The Effect of Nasal Septal Deviation on Serum Lipid Levels
Year 2019,
Volume: 2 Issue: 1, 13 - 16, 29.05.2019
Duran Karataş
,
Adnan Ekinci
,
Abdurrahman Yetiş
,
Müge Özcan
Abstract
Objective: The aim of the study was to determine the effect of nasal septal deviation on serum lipids.
Material and Methods: Thirty-two patients aged 18-53 with nasal septal deviation and nasal obstruction were included into this study. Serum lipid levels were determined before and after septoplasty.
Results: There was no statistically significant difference in serum lipid levels before and after septoplasty (p=0.248, p=0.135, p=0.862, p=0.829). There was a statistically significant difference in the serum low-density lipoprotein cholesterol level between the patient and control group (p=0.024).
Conclusion: This study showed that nasal septal deviations had no effect on serum lipids, except on low-density lipoprotein cholesterol. Septoplasty can reduce the speed of atherosclerosis progression in patients with both atherosclerosis and nasal septal deviation.
References
-
Acar B, Yavuz B, Karabulut H, Gunbey E, Babademez MA, Yalçın AA, et al. Parasympathetic overactivity in patients with nasal septum deformities. Eur Arch Otorhinoleryngol 2010; 267: 73-6.
-
Derin S, Deveer M, Sahan M, Beydilli H. Giant concha bullosa. BMJ Case Rep 2014; DOI: 10.1136/bcr-2013-200524.
-
Yurttas V, Şereflican M, Erkoçoğlu M, Terzi EH, Kükner A, Oral M. Histopathological effects of intranasal phototheraphy and nasal corticosteroids in allergic rhinitis in a rabbit model. J Photocem Photobiol B 2015; 149: 289-91.
-
Stokes KY, Cooper D, Tailor A, Granger DN. Hypercholesterolemia promotes inflammation and microvascular dysfunction: role of nitric oxide and superoxide. Free Radic Biol Med 2002; 33: 1026-36.
-
Vinding RK, Stokholm J, Chawes BL, Bisgaard H. Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization. J Allergy Clin Immunol 2016; 137: 68-74.
-
Ahn JC, Lee WH, We J, Rhee CS, Lee C, Kim JW. Nasal septal deviation with obstructive symptoms: Association found with asthma but not with other general health problems. Am J Rhinol Allergy 2016; 30: 17-20.
-
Michailidis V, Steiropoulos P, Nena E, Papanas N, Maltezos E, Bouros D. Continuous positive airway pressure treatment: effect on serum lipids in patients with obstructive sleep apnoea. Open Cardiovasc Med J 2011; 5: 231-8.
-
Mladina R, Cujić E, Subarić M, Vuković K. Nasal septal deformities in ear, nose, and throat patients: an international study. Am J Otolaryngol 2008; 29: 75-82.
-
Gowdy KM, Fessler MB. Emerging roles for cholesterol and lipoproteins in lung disease. Pulm Pharmacol Ther 2013; 26: 430-7.
-
Derin S, Akın F, Şahan M, Altun İ, Şahin C, Eliçora SŞ. Impact of markedly nasal septal deviation on 24-hour rhythm Holter findings. Kulak Burun Bogaz Ihtis Derg 2015; 25: 284-8.
-
Fidan V, Aksakal E. Impact of septoplasty on pulmonary pressure in patients with markedly deviated septum. J Craniofac Surg 2011; 22: 1591-3.
-
Zong J, Liu Y, Huang Y, Chen J, Gao L, Zhang C, et al. Serum lipids alterations in adenoid hypertrophy or adenotonsillar hypertrophy children with sleep disordered breathing. Int J Pediatr Otorhinolaryngol 2013; 77: 717-20.
-
Li X, Tang H, Wang J, Xie X, Liu P, Kong Y, et al. The effect of preoperative serum triglycerides and high-density lipoprotein-cholesterol levels on the prognosis of breast cancer. Breast 2017; 32: 1-6.
-
Acharya S, Rai P, Hallikeri K, Anehosur V, Kale J. Serum lipid profile in oral squamous cell carcinoma: alterations and association with some clinicopathological parameters and tobacco use. Int J Oral Maxillofac Surg 2016; 45: 713-20.
-
Emerging Risk Factors Collaboration, Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK, et al. Major lipids, apolipoproteins, and risk of vascular disease. JAMA 2009; 302: 1993-2000.
-
Li L, Zhan X, Wang N, Pinto JM, Ge X, Wang C, et al. Does airway surgery lower serum lipid levels in obstructive sleep apnea patients? A retrospective case review. Med Sci Monit 2014; 20: 2651-7.
-
Nadeem R, Singh M, Nida M, Kwon S, Sajid H, Witkowski J, et al. Effect of CPAP treatment for obstructive sleep apnea hypopnea syndrome on lipid profile: a meta-regression analysis. J Clin Sleep Med 2014; 10: 1295-302.
-
Kahveci OK, Miman MC, Yucel A, Yucedag F, Okur E, Altuntas A The efficiency of Nose Obstruction Symptom Evaluation (NOSE) scale on patients with nasal septal deviation. Auris Nasus Larynx 2012; 39: 275-9.