“Paraquat Brain”: Have We Researched Enough?

Year 2023, , 25 - 28, 31.12.2023

Ananth Rupesh Kattamreddy , Mohit Kumar Moses Thathapudi Victor Ghosh Jacinth Karunya Midde , Pravin Kalyankar

https://doi.org/10.51262/ejtox.1344451

Abstract

This letter examines the potential relationship between the highly toxic herbicide paraquat (PQ) and Parkinson's disease (PD). Despite animal studies implicating PQ as a causative factor for PD, the evidence is insufficient due to limited human research on this topic. There is a pressing need for human autopsy-based studies in PQ poisoning fatalities to comprehend paraquat's neuropathology. Further studies are crucial to assess the morbidity in paraquat poisoning survivors, potentially shedding light on clinical links with PD. Although current research hasn't definitively established a causal connection, the absence of evidence shouldn't discourage ongoing investigation. The pursuit of understanding the PQ-PD connection necessitates unwavering commitment from the scientific community.

Keywords

Paraquat, parkinson's disease, toxicology, neurotoxicants

Supporting Institution

Not Applicable

Project Number

Not Applicable

Thanks

Nil

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