nasal Septal Deviation: A Comprehensive Narrative Review. Cureus. 2022;14(11):e31317.
6. van Egmond MMHT, Rovers MM, Tillema AHJ, van Neerbeek N. Septoplasty for nasal obstruction due to a deviated nasal septum in adults: a systematic review. Rhinology. 2018;56(3):195-208.
7. van Egmond MMHT, Grutters JPC, Hannink G, van Heerbeek N, Rovers MM. Septoplasty versus non-surgical management for nasal obstruction in adults with a deviated septum: economic evaluation alongside a randomized controlled trial. BMC Med. 2020;18(1):101.
8. Schalek P, Guha A, Ondrová T, Svoboda M. Total and Unilateral Peak Nasal Inspiratory Flow and Unilateral Visual Analogue Scale: Rationale in Indication and Outcomes of Septoplasty? J Craniofac Surg. 2019;30(7):2004-2007.

9. Kumar RA, Deepthi P, Shreya D. Peak Nasal Inspiratory Flow: A Diagnostic Tool to Determine the Need for Septoplasty. Clin Rhinol An Int J. 2020;13(1):1–4.
10. Shastri K, Gao Y, Davis SJ, et al. Normative Values of the Nasal Obstruction Symptom Evaluation Scale. Facial Plast Surg Aesthet Med. 2023;25(1):35-39.
11. Srinivasan DG, Hegde J, Ramasamy K, et al. Comparison of the Efficacy of Septoplasty with Nonsurgical Management in Improving Nasal Obstruction in Patients with Deviated Nasal Septum - A Randomized Clinical Trial. Int Arch Otorhinolaryngol. 2021;26(2):e226-e232.
12. Bora A, Aslan Y, Durmuş K, Demirkıran BB, Altuntas EE. Do Mean Values of the Peak Inspiratory Nasal Flowmeter Vary According to the Severity, Direction and Type of Nasal Septum Deviation? Ind J Otolaryngol Head Neck Surg. 2022;74(Suppl 2):1675-1682.
13. Marzooq JA, Alasfoor F. Objective and Subjective Evaluation of Nasal Patency Post Septal Surgery: A Single Center Case Series. Acta Scientific Otolaryngology. 2021;3(7):2-6.
14. Carrie S, O’Hara J, Fouweather T, et al. Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial. BMJ. 2023;383:e075445.
15. Lodder WL, Leong SC. What are the clinically important outcome measures in the surgical management of nasal obstruction? Clin Otolaryngol. 2018;43:567–571.
16. Døsen LK, Kvinnesland K, TarAngen M, Shiryaeva O, Gay C, Haye R. Unilateral and Bilateral PNIF in Quality Control of Nasal Septal Surgery. Int J Otolaryngol. 2018;2018:7846843.
17. Fulkerson PC, Rothenberg ME. Targeting eosinophils in allergy, inflammation and beyond. Nat Rev Drug Discov. 2013;12(2):117-29.
18. Macchia I, La Sorsa V, Urbani F, et al. Eosinophils as potential biomarkers in respiratory viral infections. Front Immunol. 2023;14:1170035.

Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

S Sathiyabama This is me
India

Ahmed Mustafa This is me
India

Publication Date

August 31, 2025

Submission Date

December 12, 2024

Acceptance Date

March 3, 2025

Published in Issue

Year 2025 Volume: 8 Number: 2

DOI

https://doi.org/10.65396/ejra.1825464

IZ

https://izlik.org/JA34YC85CL

Cite

RIS / Bibtex

APA

Sathiyabama, S., & Mustafa, A. (2025). Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery. European Journal of Rhinology and Allergy, 8(2), 68-72. https://doi.org/10.65396/ejra.1825464

AMA

1.Sathiyabama S, Mustafa A. Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery. Eur J Rhinol Allergy. 2025;8(2):68-72. doi:10.65396/ejra.1825464

Chicago

Sathiyabama, S, and Ahmed Mustafa. 2025. “Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery”. European Journal of Rhinology and Allergy 8 (2): 68-72. https://doi.org/10.65396/ejra.1825464.

EndNote

Sathiyabama S, Mustafa A (August 1, 2025) Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery. European Journal of Rhinology and Allergy 8 2 68–72.

IEEE

[1]S. Sathiyabama and A. Mustafa, “Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery”, Eur J Rhinol Allergy, vol. 8, no. 2, pp. 68–72, Aug. 2025, doi: 10.65396/ejra.1825464.

ISNAD

Sathiyabama, S - Mustafa, Ahmed. “Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery”. European Journal of Rhinology and Allergy 8/2 (August 1, 2025): 68-72. https://doi.org/10.65396/ejra.1825464.

JAMA

1.Sathiyabama S, Mustafa A. Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery. Eur J Rhinol Allergy. 2025;8:68–72.

MLA

Sathiyabama, S, and Ahmed Mustafa. “Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery”. European Journal of Rhinology and Allergy, vol. 8, no. 2, Aug. 2025, pp. 68-72, doi:10.65396/ejra.1825464.

Vancouver

1.S Sathiyabama, Ahmed Mustafa. Clinical Significance of Peak Nasal Inspiratory Flow to Assess Outcome Before and After Septoplasty Surgery. Eur J Rhinol Allergy. 2025 Aug. 1;8(2):68-72. doi:10.65396/ejra.1825464